MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Network Comparison Type	Rank	Gene	Hugo	Value Type	description	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 551 to 600 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	Hugo	Value Type	description
2893	ATP5J	Squared	atp synthase coupling factor 6, mitochondrial precursor (ec 3.6.3.14) (f6). [swissprot;acc:p18859]
		Rooted
2894	GTF2E1	Measured	transcription initiation factor iie, alpha subunit (tfiie-alpha) (general transcription factor iie 56 kda subunit). [swissprot;acc:p29083]
		Ranked
		Squared
		Rooted
2895	no value	Measured	ribose-phosphate pyrophosphokinase iii (ec 2.7.6.1) (phosphoribosyl pyrophosphate synthetase iii) (prs-iii). [swissprot;acc:p21108]
		Ranked
		Squared
		Rooted
2896	BMP6	Measured	bone morphogenetic protein 6 precursor (bmp-6). [swissprot;acc:p22004]
		Ranked
		Squared
		Rooted
2897	no value	Measured	serine/threonine kinase 38 like. [refseq;acc:nm_015000]
		Ranked
		Squared
		Rooted
2898	CLEC4F	Measured	likely ortholog of mouse c-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 13; c-type lectin 13; likely ortholog of rat kupffer cell c-type lectin receptor. [refseq;acc:nm_173535]
		Ranked
		Squared
		Rooted
2899	SPARCL1	Measured	sparc-like protein 1 precursor (high endothelial venule protein) (hevin) (mast 9). [swissprot;acc:q14515]
		Ranked
		Squared
		Rooted
2900	SCHIP1	Measured	schwannomin interacting protein 1. [refseq;acc:nm_014575]
		Ranked
		Squared
		Rooted
2901	CSNK1G3	Measured	casein kinase i, gamma 3 isoform (ec 2.7.1.-) (cki-gamma 3). [swissprot;acc:q9y6m4]
		Ranked
		Squared
		Rooted
2902	UBE3B	Measured	ubiquitin protein ligase. [refseq;acc:nm_130466]
		Ranked
		Squared
		Rooted
2903	SEC24D	Measured	protein transport protein sec24d (sec24-related protein d). [swissprot;acc:o94855]
		Ranked
		Squared
		Rooted
2904	PTS	Measured	6-pyruvoyl tetrahydrobiopterin synthase (ec 4.2.3.12) (ptps) (ptp synthase). [swissprot;acc:q03393]
		Ranked
		Squared
		Rooted
2905	ITGB1	Measured	integrin beta-1 precursor (fibronectin receptor beta subunit) (cd29 antigen) (integrin vla-4 beta subunit). [swissprot;acc:p05556]
		Ranked
		Squared
		Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.