MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
40s ribosomal protein s13. [swissprot;acc:q02546]	1695	RPS13	Ranked	Subtracted	220.899	223.813	2.914
	1722			Divided			1.01319
	2348		Rooted		60.5137	61.6019	1.01798
	2361			Subtracted			1.0882
40s ribosomal protein s14 (pro2640). [swissprot;acc:p06366]	323	RPS14	Ranked		242.238	264.11	21.872
	386			Divided			1.09029
	530		Rooted		50.6537	46.6413	1.08603
	824			Subtracted			4.0124
	1823		Squared	Divided	13145.4	14424.1	1.09727
	2418			Subtracted			1278.7
	2436		Measured	Divided	3708.67	3584.47	1.03465
	2520			Subtracted			124.2
40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	219	no value	Ranked		242.339	266.986	24.647
	304			Divided			1.1017
	376		Rooted		50.2554	45.5688	1.10285
	651			Subtracted			4.6866
	1989		Squared	Divided	12388.6	13523.5	1.09161
	2067		Measured		3602.75	3411.18	1.05616
	2391			Subtracted			191.57
	2497		Squared		12388.6	13523.5	1134.9
40s ribosomal protein s15a. [swissprot;acc:p39027]	206	RPS15A	Ranked		241.411	266.414	25.003
	292			Divided			1.10357
	366		Rooted		50.5463	45.7763	1.1042
	615			Subtracted			4.77
	2008		Measured	Divided	3637.47	3435.61	1.05876
	2015		Squared		12467.2	13600.6	1.09091
	2368		Measured	Subtracted	3637.47	3435.61	201.86
	2502		Squared		12467.2	13600.6	1133.4
40s ribosomal protein s16. [swissprot;acc:p17008]	326	RPS16	Ranked		241.828	263.62	21.792
	391			Divided			1.09011
	534		Rooted		50.8036	46.8198	1.08509
	830			Subtracted			3.9838
	1784		Squared	Divided	13244.1	14564.4	1.09969
	2407			Subtracted			1320.3
	2448		Measured	Divided	3730.53	3611.05	1.03309
	2528			Subtracted			119.48
40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]	324	no value	Ranked		242.238	264.11	21.872
	387			Divided			1.09029
	531		Rooted		50.6537	46.6413	1.08603
	825			Subtracted			4.0124
	1824		Squared	Divided	13145.4	14424.1	1.09727
	2419			Subtracted			1278.7
	2437		Measured	Divided	3708.67	3584.47	1.03465
	2521			Subtracted			124.2
40s ribosomal protein s19. [swissprot;acc:p39019]	771	RPS19	Rooted	Divided	55.6817	59.3786	1.06639
	807		Measured		4708.61	5226.71	1.11003
	820		Ranked	Subtracted	234.025	224.958	9.067
	861			Divided			1.04031
	907		Rooted	Subtracted	55.6817	59.3786	3.6969
	1099		Measured		4708.61	5226.71	518.1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.