MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Filtered	Gene	Value Type	Rank	Network Comparison Type	description	Interaction Map	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 101 to 150 of 77072 in total

Filtered  : 0
Value Type  : Measured

Rank	Network Comparison Type	description	Interaction Map	network_comparison	red	green
26	Divided	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]	High confidence	4.3268	153	662
		glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926]	Low confidence	3.04255	143	47
	Subtracted	block 23. [sptrembl;acc:q8nhw5]		626.74	4561.13	5187.87
		ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464]	High confidence	902.5	2965.5	2063
27	Divided	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	Low confidence	2.97183	105.5	35.5
		phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [swissprot;acc:p11086]	High confidence	4.10072	570	139
	Subtracted	baculoviral iap repeat-containing protein 5 (apoptosis inhibitor survivin) (apoptosis inhibitor 4). [swissprot;acc:o15392]		894	14357.1	13463.1
		candidate tumor suppressor protein. [refseq;acc:nm_020381]	Low confidence	589.67	2232	2821.67
28	Divided	beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]	High confidence	4.10072	570	139
		melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]	Low confidence	2.97183	105.5	35.5
	Subtracted	spectrin beta chain, brain 4 (spectrin, non-erythroid beta chain 4) (beta-v spectrin) (bspecv). [swissprot;acc:q9nrc6]	High confidence	874.45	5418.2	4543.75
		supervillin isoform 1; membrane-associated f-actin binding protein p205; archvillin. [refseq;acc:nm_003174]	Low confidence	589.67	2232	2821.67
29	Divided	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]		2.97183	105.5	35.5
		potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281]	High confidence	3.90833	111.278	434.911
	Subtracted	cytochrome c oxidase polypeptide viic, mitochondrial precursor (ec 1.9.3.1). [swissprot;acc:p15954]	Low confidence	582.8	20505.7	21088.5
		regulator of chromosome condensation (cell cycle regulatory protein). [swissprot;acc:p18754]	High confidence	849.19	3248.95	2399.76
30	Divided	dystrophin. [swissprot;acc:p11532]		3.82335	427.217	111.739
		melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]	Low confidence	2.97183	105.5	35.5
	Subtracted	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]	High confidence	837.72	3265.25	4102.97
		protein kinase, lysine deficient 3. [refseq;acc:nm_020922]	Low confidence	579.5	125	704.5
31	Divided	dok-like protein. [refseq;acc:nm_024872]	High confidence	3500000	35	0.00001
		hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]	Low confidence	2.97183	105.5	35.5
	Subtracted	adenomatous polyposis coli like. [refseq;acc:nm_005883]		570	2544.19	3114.19
		spectrin alpha chain, brain (spectrin, non-erythroid alpha chain) (alpha-ii spectrin) (fodrin alpha chain). [swissprot;acc:q13813]	High confidence	804	1833	2637
32	Divided	cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336]		3.25	598	184
		melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]	Low confidence	2.97183	105.5	35.5
	Subtracted	dead-box protein abstrakt homolog. [swissprot;acc:q9ujv9]		550.54	2476.1	3026.64
		mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]	High confidence	801	859	58
33	Divided	lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [refseq;acc:nm_003893]		3.15402	12.6208	39.8063
		melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	Low confidence	2.97183	105.5	35.5
	Subtracted	protein cgi-147. [swissprot;acc:q9y3e5]	High confidence	796.26	8396.12	9192.38
		scribble. [refseq;acc:nm_015356]	Low confidence	547.36	3697.8	4245.16
34	Divided	glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926]	High confidence	3.04255	143	47
		melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	Low confidence	2.97183	105.5	35.5
	Subtracted	acrc protein; putative nuclear protein. [refseq;acc:nm_052957]	High confidence	791.03	4131.06	3340.03
		peptide chain release factor 1, mitochondrial precursor (mrf-1). [swissprot;acc:o75570]	Low confidence	521.18	840.74	1361.92
35	Divided	adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236]	High confidence	2.99674	459.5	1377
		melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]	Low confidence	2.97183	105.5	35.5
	Subtracted	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]		509	153	662
		filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]	High confidence	705	1603	898
36	Divided	heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174]		2.80357	157	56
		melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	Low confidence	2.97183	105.5	35.5
	Subtracted	oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977]	High confidence	660.772	1586.07	925.298
		ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464]	Low confidence	484.19	1763.83	1279.64
37	Divided	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	High confidence	2.79409	334.401	934.348
		melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]	Low confidence	2.97183	105.5	35.5
	Subtracted	glutamate dehydrogenase 2, mitochondrial precursor (ec 1.4.1.3) (gdh). [swissprot;acc:p49448]		478.72	5931.43	5452.71
		wiskott-aldrich syndrome protein family member 3 (wasp-family protein member 3) (verprolin homology domain-containing protein 3). [swissprot;acc:q9upy6]	High confidence	652.25	5202.89	4550.64
38	Divided	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	Low confidence	2.97183	105.5	35.5
		zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623]	High confidence	2.65727	320.012	120.429

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.