MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Network Comparison Type	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

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Showing element 6358 to 6407 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	red	green	network_comparison
xpmc2 prevents mitotic catastrophe 2 homolog; xenopus prevents mitotic catastrophe 2 homolog. [refseq;acc:nm_020385]	2339	Subtracted	REXO4	209.326	208.357	0.969
xylulokinase homolog; xylulokinase (h. influenzae) homolog. [refseq;acc:nm_005108]	2475		XYLB	211.205	210.577	0.628
	2476	Divided				1.00298
yeast sec31p homolog. [refseq;acc:nm_014933]	1098	Subtracted	SEC31A	218.484	212.675	5.809
	1136	Divided				1.02731
yip1 interacting factor homolog; yip1p-interacting factor; putative rab5-interacting protein; putative transmembrane protein 54tmp. [refseq;acc:nm_020470]	1925	Subtracted	YIF1A	211.633	213.703	2.07
	1955	Divided				1.00978
yl-1 protein (transcription factor-like 1). [swissprot;acc:q15906]	1639		VPS72	194.516	197.364	1.01464
	1711	Subtracted				2.848
yme1-like 1 isoform 3; atp-dependent metalloprotease ftsh1 homolog. [refseq;acc:nm_014263]	495		YME1L1	222.146	237.393	15.247
	528	Divided				1.06864
z-protein (protein cgi-119) (s1r protein). [swissprot;acc:q9hc24]	1611	Subtracted	TMBIM4	217.446	214.2	3.246
	1626	Divided				1.01515
zasp protein (fragment). [sptrembl;acc:q9y4z3]	1951	Subtracted	LDB3	219.267	217.207	2.06
	1992	Divided				1.00948
zinc finger daz interacting protein 1. [refseq;acc:nm_014934]	2981		DZIP1	0.00001	0.00001	1
		Subtracted		0	0	0
zinc finger homeobox protein 1b (smad interacting protein 1) (smadip1) (hrihfb2411). [swissprot;acc:o60315]	2278	Divided	ZEB2	191.936	190.909	1.00538
	2320	Subtracted				1.027
zinc finger imprinted 2. [swissprot;acc:q9nzv7]	866		no value	269.96	278.232	8.272
	1063	Divided				1.03064
zinc finger protein 174 (aw-1). [swissprot;acc:q15697]	865	Subtracted	ZNF174	269.963	278.239	8.276
	1062	Divided				1.03066
zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022]	867	Subtracted	ZNF18	269.956	278.223	8.267
	1066	Divided				1.03062
zinc finger protein 198 (fused in myeloproliferative disorders protein) (rearranged in atypical myeloproliferative disorder protein). [swissprot;acc:q9ubw7]	2607	Subtracted	ZMYM2	224.891	225.195	0.304
	2630	Divided				1.00135
zinc finger protein 207. [swissprot;acc:o43670]	1605	Subtracted	ZNF207	221.934	218.658	3.276
	1633	Divided				1.01498
zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771]	873	Subtracted	ZNF213	269.954	278.217	8.263
	1072	Divided				1.03061
zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58]	868	Subtracted	ZNF215	269.956	278.223	8.267
	1067	Divided				1.03062
zinc finger protein 232. [swissprot;acc:q9uny5]	871	Subtracted	ZNF232	269.954	278.218	8.264
	1069	Divided				1.03061
zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028]	869	Subtracted	ZNF24	269.955	278.221	8.266
	1064	Divided				1.03062
zinc finger protein 258. [refseq;acc:nm_145310]	2600	Subtracted	ZMYM6	224.891	225.195	0.304
	2622	Divided				1.00135
zinc finger protein 261 (dxs6673e protein). [swissprot;acc:q14202]	2601	Subtracted	ZMYM3			0.304
	2623	Divided				1.00135
zinc finger protein 262; cell death inhibiting rna. [refseq;acc:nm_005095]	2602	Subtracted	ZMYM4			0.304
	2624	Divided				1.00135
zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6]	874	Subtracted	ZNF274	269.953	278.215	8.262
	1068	Divided				1.03061
zinc finger protein 277. [swissprot;acc:q9nrm2]	989	Subtracted	no value	236.679	243.679	7
	1087	Divided				1.02958
zinc finger protein 288 (dendritic-derived btb/poz zinc finger protein). [swissprot;acc:q9hc78]	2444		ZBTB20	206.086	206.753	1.00324
	2460	Subtracted				0.667
zinc finger protein 289, id1 regulated; likely ortholog of mouse zfp289. [refseq;acc:nm_032389]	2108		ZNF289	221.248	222.788	1.54

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.