MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Hugo	Value Type	Network Comparison Type	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 680 to 729 of 3228 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Hugo	red	green	network_comparison
680	homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483]	HOXB4	132.413	125.389	1.05602
681	homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444]	HOXC5
682	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	no value
683	homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016]	HOXD4
684	homeobox protein hox-b5 (hox-2a) (hho.c10) (hu-1). [swissprot;acc:p09067]	HOXB5
685	homeobox protein hox-a5 (hox-1c). [swissprot;acc:p20719]	HOXA5
686	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	no value
687	retinal short-chain dehydrogenase/reductase 3. [refseq;acc:nm_016246]	HSD17B14
688	dna-directed rna polymerase ii 16 kda polypeptide (ec 2.7.7.6) (rpb4). [swissprot;acc:o15514]	POLR2D	237.554	250.823	1.05586
689	t-complex protein 1, alpha subunit (tcp-1-alpha) (cct-alpha). [swissprot;acc:p17987]	TCP1	135.379	128.225	1.05579
690	nuclear protein skip (ski-interacting protein) (snw1 protein) (nuclear receptor coactivator ncoa-62). [swissprot;acc:q13573]	SNW1	220.593	208.987	1.05553
691	breast carcinoma amplified sequence 2; spliceosome associated protein, amplified in breast cancer. [refseq;acc:nm_005872]	BCAS2	217.602	206.195	1.05532
692	cdc5-like; cdc5 (cell division cycle 5, s. pombe, homolog)-like; cell division cycle 5, s. pombe, homolog-like; cdc5-related protein. [refseq;acc:nm_001253]	CDC5L
693	rna-binding protein nova-1 (neuro-oncological ventral antigen 1) (onconeural ventral antigen-1) (paraneoplastic ri antigen) (ventral neuron-specific protein 1). [swissprot;acc:p51513]	NOVA1	222.554	234.847	1.05524
694	dna polymerase epsilon, catalytic subunit a (ec 2.7.7.7) (dna polymerase ii subunit a). [swissprot;acc:q07864]	POLE	241.907	229.35	1.05475
695	peptidylprolyl isomerase-like 4; cyclophilin-type peptidyl-prolyl cis-trans isomerase; ppiase; serologically defined breast cancer antigen ny-br-18. [refseq;acc:nm_139126]	PPIL4	226.135	214.405	1.05471
696	sr rich protein. [refseq;acc:nm_032870]	SFRS18	225.293	213.64	1.05455
697	ferritin heavy chain (ferritin h subunit). [swissprot;acc:p02794]	FTH1	220.444	209.113	1.05419
698	mitochondrial ferritin; ferritin heavy chain-like; ferritin h subunit. [refseq;acc:nm_177478]	FTMT	220.437	209.118	1.05413
699	cellular repressor of e1a-stimulated genes 2. [refseq;acc:nm_153836]	CREG2	220.438
700	dj681n20.2 (novel protein similar to ferritin, light polypeptide (ftl)). [sptrembl;acc:q9byw6]	no value
701	disks large-associated protein 1 (dap-1) (guanylate kinase-associated protein) (hgkap) (sap90/psd-95-associated protein 1) (sapap1) (psd- 95/sap90 binding protein 1). [swissprot;acc:o14490]	DLGAP1
702	putative adenosylhomocysteinase 2 (ec 3.3.1.1) (s-adenosyl-l- homocysteine hydrolase) (adohcyase). [swissprot;acc:o43865]	AHCYL1
703	limkain b1. [refseq;acc:nm_019081]	KIAA0430
704	putative adenosylhomocysteinase 3 (ec 3.3.1.1) (s-adenosyl-l- homocysteine hydrolase) (adohcyase). [swissprot;acc:q96hn2]	no value
705	cellular repressor of e1a-stimulated genes. [refseq;acc:nm_003851]	CREG1
706	disks large-associated protein 3 (dap-3) (sap90/psd-95-associated protein 3) (sapap3) (psd-95/sap90 binding protein 3) (fragment). [swissprot;acc:o95886]	DLGAP3
707	kininogen precursor (alpha-2-thiol proteinase inhibitor) [contains: bradykinin]. [swissprot;acc:p01042]	KNG1
708	disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]	no value
709	ferritin light chain (ferritin l subunit). [swissprot;acc:p02792]	FTL
710	disks large-associated protein 4 (dap-4) (sap90/psd-95-associated protein 4) (sapap4) (psd-95/sap90 binding protein 4). [swissprot;acc:q9y2h0]	DLGAP4
711	tyrosyl-trna synthetase (ec 6.1.1.1) (tyrosyl--trna ligase) (tyrrs). [swissprot;acc:p54577]	YARS	232.468	245.048	1.05411
712	ferritin heavy polypeptide-like 17. [swissprot;acc:q9bxu8]	FTHL17	220.431	209.123	1.05407
713	dendritic cell protein. [refseq;acc:nm_006360]	EIF3M	223.121	211.685	1.05402
714	potential carboxypeptidase-like protein x2 precursor. [swissprot;acc:q8n436]	CPXM2
715	carboxypeptidase n catalytic chain precursor (ec 3.4.17.3) (arginine carboxypeptidase) (kininase 1) (serum carboxypeptidase n) (scpn) (anaphylatoxin inactivator) (plasma carboxypeptidase b). [swissprot;acc:p15169]	CPN1
716	cpz gene product. [refseq;acc:nm_003652]	CPZ
717	carboxypeptidase h precursor (ec 3.4.17.10) (cph) (carboxypeptidase e) (cpe) (enkephalin convertase) (prohormone processing carboxypeptidase). [swissprot;acc:p16870]	CPE
718	potential carboxypeptidase x precursor (ec 3.4.17.-) (metallocarboxypeptidase cpx-1). [swissprot;acc:q96sm3]	CPXM1
719	nucleolar protein nop56 (nucleolar protein 5a). [swissprot;acc:o00567]	NOL5A	247.769	235.074	1.054
720	60s acidic ribosomal protein p2. [swissprot;acc:p05387]	RPLP2	231.92	244.435	1.05396
721	exocyst complex component sec10 (hsec10). [swissprot;acc:o00471]	EXOC5	214.765	203.8	1.0538
722	trehalase precursor (ec 3.2.1.28) (alpha,alpha-trehalase) (alpha,alpha-trehalose glucohydrolase). [swissprot;acc:o43280]	TREH	217.952	206.902	1.05341
723	histone h3.3 (h3.a) (h3.b) (h3.3q). [swissprot;acc:p06351]	no value	244.842	232.577	1.05274
724	dj1099d15.1 (putative dnaj protein). [sptrembl;acc:q9h4j9]
725	mevalonate kinase (ec 2.7.1.36) (mk). [swissprot;acc:q03426]	MVK	235.296	247.673	1.0526
726	ftsj homolog 3; likely ortholog of mouse ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 3. [refseq;acc:nm_017647]	FTSJ3	244.495	232.419	1.05196
727	probable serine/threonine-protein kinase kiaa0537 (ec 2.7.1.-). [swissprot;acc:o60285]	NUAK1	208.873	219.71	1.05188
728	n-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase (ec 2.4.1.149) (poly-n-acetyllactosamine extension enzyme) (i-beta- 1,3-n-acetylglucosaminyltransferase) (ignt) (udp-glcnac:betagal beta- 1,3-n-acetylglucosaminyltransferase 6). [swissprot;acc:o43505]	B3GNT1	208.874	219.708	1.05187
729	huntingtin interacting protein e; huntingtin interactor protein e. [refseq;acc:nm_007076]	no value

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.