MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Hugo	Gene	description	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 6141 to 6190 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	Network Comparison Type	red	green	network_comparison
3071	STK38	serine/threonine kinase 38; serine threonine protein kinase. [refseq;acc:nm_007271]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3072	PAK1IP1	pak1 interacting protein 1; pak1-interacting protein; pak/plc-interacting protein 1. [refseq;acc:nm_017906]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3073	RWDD1	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3074	NT5DC3	tu12b1-ty protein. [refseq;acc:nm_016575]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3075	USP5	ubiquitin carboxyl-terminal hydrolase 5 (ec 3.1.2.15) (ubiquitin thiolesterase 5) (ubiquitin-specific processing protease 5) (deubiquitinating enzyme 5) (isopeptidase t). [swissprot;acc:p45974]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3076	no value	placental protein 11 precursor (ec 3.4.21.-) (pp11). [swissprot;acc:p21128]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3077	H2AFJ	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3078	CREBL2	camp responsive element binding protein-like 2. [refseq;acc:nm_001310]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3079	CYP27B1	25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3080	no value	nucleosome assembly protein 1-like 4 (nucleosome assembly protein 2) (nap2). [swissprot;acc:q99733]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3081	PTPMT1	nadh-ubiquinone oxidoreductase 30 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-30kd) (ci-30kd). [swissprot;acc:o75489]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3082	CRYAB	alpha crystallin b chain (alpha(b)-crystallin) (rosenthal fiber component). [swissprot;acc:p02511]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3083	GLRB	glycine receptor beta chain precursor (glycine receptor 58 kda subunit). [swissprot;acc:p48167]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3084	MAP2K1IP1	mitogen-activated protein kinase kinase 1 interacting protein 1 (mek binding partner 1) (mp1) (pro2783). [swissprot;acc:q9uha4]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3085	UGT2B10	udp-glucuronosyltransferase 2b10 precursor, microsomal (ec 2.4.1.17) (udpgt). [swissprot;acc:p36537]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3086	no value	udp-glucuronosyltransferase 2b15 precursor, microsomal (ec 2.4.1.17) (udpgt) (udpgth-3) (hlug4). [swissprot;acc:p54855]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3087	ALDOC	fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3088	YWHAE	14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3089	PRKAR1A	camp-dependent protein kinase type i-alpha regulatory chain (tissue- specific extinguisher-1) (tse1). [swissprot;acc:p10644]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3090	EZH1	enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3091	MLX	transcription factor-like protein 4 (max-like bhlhzip protein) (bigmax protein) (mlx). [swissprot;acc:q9uh92]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3092	DRG2	developmentally regulated gtp-binding protein 2 (drg 2). [swissprot;acc:p55039]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3093	no value	ptd016 protein. [refseq;acc:nm_016125]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3094	UBE2S	ubiquitin-conjugating enzyme e2-24 kda (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2-epf5). [swissprot;acc:q16763]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
3095	C10orf137	erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.