MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	red	Network Comparison Type	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 662 to 711 of 2060 in total

red  : 0
Network Comparison Type  : Subtracted
network_comparison  : 0
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type	Interaction Map
high mobility group protein 1-like 10 (hmg-1l10). [swissprot;acc:q9ugv6]	3144	HMG1L10	Ranked	High confidence
			Squared
			Rooted
high mobility group protein 2 (hmg-2). [swissprot;acc:p26583]	2856	HMGB2	Measured
			Ranked
			Squared
			Rooted
high mobility group protein 4 (hmg-4) (high mobility group protein 2a) (hmg-2a). [swissprot;acc:o15347]	3203	HMGB3	Measured
			Ranked
			Squared
			Rooted
high mobility group protein 4-like (hmg-4l). [swissprot;acc:q9uj13]	2787	HMG4L	Measured
			Ranked
			Squared
			Rooted
high-affinity cgmp-specific 3',5'-cyclic phosphodiesterase 9a (ec 3.1.4.17). [swissprot;acc:o76083]	2876	PDE9A	Measured
			Ranked
			Squared
			Rooted
high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9]	2863	no value	Measured
			Ranked
			Squared
			Rooted
histone deacetylase 3 (hd3) (rpd3-2). [swissprot;acc:o15379]	2813	HDAC3	Measured
			Ranked
			Squared
			Rooted
	5021		Ranked	Low confidence
	5022		Measured
			Squared
			Rooted
histone deacetylase 6 (hd6). [swissprot;acc:q9ubn7]	3152	HDAC6	Measured	High confidence
			Ranked
			Squared
			Rooted
histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	2784	HIST3H2A	Measured
			Ranked
			Squared
			Rooted
histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	2767	no value	Measured
			Ranked
			Squared
			Rooted
histone h2a.e (h2a/e). [swissprot;acc:q99878]	2765		Measured
			Ranked
			Squared
			Rooted
histone h2a.q (h2a/q) (h2a-gl101) (fragment). [swissprot;acc:q16777]	2769	HIST2H2AC	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.