MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 580 to 629 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
40s ribosomal protein s23. [swissprot;acc:p39028]	669	RPS23	Rooted	Subtracted	49.8325	45.2077	4.6248
	1965		Squared	Divided	12300.5	13441.9	1.09279
	2152		Measured		3560.63	3381.34	1.05302
	2416			Subtracted			179.29
	2493		Squared		12300.5	13441.9	1141.4
40s ribosomal protein s24 (s19). [swissprot;acc:p16632]	1009	RPS24		Divided	21492.5	24677.4	1.14819
	1144			Subtracted			3184.9
	1599		Measured	Divided	5184.45	5554.97	1.07147
	1657		Ranked	Subtracted	224.091	227.184	3.093
	1690			Divided			1.0138
	1860		Measured	Subtracted	5184.45	5554.97	370.52
	2393		Rooted	Divided	59.0426	59.9777	1.01584
	2411			Subtracted			0.9351
40s ribosomal protein s26. [swissprot;acc:p02383]	440	no value	Ranked		210.224	226.578	16.354
	454			Divided			1.07779
	806		Rooted		62.4161	58.6426	1.06435
	888			Subtracted			3.7735
	1655		Measured	Divided	5488.7	5131.89	1.06953
	1937			Subtracted			356.81
	2549		Squared		23172.9	22157.6	1015.3
	2578			Divided			1.04582
40s ribosomal protein s27 (metallopan-stimulin 1) (mps-1). [swissprot;acc:p42677]	1034		Ranked	Subtracted	229.442	235.974	6.532
	1102			Divided			1.02847
	1405		Squared		19596.4	21974.6	1.12136
	1699			Subtracted			2378.2
	2126		Measured	Divided	4806.33	5066.92	1.05422
	2253			Subtracted			260.59
	2682		Rooted	Divided	56.6826	56.8729	1.00336
	2689			Subtracted			0.1903
40s ribosomal protein s28. [swissprot;acc:p25112]	311		Squared		30682.9	38183.6	7500.7
	352			Divided			1.24446
	483		Measured	Subtracted	7161.14	8015.92	854.78
	700			Divided			1.11936
	1020		Rooted	Subtracted	70.4215	73.7627	3.3412
	1171			Divided			1.04745
	1982		Ranked		200.343	198.427	1.00966
	2000			Subtracted			1.916
40s ribosomal protein s29. [swissprot;acc:p30054]	198				241.849	267.642	25.793
	277			Divided			1.10665
	320		Rooted		50.2784	45.294	1.11005
	569			Subtracted			4.9844
	1756		Measured	Divided	3582.57	3357.6	1.067
	2128		Squared		12106.4	13163.1	1.08728
	2337		Measured	Subtracted	3582.57	3357.6	224.97
	2535		Squared		12106.4	13163.1	1056.7
40s ribosomal protein s3. [swissprot;acc:p23396]	270	RPS3	Ranked		241.612	265.119	23.507
	346			Divided			1.09729
	462		Rooted		50.6274	46.236	1.09498
	732			Subtracted			4.3914
	1980		Squared	Divided	12856.2	14048	1.0927

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.