MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	Value Type	network_comparison	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 501 to 550 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type	Interaction Map
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]	3228	SCYL3	Measured	High confidence
			Ranked
			Squared
			Rooted
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]	3181	ALDH3A2	Measured
			Ranked
			Squared
			Rooted
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]	3185	FECH	Measured
			Ranked
			Squared
			Rooted
fibrillin 1 precursor. [swissprot;acc:p35555]	2844	FBN1	Measured
			Ranked
			Squared
			Rooted
fibrillin 2 precursor. [swissprot;acc:p35556]	2955	FBN2	Measured
			Ranked
			Squared
			Rooted
fibrillin 3. [refseq;acc:nm_032447]	2939	FBN3	Measured
			Ranked
			Squared
			Rooted
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]	2831	FEN1	Measured
			Ranked
			Squared
			Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]	2907	ALDOA	Measured
			Ranked
			Squared
			Rooted
fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	2973	ALDOB	Measured
			Ranked
			Squared
			Rooted
fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972]	3087	ALDOC	Measured
			Ranked
			Squared
			Rooted
fyve-finger-containing rab5 effector protein rabenosyn-5. [refseq;acc:nm_022340]	2998	ZFYVE20	Measured
			Ranked
			Squared
			Rooted
g protein-coupled receptor 66. [refseq;acc:nm_006056]	2815	NMUR1	Measured
			Ranked
			Squared
			Rooted
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	5029	GGTLA4	Ranked	Low confidence
	5030		Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.