MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Hugo	Network Comparison Type	Value Type	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 580 to 629 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
Filtered  : 1
green  : 0
network_comparison  : 0

Rank	description	Hugo	Value Type
2900	schwannomin interacting protein 1. [refseq;acc:nm_014575]	SCHIP1	Rooted
2901	casein kinase i, gamma 3 isoform (ec 2.7.1.-) (cki-gamma 3). [swissprot;acc:q9y6m4]	CSNK1G3	Measured
			Ranked
			Squared
			Rooted
2902	ubiquitin protein ligase. [refseq;acc:nm_130466]	UBE3B	Measured
			Ranked
			Squared
			Rooted
2903	protein transport protein sec24d (sec24-related protein d). [swissprot;acc:o94855]	SEC24D	Measured
			Ranked
			Squared
			Rooted
2904	6-pyruvoyl tetrahydrobiopterin synthase (ec 4.2.3.12) (ptps) (ptp synthase). [swissprot;acc:q03393]	PTS	Measured
			Ranked
			Squared
			Rooted
2905	integrin beta-1 precursor (fibronectin receptor beta subunit) (cd29 antigen) (integrin vla-4 beta subunit). [swissprot;acc:p05556]	ITGB1	Measured
			Ranked
			Squared
			Rooted
2906	thousand and one amino acid protein kinase. [refseq;acc:nm_004783]	TAOK2	Measured
			Ranked
			Squared
			Rooted
2907	fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]	ALDOA	Measured
			Ranked
			Squared
			Rooted
2908	serine/threonine-protein kinase chk1 (ec 2.7.1.-). [swissprot;acc:o14757]	CHEK1	Measured
			Ranked
			Squared
			Rooted
2909	nk6 transcription factor related, locus 2; nk homeobox family 6, b; glial and testis-specific homeobox protein; homeobox 6b. [refseq;acc:nm_177400]	NKX6-2	Measured
			Ranked
			Squared
			Rooted
2910	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	no value	Measured
			Ranked
			Squared
			Rooted
2911	bup protein. [refseq;acc:nm_012071]	COMMD3	Measured
			Ranked
			Squared
			Rooted
2912	inositol polyphosphate-5-phosphatase; phosphatidylinositol polyphosphate 5-phosphatase type iv; phosphatidylinositol (4,5) bisphosphate 5-phosphatase. [refseq;acc:nm_019892]	INPP5E	Measured
			Ranked
			Squared
			Rooted
2913	au rna-binding protein/enoyl-coenzyme a hydratase precursor; au rna-binding protein/enoyl-coenzyme a hydratase; 3-methylglutaconyl-coa hydratase; mga type i. [refseq;acc:nm_001698]	AUH	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.