MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Filtered	Interaction Map	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 1892 in total

Network Comparison Type  : Subtracted
Filtered  : 1
Interaction Map  : High confidence
network_comparison  : 0
red  : 0
green  : 0

Rank	description	Value Type
2756	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	Measured
		Ranked
		Squared
		Rooted
2757	nucleosome assembly protein 1-like 1 (nap-1 related protein). [swissprot;acc:p55209]	Measured
		Ranked
		Squared
		Rooted
2758	nucleosome assembly protein 1-like 2 (brain-specific protein, x- linked). [swissprot;acc:q9ulw6]	Measured
		Ranked
		Squared
		Rooted
2759	retinoic acid receptor rxr-alpha. [swissprot;acc:p19793]	Measured
		Ranked
		Squared
		Rooted
2760	t-cell acute lymphocytic leukemia-2 protein (tal-2 protein). [swissprot;acc:q16559]	Measured
		Ranked
		Squared
		Rooted
2761	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]	Measured
		Ranked
		Squared
		Rooted
2762	developmentally regulated gtp-binding protein 1 (drg 1). [swissprot;acc:q9y295]	Measured
		Ranked
		Squared
		Rooted
2763	ring finger protein 3. [refseq;acc:nm_006315]	Measured
		Ranked
		Squared
		Rooted
2764	ras-related protein rab-11b (gtp-binding protein ypt3). [swissprot;acc:q15907]	Measured
		Ranked
		Squared
		Rooted
2765	histone h2a.e (h2a/e). [swissprot;acc:q99878]	Measured
		Ranked
		Squared
		Rooted
2766	ss18-like protein 1 (syt homolog-1). [swissprot;acc:o75177]	Measured
		Ranked
		Squared
		Rooted
2767	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured
		Ranked
		Squared
		Rooted
2768	histone h2a.x (h2a/x). [swissprot;acc:p16104]	Measured
		Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.