MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Network Comparison Type	Rank	Value Type	Hugo	Interaction Map	red	Filtered	network_comparison	green

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Showing element 551 to 600 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Network Comparison Type	Rank	Value Type	Hugo	red	network_comparison	green
40s ribosomal protein s19. [swissprot;acc:p39019]	Subtracted	1099	Measured	RPS19	4708.61	518.1	5226.71
		1478	Squared		18854.4	2686	21540.4
40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]	Divided	344	Ranked	no value	241.625	1.0973	265.136
		461	Rooted		50.6156	1.09501	46.2239
		1954	Squared		12789.3	1.09288	13977.2
		2242	Measured		3670.45	1.04723	3504.91
	Subtracted	269	Ranked		241.625	23.511	265.136
		731	Rooted		50.6156	4.3917	46.2239
		2450	Measured		3670.45	165.54	3504.91
		2468	Squared		12789.3	1187.9	13977.2
40s ribosomal protein s20. [swissprot;acc:p17075]	Divided	342	Ranked	RPS20	243.5	1.09737	267.21
		425	Rooted		50.0161	1.09849	45.5318
		1926	Squared		12452.6	1.09374	13619.9
		2211	Measured		3590.56	1.04907	3422.6
	Subtracted	251	Ranked		243.5	23.71	267.21
		707	Rooted		50.0161	4.4843	45.5318
		2436	Measured		3590.56	167.96	3422.6
		2485	Squared		12452.6	1167.3	13619.9
40s ribosomal protein s21. [swissprot;acc:p35265]	Divided	790	Ranked	RPS21	224.244	1.04578	234.511
		1048	Squared		20357.7	1.14717	23353.8
		2381	Rooted		58.6893	1.01623	57.7518
		2403	Measured		5078.5	1.03884	5275.76
	Subtracted	756	Ranked		224.244	10.267	234.511
		1236	Squared		20357.7	2996.1	23353.8
		2374	Measured		5078.5	197.26	5275.76
		2402	Rooted		58.6893	0.9375	57.7518
40s ribosomal protein s23. [swissprot;acc:p39028]	Divided	324	Ranked	RPS23	243.944	1.09941	268.195
		382	Rooted		49.8325	1.1023	45.2077
		1965	Squared		12300.5	1.09279	13441.9
		2152	Measured		3560.63	1.05302	3381.34
	Subtracted	234	Ranked		243.944	24.251	268.195
		669	Rooted		49.8325	4.6248	45.2077
		2416	Measured		3560.63	179.29	3381.34
		2493	Squared		12300.5	1141.4	13441.9
40s ribosomal protein s24 (s19). [swissprot;acc:p16632]	Divided	1009		RPS24	21492.5	1.14819	24677.4
		1599	Measured		5184.45	1.07147	5554.97
		1690	Ranked		224.091	1.0138	227.184
		2393	Rooted		59.0426	1.01584	59.9777
	Subtracted	1144	Squared		21492.5	3184.9	24677.4
		1657	Ranked		224.091	3.093	227.184
		1860	Measured		5184.45	370.52	5554.97
		2411	Rooted		59.0426	0.9351	59.9777
40s ribosomal protein s26. [swissprot;acc:p02383]	Divided	454	Ranked	no value	210.224	1.07779	226.578
		806	Rooted		62.4161	1.06435	58.6426
		1655	Measured		5488.7	1.06953	5131.89
		2578	Squared		23172.9	1.04582	22157.6
	Subtracted	440	Ranked		210.224	16.354	226.578
		888	Rooted		62.4161	3.7735	58.6426
		1937	Measured		5488.7	356.81	5131.89
		2549	Squared		23172.9	1015.3	22157.6

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.