MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Network Comparison Type	Value Type	Rank	Hugo	Interaction Map	red	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 525 to 574 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
Filtered  : 1
network_comparison  : 0
green  : 0

description	Value Type	Rank	Hugo	Interaction Map
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]	Measured	2831	FEN1	High confidence
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]	Measured	2907	ALDOA
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	Measured	2973	ALDOB
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972]	Measured	3087	ALDOC
	Ranked
	Squared
	Rooted
fyve-finger-containing rab5 effector protein rabenosyn-5. [refseq;acc:nm_022340]	Measured	2998	ZFYVE20
	Ranked
	Squared
	Rooted
g protein-coupled receptor 66. [refseq;acc:nm_006056]	Measured	2815	NMUR1
	Ranked
	Squared
	Rooted
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	Measured	5030	GGTLA4	Low confidence
	Ranked	5029
	Squared	5030
	Rooted
gamma-glutamyltransferase. [sptrembl;acc:q14390]	Measured	5053	GGTL4
	Ranked
	Squared
	Rooted
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]	Measured	5054	GGT1
	Ranked
	Squared
	Rooted
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]	Measured	5021	no value
	Ranked	5020
	Squared	5021
	Rooted
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]	Measured	5055	GGTLA1
	Ranked
	Squared
	Rooted
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	Measured	3101	no value	High confidence
	Ranked
	Squared
	Rooted
gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488]	Measured	3125	POFUT1
	Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.