MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Network Comparison Type	Gene	Value Type	Hugo	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 558 to 607 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	red	network_comparison	green
androgen-induced 1; cgi-103 protein; androgen induced protein. [refseq;acc:nm_016108]	240	Divided	AIG1	227.357	1.11785	254.15
angiomotin like 2; leman coiled-coil protein; angiomotin-like protein 2. [refseq;acc:nm_016201]	2586		AMOTL2	213.422	1.00154	213.75
		Subtracted			0.328
angiomotin. [refseq;acc:nm_133265]	2585	Divided	AMOT		1.00154
		Subtracted			0.328
anillin, actin binding protein (scraps homolog, drosophila); anillin (drosophila scraps homolog), actin binding protein. [refseq;acc:nm_018685]	143	Divided	ANLN	59	1.20408	49
	773	Subtracted			10
ankyrin 2 (brain ankyrin) (ankyrin b) (ankyrin, nonerythroid). [swissprot;acc:q01484]	2516		ANK2	215.835	0.506	216.341
	2519	Divided			1.00234
ankyrin 3 (ank-3) (ankyrin g). [swissprot;acc:q12955]	2515	Subtracted	ANK3		0.506
	2518	Divided			1.00234
ankyrin-repeat family a protein 2 (rfxank-like 2). [swissprot;acc:q9h9e1]	793	Subtracted	ANKRA2	212.386	9.399	221.785
	805	Divided			1.04425
annexin a11 (annexin xi) (calcyclin-associated annexin 50) (cap-50) (56 kda autoantigen). [swissprot;acc:p50995]	1051	Subtracted	ANXA11	219.673	6.295	213.378
	1088	Divided			1.0295
annexin a7 (annexin vii) (synexin). [swissprot;acc:p20073]	1053	Subtracted	ANXA7	219.655	6.27	213.385
	1094	Divided			1.02938
antithrombin-iii precursor (atiii) (pro0309). [swissprot;acc:p01008]	2406	Subtracted	SERPINC1	218.2	0.784	218.984
	2418	Divided			1.00359
apg3p; pc3-96 protein. [refseq;acc:nm_022488]	169		ATG3	82.5916	1.18722	98.0548
	489	Subtracted			15.4632
apical-like protein (apxl protein). [swissprot;acc:q13796]	346		SHROOM2	231.492	20.356	211.136
	362	Divided			1.09641
apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576]	211	Subtracted	no value	237.302	24.892	212.41
	248	Divided			1.11719
apolipoprotein a-i binding protein; apoa-i binding protein. [refseq;acc:nm_144772]	1606		APOA1BP	207.916	1.0159	204.662
	1609	Subtracted			3.254
apolipoprotein b-100 precursor (apo b-100) [contains: apolipoprotein b-48 (apo b-48)]. [swissprot;acc:p04114]	2128		APOB	217.871	1.495	219.366
	2151	Divided			1.00686
apopain precursor (ec 3.4.22.-) (cysteine protease cpp32) (yama protein) (cpp-32) (caspase-3) (casp-3) (srebp cleavage activity 1) (sca-1). [swissprot;acc:p42574]	1166	Subtracted	CASP3	233.942	5.482	228.46
	1293	Divided			1.024
apoptosis antagonizing transcription factor. [refseq;acc:nm_012138]	929	Subtracted	AATF	243.045	7.623	235.422
	1014	Divided			1.03238
apoptosis inhibitor 5; fibroblast growth factor 2-interacting factor 2; api5-like 1. [refseq;acc:nm_006595]	1094	Subtracted	API5	218.484	5.809	212.675
	1132	Divided			1.02731
apoptosis inhibitor fksg2. [swissprot;acc:q9hau6]	1083	Subtracted	no value	217.99	5.867	212.123
	1111	Divided			1.02766
apoptosis-inducing factor (aif)-homologous mitochondrion-associated inducer of death; p53-responsive gene 3. [refseq;acc:nm_032797]	2418	Subtracted	AIFM2	210.205	0.751	209.454
	2421	Divided			1.00359
apurinic/apyrimidinic endonuclease 2; apurinic/apyrimidinic endonuclease-like 2; apex nuclease-like 2. [refseq;acc:nm_014481]	2523	Subtracted	APEX2	216.264	0.477	215.787
	2531	Divided			1.00221
aquaporin 4 (wch4) (mercurial-insensitive water channel) (miwc). [swissprot;acc:p55087]	2688	Subtracted	AQP4	188.191	0.145	188.046
	2690	Divided			1.00077
aquaporin 5. [swissprot;acc:p55064]		Subtracted	AQP5	188.192	0.144	188.048
	2692	Divided			1.00077
aquaporin-cd (aqp-cd) (water channel protein for renal collecting duct) (adh water channel) (aquaporin 2) (collecting duct water channel protein) (wch-cd). [swissprot;acc:p41181]	2689	Subtracted	AQP2	188.193	0.145
	2691	Divided			1.00077
aquaporin-chip (water channel protein for red blood cells and kidney proximal tubule) (aquaporin 1) (aqp-1) (urine water channel). [swissprot;acc:p29972]	2694		AQP1	188.223	1.00075	188.081
		Subtracted			0.142
arf gtpase-activating protein git1 (g protein-coupled receptor kinase- interactor 1). [swissprot;acc:q9y2x7]	1142		GIT1	216.729	5.605	222.334

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.