MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Value Type	Filtered	Rank	description	Gene	Network Comparison Type	Interaction Map	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 451 to 500 of 3730 in total

Value Type  : Ranked
Filtered  : 0
Network Comparison Type  : Divided
Interaction Map  : High confidence

Rank	description	green	red	network_comparison
451	cell adhesion molecule with homology to l1cam precursor; neural cell adhesion molecule; cell adhesion molecule l1-like; l1 cell adhesion molecule 2. [refseq;acc:nm_006614]	13737.2	14010.2	1.01987
452	neural cell adhesion molecule l1 precursor (n-cam l1) (cd171 antigen). [swissprot;acc:p32004]
453	transcription initiation factor tfiid 31 kda subunit (tafii-31) (tafii-32) (tafii32). [swissprot;acc:q16594]
454	lats homolog 1. [refseq;acc:nm_004690]	14204.8	13933.5	1.01947
455	sh3 domain-binding glutamic acid-rich-like protein 2 (fovea-associated sh3 domain binding protein). [swissprot;acc:q9ujc5]
456	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	16721.6	16416.1	1.01861
457	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]
458	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]
459	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	20495	20875	1.01854
460	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	20558	20914	1.01732
461	scratch; scratch 1. [refseq;acc:nm_031309]	12358.1	12164.9	1.01588
462	dj850e9.1 (novel c2h2 type zinc finger protein similar to drosophila scratch (scrt), slug and xenopus snail) (fragment). [sptrembl;acc:q9nq03]	12378.3	12189.6	1.01548
463	dj153g14.2 (possible ca binding protein similar to nefa) (fragment). [sptrembl;acc:q9ujn8]	5473.99	5558.06	1.01536
464	ba395l14.12 (novel protein similar to small nuclear ribonucleoprotein polypeptide a' (snrpa1)). [sptrembl;acc:q9nu36]	9928.08	10076.4	1.01494
465	transducin-like enhancer protein 1 (esg1). [swissprot;acc:q04724]	9620.66	9482.68	1.01455
466	aspartate beta-hydroxylase isoform b; junctin isoform 1; junctate; aspartyl/asparaginyl-beta-hydroxylase; peptide-aspartate beta-dioxygenase; humbug. [refseq;acc:nm_032468]	1521	1543	1.01446
467	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	20914	21205	1.01391
468	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
469	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
470	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
471	galectin-4 (lactose-binding lectin 4) (l-36 lactose binding protein) (l36lbp) (antigen ny-co-27). [swissprot;acc:p56470]	11463	11319.2	1.0127
472	peroxisomal acyl-coenzyme a thioester hydrolase 2a (ec 3.1.2.2) (peroxisomal long-chain acyl-coa thioesterase 2) (zap128). [swissprot;acc:p49753]	7165.6	7080.27	1.01205
473	cop9 signalosome complex subunit 1 (g protein pathway suppressor 1) (gps1 protein) (mfh protein). [swissprot;acc:q13098]	825	816	1.01103
474	lipocalin-interacting membrane receptor. [refseq;acc:nm_018113]	11167.6	11290.1	1.01097
475	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]	18500	18667	1.00903
476	atlastin; guanylate-binding protein 3. [refseq;acc:nm_015915]	8329	8403	1.00888
477	ubiquitin-conjugating enzyme e2-17 kda 3 (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2(17)kb 3). [swissprot;acc:p47986]	15780.2	15920	1.00886
478	3-ketoacyl-coa thiolase, peroxisomal precursor (ec 2.3.1.16) (beta- ketothiolase) (acetyl-coa acyltransferase) (peroxisomal 3-oxoacyl- coa thiolase). [swissprot;acc:p09110]	10243.1	10156.4	1.00854
479	aldehyde dehydrogenase 8 (ec 1.2.1.5). [swissprot;acc:p48448]	15031.7	15155.8	1.00826
480	uncharacterized bone marrow protein bm033. [refseq;acc:nm_018452]
481	uridine kinase-like 1. [swissprot;acc:q9nwz5]	11462.4	11554.3	1.00802
482	kinesin-like protein kif13b (kinesin-like protein gakin). [swissprot;acc:q9nqt8]	6205.67	6156.33	1.00801
483	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]	12127.5	12223.8	1.00794
484	protein c20orf45 (cgi-107). [swissprot;acc:q9y3b1]	11414.3	11489.7	1.00661
485	pepsin a precursor (ec 3.4.23.1). [swissprot;acc:p00790]	12542.3	12461.5	1.00648
486	huntingtin interacting protein c. [refseq;acc:nm_012272]	13288.3	13372.4	1.00633
487	survival motor neuron protein (component of gems 1) (gemin1). [swissprot;acc:q16637]	13159.3	13236.8	1.00589
488	heat shock factor binding protein 1. [swissprot;acc:o75506]	15127.8	15204.2	1.00505
489	likely ortholog of mouse shc sh2-domain binding protein 1. [refseq;acc:nm_024745]	8811.09	8854.04	1.00487
490	dna-directed rna polymerase i 16 kda polypeptide (ec 2.7.7.6) (rpa16). [swissprot;acc:q9y2s0]	10338.7	10388.7	1.00484
491	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	21880	21970	1.00411
492	swi/snf related, matrix associated, actin dependent regulator of chromatin subfamily d member 1 (swi/snf complex 60 kda subunit) (brg1- associated factor 60a). [swissprot;acc:q96gm5]	6829.74	6802.96	1.00394
493	dj470l14.3 (novel protein similar to the arp2/3 protein complex subunit p21-arc (arc21)). [sptrembl;acc:q9h5b6]	12041.7	11999.1	1.00355
494	signal recognition particle receptor alpha subunit (sr-alpha) (docking protein alpha) (dp-alpha). [swissprot;acc:p08240]	11959.4	11985.5	1.00218
495	26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	11748.1	11725.2	1.00195
496	vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670]	9411.49	9394	1.00186
497	sh2 domain binding protein 1; tpr-containing, sh2-binding phosphoprotein. [refseq;acc:nm_014633]	13718.2	13692.7
498	adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]	10248.3	10231.8	1.00161
499	inosine-5'-monophosphate dehydrogenase 2 (ec 1.1.1.205) (imp dehydrogenase 2) (impdh-ii) (impd 2). [swissprot;acc:p12268]	9069.58	9080.73	1.00123
500	huntingtin interacting protein e; huntingtin interactor protein e. [refseq;acc:nm_007076]	394	394	1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.