MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	Value Type	description	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 5908 to 5957 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	Network Comparison Type	red	network_comparison	green
2954	NDUFA9	nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	Subtracted	0	0	0
2955	FBN2	fibrillin 2 precursor. [swissprot;acc:p35556]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2956	SEC24B	protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2957	ENPEP	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2958	CNOT6L	ccr4-not transcription complex, subunit 6-like. [refseq;acc:nm_144571]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2959	no value	60s ribosomal protein l37a. [swissprot;acc:p12751]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2960	AOX1	aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2961	RAB1A	ras-related protein rab-1a (ypt1-related protein). [swissprot;acc:p11476]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2962	DYNC2LI1	dynein 2 light intermediate chain. [refseq;acc:nm_016008]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2963	RABGGTB	geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2964	SEMA6D	semaphorin 6d isoform 3 precursor. [refseq;acc:nm_153617]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2965	SLCO5A1	solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2966	PI15	protease inhibitor 15 preproprotein; 25 kda trypsin inhibitor. [refseq;acc:nm_015886]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2967	TAF8	taube nuss. [refseq;acc:nm_138572]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2968	RNF144B	ba528a10.3.2 (novel protein similar to kiaa0161, isoform 2) (fragment). [sptrembl;acc:q9bx39]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2969	TFAP2A	transcription factor ap-2 alpha (ap2-alpha) (activating enhancer- binding protein 2 alpha) (ap-2 transcription factor) (activator protein-2) (ap-2). [swissprot;acc:p05549]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2970	NOV	nov protein homolog precursor (novh) (nephroblastoma overexpressed gene protein homolog). [swissprot;acc:p48745]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2971	XPA	dna-repair protein complementing xp-a cells (xeroderma pigmentosum group a complementing protein). [swissprot;acc:p23025]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2972	NR5A1	steroidogenic factor 1 (stf-1) (sf-1) (steroid hormone receptor ad4bp) (fushi tarazu factor homolog 1). [swissprot;acc:q13285]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2973	ALDOB	fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2974	CDK9	cell division protein kinase 9 (ec 2.7.1.-) (serine/threonine-protein kinase pitalre) (c-2k). [swissprot;acc:p50750]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2975	KCTD3	potassium channel tetramerisation domain containing 3; ny-ren-45 antigen. [refseq;acc:nm_016121]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2976	CAB39	mo25 protein (cgi-66). [swissprot;acc:q9y376]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2977	CYP27A1	cytochrome p450 27, mitochondrial precursor (ec 1.14.-.-) (cytochrome p-450c27/25) (sterol 26-hydroxylase) (sterol 27-hydroxylase) (vitamin d(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase). [swissprot;acc:q02318]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2978	ITGA7	integrin alpha-7 precursor. [swissprot;acc:q13683]	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
2979	UGT2B28	udp-glucuronosyltransferase 2b28 precursor, microsomal (ec 2.4.1.17). [swissprot;acc:q9by64]	Divided	0.00001	1	0.00001

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.