MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	Value Type	network_comparison	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 62 to 111 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Interaction Map  : High confidence
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type
aldehyde dehydrogenase 7 (ec 1.2.1.5). [swissprot;acc:p43353]	3222	ALDH3B1	Ranked
			Squared
			Rooted
aldehyde dehydrogenase 8 (ec 1.2.1.5). [swissprot;acc:p48448]	2992	ALDH3B2	Measured
			Ranked
			Squared
			Rooted
aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]	2960	AOX1	Measured
			Ranked
			Squared
			Rooted
alpha crystallin a chain. [swissprot;acc:p02489]	2875	CRYAA	Measured
			Ranked
			Squared
			Rooted
alpha crystallin b chain (alpha(b)-crystallin) (rosenthal fiber component). [swissprot;acc:p02511]	3082	CRYAB	Measured
			Ranked
			Squared
			Rooted
alveolar soft part sarcoma chromosome region, candidate 1; aspl protein; renal cell carcinoma gene on chromosome 17; renal cell carcinoma, papillary, 17 gene; aspscr1/tfe3 fusion gene, included. [refseq;acc:nm_024083]	2829	ASPSCR1	Measured
			Ranked
			Squared
			Rooted
amyloid beta precursor protein-binding protein 2; amyloid beta precursor protein (cytoplasmic tail)-binding protein 2; protein interacting with app tail 1. [refseq;acc:nm_006380]	3191	APPBP2	Measured
			Ranked
			Squared
			Rooted
ariadne-2 protein homolog (ari-2) (triad1 protein) (ht005). [swissprot;acc:o95376]	2798	ARIH2	Measured
			Ranked
			Squared
			Rooted
atp synthase coupling factor 6, mitochondrial precursor (ec 3.6.3.14) (f6). [swissprot;acc:p18859]	2893	ATP5J	Measured
			Ranked
			Squared
			Rooted
atp synthase g chain, mitochondrial (ec 3.6.3.14) (atpase subunit g). [swissprot;acc:o75964]	2834	ATP5L	Measured
			Ranked
			Squared
			Rooted
au rna-binding protein/enoyl-coenzyme a hydratase precursor; au rna-binding protein/enoyl-coenzyme a hydratase; 3-methylglutaconyl-coa hydratase; mga type i. [refseq;acc:nm_001698]	2913	AUH	Measured
			Ranked
			Squared
			Rooted
ba203i16.1 (hypothetical protein kiaa0970). [sptrembl;acc:q9h1w1]	3117	FNDC3A	Measured
			Ranked
			Squared
			Rooted
ba528a10.3.2 (novel protein similar to kiaa0161, isoform 2) (fragment). [sptrembl;acc:q9bx39]	2968	RNF144B	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.