MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 730 to 779 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	green	network_comparison
axonemal dynein light intermediate polypeptide 1 (inner dynein arm light chain, axonemal) (hp28). [swissprot;acc:o14645]	2003	DNALI1	Divided	208.315	206.41	1.00923
b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [refseq;acc:nm_181844]	1559	BCL6B		196.191	192.996	1.01655
	1632		Subtracted			3.195
b-cell lymphoma 3-encoded protein (bcl-3 protein). [swissprot;acc:p20749]	2655	BCL3	Divided	201.445	201.667	1.0011
	2661		Subtracted			0.222
b-cell lymphoma 6 protein (bcl-6) (zinc finger protein 51) (laz-3 protein) (bcl-5). [swissprot;acc:p41182]	1556	BCL6	Divided	196.192	192.996	1.01656
	1630		Subtracted			3.196
b-raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (p94) (v-raf murine sarcoma viral oncogene homolog b1). [swissprot;acc:p15056]	980	BRAF	Divided	130.289	134.713	1.03396
	1393		Subtracted			4.424
b9 protein; likely ortholog of mouse endothelial precursor protein b9. [refseq;acc:nm_015681]	114	B9D1		229.818	267.265	37.447
	181		Divided			1.16294
ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5]	188	GSTO2	Subtracted	227.357	254.15	26.793
	244		Divided			1.11785
ba138e2.1.2 (formin-binding protein 17 (fbp17), isoform 2). [sptrembl;acc:q96lh6]	457	FNBP1	Subtracted	210.578	226.764	16.186
	464		Divided			1.07686
ba203i16.1 (hypothetical protein kiaa0970). [sptrembl;acc:q9h1w1]	3117	FNDC3A		0.00001	0.00001	1
			Subtracted	0	0	0
ba207c16.2 (fragment). [sptrembl;acc:q9nql7]	2599	KIAA1432	Divided	211.662	211.361	1.00142
	2625		Subtracted			0.301
ba271b5.1 (similar to ribosomal protein s7). [sptrembl;acc:q9h1s9]	2125	no value		217.871	219.366	1.495
	2148		Divided			1.00686
ba304i5.1 (novel lipase) (fragment). [sptrembl;acc:q96lg2]	2115	LIPM		214.632	213.14	1.007
	2130		Subtracted			1.492
ba305p22.3 (breast carcinoma amplified sequence 4). [sptrembl;acc:q8ndy6]	931	BHLHB4	Divided	159.13	164.917	1.03637
	1110		Subtracted			5.787
ba395l14.12 (novel protein similar to small nuclear ribonucleoprotein polypeptide a' (snrpa1)). [sptrembl;acc:q9nu36]	452	no value	Divided	224.161	207.972	1.07784
	455		Subtracted			16.189
ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	1551			221.128	224.767	3.639
	1568		Divided			1.01646
ba528a10.3.2 (novel protein similar to kiaa0161, isoform 2) (fragment). [sptrembl;acc:q9bx39]	2968	RNF144B		0.00001	0.00001	1
			Subtracted	0	0	0
bactericidal permeability-increasing protein precursor (bpi) (cap 57). [swissprot;acc:p17213]	717	BPI		224.434	235.583	11.149
	757		Divided			1.04968
baculoviral iap repeat-containing protein 5 (apoptosis inhibitor survivin) (apoptosis inhibitor 4). [swissprot;acc:o15392]	2487	BIRC5	Subtracted	218.949	219.552	0.603
	2500		Divided			1.00275
bag-family molecular chaperone regulator-1 (bcl-2 binding athanogene- 1) (bag-1) (glucocorticoid receptor-associated protein rap46). [swissprot;acc:q99933]	2185	BAG1		211.713	210.318	1.00663
	2189		Subtracted			1.395
bag-family molecular chaperone regulator-2. [swissprot;acc:o95816]	1785	BAG2	Divided	206.332	203.874	1.01206
	1809		Subtracted			2.458
bag-family molecular chaperone regulator-3 (bcl-2 binding athanogene- 3) (bag-3) (bcl-2-binding protein bis) (docking protein cair-1). [swissprot;acc:o95817]	431	BAG3		233.529	216.737	16.792
	459		Divided			1.07748
bai1-associated protein 1; ww domain-containing protein 3; atrophin-1 interacting protein 3. [refseq;acc:nm_004742]	955	MAGI1	Subtracted	221.73	228.906	7.176
	1015		Divided			1.03236
bai1-associated protein 3; bai-associated protein 3. [refseq;acc:nm_003933]	584	BAIAP3	Subtracted	233.725	220.751	12.974
	651		Divided			1.05877
band 4.1-like protein 1 (neuronal protein 4.1) (4.1n). [swissprot;acc:q9h4g0]	2144	EPB41L1		206.443	207.864	1.00688
	2163		Subtracted			1.421
band 4.1-like protein 2 (generally expressed protein 4.1) (4.1g). [swissprot;acc:o43491]	2146	EPB41L2	Divided			1.00688
	2164		Subtracted			1.421
band 4.1-like protein 3 (4.1b) (differentially expressed in adenocarcinoma of the lung protein 1) (dal-1). [swissprot;acc:q9y2j2]	2145	EPB41L3	Divided	206.442	207.862	1.00688

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.