MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 5786 to 5835 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	Network Comparison Type	red	green	network_comparison
2893	ATP5J	atp synthase coupling factor 6, mitochondrial precursor (ec 3.6.3.14) (f6). [swissprot;acc:p18859]	Subtracted	0	0	0
2894	GTF2E1	transcription initiation factor iie, alpha subunit (tfiie-alpha) (general transcription factor iie 56 kda subunit). [swissprot;acc:p29083]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2895	no value	ribose-phosphate pyrophosphokinase iii (ec 2.7.6.1) (phosphoribosyl pyrophosphate synthetase iii) (prs-iii). [swissprot;acc:p21108]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2896	BMP6	bone morphogenetic protein 6 precursor (bmp-6). [swissprot;acc:p22004]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2897	no value	serine/threonine kinase 38 like. [refseq;acc:nm_015000]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2898	CLEC4F	likely ortholog of mouse c-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 13; c-type lectin 13; likely ortholog of rat kupffer cell c-type lectin receptor. [refseq;acc:nm_173535]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2899	SPARCL1	sparc-like protein 1 precursor (high endothelial venule protein) (hevin) (mast 9). [swissprot;acc:q14515]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2900	SCHIP1	schwannomin interacting protein 1. [refseq;acc:nm_014575]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2901	CSNK1G3	casein kinase i, gamma 3 isoform (ec 2.7.1.-) (cki-gamma 3). [swissprot;acc:q9y6m4]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2902	UBE3B	ubiquitin protein ligase. [refseq;acc:nm_130466]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2903	SEC24D	protein transport protein sec24d (sec24-related protein d). [swissprot;acc:o94855]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2904	PTS	6-pyruvoyl tetrahydrobiopterin synthase (ec 4.2.3.12) (ptps) (ptp synthase). [swissprot;acc:q03393]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2905	ITGB1	integrin beta-1 precursor (fibronectin receptor beta subunit) (cd29 antigen) (integrin vla-4 beta subunit). [swissprot;acc:p05556]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2906	TAOK2	thousand and one amino acid protein kinase. [refseq;acc:nm_004783]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2907	ALDOA	fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2908	CHEK1	serine/threonine-protein kinase chk1 (ec 2.7.1.-). [swissprot;acc:o14757]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2909	NKX6-2	nk6 transcription factor related, locus 2; nk homeobox family 6, b; glial and testis-specific homeobox protein; homeobox 6b. [refseq;acc:nm_177400]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2910	no value	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2911	COMMD3	bup protein. [refseq;acc:nm_012071]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2912	INPP5E	inositol polyphosphate-5-phosphatase; phosphatidylinositol polyphosphate 5-phosphatase type iv; phosphatidylinositol (4,5) bisphosphate 5-phosphatase. [refseq;acc:nm_019892]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2913	AUH	au rna-binding protein/enoyl-coenzyme a hydratase precursor; au rna-binding protein/enoyl-coenzyme a hydratase; 3-methylglutaconyl-coa hydratase; mga type i. [refseq;acc:nm_001698]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2914	LACTB2	lactamase, beta 2. [refseq;acc:nm_016027]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2915	SLC25A37	mitochondrial solute carrier protein. [refseq;acc:nm_016612]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2916	PRPS1L1	ribose-phosphate pyrophosphokinase i (ec 2.7.6.1) (phosphoribosyl pyrophosphate synthetase i) (ppribp) (prs-i). [swissprot;acc:p09329]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2917	CCT6A	t-complex protein 1, zeta subunit (tcp-1-zeta) (cct-zeta) (cct-zeta-1) (tcp20) (htr3). [swissprot;acc:p40227]	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
2918	GBAS	nipsnap2 protein (glioblastoma amplified sequence). [swissprot;acc:o75323]	Divided	0.00001	0.00001	1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.