MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	description	Gene	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 5908 to 5957 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Hugo	Network Comparison Type	red	green	network_comparison
2954	nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	NDUFA9	Subtracted	0	0	0
2955	fibrillin 2 precursor. [swissprot;acc:p35556]	FBN2	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2956	protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487]	SEC24B	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2957	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]	ENPEP	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2958	ccr4-not transcription complex, subunit 6-like. [refseq;acc:nm_144571]	CNOT6L	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2959	60s ribosomal protein l37a. [swissprot;acc:p12751]	no value	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2960	aldehyde oxidase (ec 1.2.3.1). [swissprot;acc:q06278]	AOX1	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2961	ras-related protein rab-1a (ypt1-related protein). [swissprot;acc:p11476]	RAB1A	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2962	dynein 2 light intermediate chain. [refseq;acc:nm_016008]	DYNC2LI1	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2963	geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	RABGGTB	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2964	semaphorin 6d isoform 3 precursor. [refseq;acc:nm_153617]	SEMA6D	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2965	solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	SLCO5A1	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2966	protease inhibitor 15 preproprotein; 25 kda trypsin inhibitor. [refseq;acc:nm_015886]	PI15	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2967	taube nuss. [refseq;acc:nm_138572]	TAF8	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2968	ba528a10.3.2 (novel protein similar to kiaa0161, isoform 2) (fragment). [sptrembl;acc:q9bx39]	RNF144B	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2969	transcription factor ap-2 alpha (ap2-alpha) (activating enhancer- binding protein 2 alpha) (ap-2 transcription factor) (activator protein-2) (ap-2). [swissprot;acc:p05549]	TFAP2A	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2970	nov protein homolog precursor (novh) (nephroblastoma overexpressed gene protein homolog). [swissprot;acc:p48745]	NOV	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2971	dna-repair protein complementing xp-a cells (xeroderma pigmentosum group a complementing protein). [swissprot;acc:p23025]	XPA	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2972	steroidogenic factor 1 (stf-1) (sf-1) (steroid hormone receptor ad4bp) (fushi tarazu factor homolog 1). [swissprot;acc:q13285]	NR5A1	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2973	fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	ALDOB	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2974	cell division protein kinase 9 (ec 2.7.1.-) (serine/threonine-protein kinase pitalre) (c-2k). [swissprot;acc:p50750]	CDK9	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2975	potassium channel tetramerisation domain containing 3; ny-ren-45 antigen. [refseq;acc:nm_016121]	KCTD3	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2976	mo25 protein (cgi-66). [swissprot;acc:q9y376]	CAB39	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2977	cytochrome p450 27, mitochondrial precursor (ec 1.14.-.-) (cytochrome p-450c27/25) (sterol 26-hydroxylase) (sterol 27-hydroxylase) (vitamin d(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase). [swissprot;acc:q02318]	CYP27A1	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2978	integrin alpha-7 precursor. [swissprot;acc:q13683]	ITGA7	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2979	udp-glucuronosyltransferase 2b28 precursor, microsomal (ec 2.4.1.17). [swissprot;acc:q9by64]	UGT2B28	Divided	0.00001	0.00001	1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.