MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 751 to 800 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Interaction Map	red	green	network_comparison
arg/abl-interacting protein 2 isoform 2; arg binding protein 2. [refseq;acc:nm_021069]	947	SORBS2	High confidence	212.51	205.191	1.03567
arginase 1 (ec 3.5.3.1) (liver-type arginase). [swissprot;acc:p05089]	1389	ARG1	Low confidence	201.124	196.809	1.02192
	1885		High confidence	204.44	206.615	1.01064
arginase ii, mitochondrial precursor (ec 3.5.3.1) (non-hepatic arginase) (kidney-type arginase). [swissprot;acc:p78540]	1402	ARG2	Low confidence	201.12	196.811	1.02189
	1886		High confidence	204.512	206.682	1.01061
arginine-glutamic acid dipeptide (re) repeats; atrophin 1-like; arginine glutamic acid dipeptide re repeats. [refseq;acc:nm_012102]	1379	RERE		218.47	213.875	1.02148
	1432		Low confidence	203.206	198.891	1.0217
arginine/serine-rich splicing factor 10 (transformer-2-beta) (htra2- beta) (transformer 2 protein homolog) (silica-induced protein 41) (ra301). [swissprot;acc:q15815]	1361	SFRS10		203.394	199.014	1.02201
	1478		High confidence	215.122	211.066	1.01922
argininosuccinate lyase (ec 4.3.2.1) (arginosuccinase) (asal). [swissprot;acc:p04424]	1962	ASL	Low confidence	194.702	190.961	1.01959
	2108		High confidence	216.36	217.93	1.00726
argininosuccinate synthase (ec 6.3.4.5) (citrulline--aspartate ligase). [swissprot;acc:p00966]	1546	ASS1		217.769	221.474	1.01701
	1591		Low confidence	193.407	189.426	1.02102
arginyl-trna synthetase-like; arginine-trna ligase. [refseq;acc:nm_020320]	1958	RARS2		200.858	196.994	1.01961
	2235		High confidence	200.95	199.711	1.0062
ariadne-1 protein homolog (ari-1) (ubiquitin-conjugating enzyme e2- binding protein 1) (ubch7-binding protein) (ubcm4-interacting protein) (hhari) (h7-ap2) (hussy-27) (mop-6). [swissprot;acc:q9y4x5]	2707	ARIH1	Low confidence	186.752	183.532	1.01754
ariadne-2 protein homolog (ari-2) (triad1 protein) (ht005). [swissprot;acc:o95376]	2798	ARIH2	High confidence	0.00001	0.00001	1
	2895		Low confidence	199.625	196.273	1.01708
arl-6 interacting protein-1 (aip-1). [swissprot;acc:q15041]	1458	ARL6IP1		201.463	197.207	1.02158
armet protein precursor (arginine-rich protein). [swissprot;acc:p55145]	1521	ARMET		203.641	199.39	1.02132
	1714		High confidence	206.549	203.844	1.01327
arp2/3 complex 16 kda subunit (p16-arc) (actin-related protein 2/3 complex subunit 5). [swissprot;acc:o15511]	1211	ARPC5	Low confidence	201.559	197.042	1.02292
	2602		High confidence	224.875	225.192	1.00141
arp2/3 complex 21 kda subunit (p21-arc) (actin-related protein 2/3 complex subunit 3). [swissprot;acc:o15145]	575	ARPC3	Low confidence	202.85	196.777	1.03086
	2632		High confidence	224.891	225.195	1.00135
arp2/3 complex 34 kda subunit (p34-arc) (actin-related protein 2/3 complex subunit 2). [swissprot;acc:o15144]	615	ARPC2	Low confidence	203.495	197.661	1.02952
	2697		High confidence	225.081	225.232	1.00067
arp2/3 complex 41 kda subunit (p41-arc) (actin-related protein 2/3 complex subunit 1b). [swissprot;acc:o15143]	718	ARPC1B	Low confidence	201.612	196.213	1.02752
	2629		High confidence	224.891	225.195	1.00135
arsenical pump-driving atpase (ec 3.6.3.16) (arsenite-translocating atpase) (arsenical resistance atpase) (arsenite-transporting atpase) (arsa) (asna-i). [swissprot;acc:o43681]	2291	no value		200.158	201.213	1.00527
	4775		Low confidence	203.794	202.869	1.00456
aryl-hydrocarbon interacting protein-like 1. [swissprot;acc:q9nzn9]	1156	AIPL1	High confidence	224.307	230.242	1.02646
	3724		Low confidence	200.624	197.938	1.01357
asc-1 complex subunit p100. [refseq;acc:nm_032204]	797	ASCC2		211.636	206.184	1.02644
	1374		High confidence	216.542	211.908	1.02187
asc-type amino acid transporter 1 (asc-1). [swissprot;acc:q9ns82]	278	SLC7A10	Low confidence	205.006	196.369	1.04398
asf1 anti-silencing function 1 homolog a; anti-silencing function 1a; ccg1-interacting factor a. [refseq;acc:nm_014034]	1931	ASF1A		200.05	196.186	1.0197
asf1 anti-silencing function 1 homolog b; anti-silencing function 1b. [refseq;acc:nm_018154]	1921	ASF1B		200.04	196.171	1.01972
asp (abnormal spindle)-like, microcephaly associated; microcephaly, primary autosomal recessive 5. [refseq;acc:nm_018136]	2055	ASPM		199.194	195.415	1.01934
asparaginase-like 1 protein. [refseq;acc:nm_025080]	4569	ASRGL1		206.65	208.245	1.00772
asparagine synthetase [glutamine-hydrolyzing] (ec 6.3.5.4) (glutamine- dependent asparagine synthetase) (ts11 cell cycle control protein). [swissprot;acc:p08243]	1057	ASNS	High confidence	219.01	212.468	1.03079
	1140		Low confidence	187.8	183.496	1.02346
asparaginyl-trna synthetase, cytoplasmic (ec 6.1.1.22) (asparagine-- trna ligase) (asnrs). [swissprot;acc:o43776]	1624	NARS		201.291	197.189	1.0208
	2323		High confidence	192.773	193.691	1.00476
aspartate aminotransferase, cytoplasmic (ec 2.6.1.1) (transaminase a) (glutamate oxaloacetate transaminase-1). [swissprot;acc:p17174]	1042	GOT1	Low confidence	203.079	198.289	1.02416
aspartate aminotransferase, mitochondrial precursor (ec 2.6.1.1) (transaminase a) (glutamate oxaloacetate transaminase-2). [swissprot;acc:p00505]	1045	GOT2		203.088	198.3	1.02415
aspartate beta-hydroxylase isoform b; junctin isoform 1; junctate; aspartyl/asparaginyl-beta-hydroxylase; peptide-aspartate beta-dioxygenase; humbug. [refseq;acc:nm_032468]	658	no value	High confidence	229.072	216.576	1.0577
	819		Low confidence	208.488	203.181	1.02612
aspartyl aminopeptidase (ec 3.4.11.21). [swissprot;acc:q9ula0]	1979	DNPEP		194.278	190.557	1.01953
aspartyl protease 3 (fragment). [sptrembl;acc:q9uhb3]	1746	NAPSB		198.281	194.322	1.02037

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.