MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

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Showing element 480 to 529 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Interaction Map	red	green	network_comparison
adaptor-related protein complex 1, mu 1 subunit (mu-adaptin 1) (adaptor protein complex ap-1 mu-1 subunit) (golgi adaptor ha1/ap1 adaptin mu-1 subunit) (clathrin assembly protein assembly protein complex 1 medium chain 1) (clathrin coat assembly protein ap47) (clathrin coat associated protein ap47) (ap-mu chain family member mu1a). [swissprot;acc:q9bxs5]	1770	AP1M1	High confidence	221.082	223.778	1.01219
adaptor-related protein complex 1, mu 2 subunit (mu-adaptin 2) (adaptor protein complex ap-1 mu-2 subunit) (golgi adaptor ha1/ap1 adaptin mu-2 subunit) (clathrin assembly protein assembly protein complex 1 medium chain 2) (ap-mu chain family member mu1b). [swissprot;acc:q9y6q5]	551	AP1M2	Low confidence	205.768	199.453	1.03166
	1751		High confidence	221.185	223.97	1.01259
adenine phosphoribosyltransferase (ec 2.4.2.7) (aprt). [swissprot;acc:p07741]	1049	no value		211.449	217.998	1.03097
	2462		Low confidence	199.981	196.388	1.0183
adenomatous polyposis coli like. [refseq;acc:nm_005883]	161	APC2		222.34	235.547	1.0594
adenomatous polyposis coli protein (apc protein). [swissprot;acc:p25054]	160	APC		222.31	235.538	1.0595
adenosine deaminase (ec 3.5.4.4) (adenosine aminohydrolase). [swissprot;acc:p00813]	1075	no value		202.317	197.601	1.02387
adenosine kinase (ec 2.7.1.20) (ak) (adenosine 5'-phosphotransferase). [swissprot;acc:p55263]	2151	ADK		200.658	196.898	1.0191
	2563		High confidence	208.429	208.779	1.00168
adenosylhomocysteinase (ec 3.3.1.1) (s-adenosyl-l-homocysteine hydrolase) (adohcyase). [swissprot;acc:p23526]	1553	AHCY		215.389	211.833	1.01679
	1929		Low confidence	201.465	197.571	1.01971
adenovirus 5 e1a-binding protein (bs69 protein). [swissprot;acc:q15326]	2502	ZMYND11	High confidence	217.417	216.844	1.00264
	3417		Low confidence	202.077	199.041	1.01525
adenylate cyclase, type v (ec 4.6.1.1) (atp pyrophosphate-lyase) (adenylyl cyclase) (fragment). [swissprot;acc:o95622]	467	ADCY5	High confidence	248.152	267.226	1.07686
	3745		Low confidence	201.897	199.211	1.01348
adenylate cyclase, type vi (ec 4.6.1.1) (atp pyrophosphate-lyase) (ca(2+)-inhibitable adenylyl cyclase). [swissprot;acc:o43306]	466	ADCY6	High confidence	248.152	267.226	1.07686
	3744		Low confidence	201.897	199.211	1.01348
adenylate kinase isoenzyme 2, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p54819]	379	AK2	High confidence	241.509	264.163	1.0938
	3213		Low confidence	201.971	198.79	1.016
adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]	348	no value	High confidence	242.14	265.696	1.09728
	4467		Low confidence	208.138	210.017	1.00903
adenylosuccinate lyase (ec 4.3.2.2) (adenylosuccinase) (asl) (asase). [swissprot;acc:p30566]	1608	ADSL		199.691	195.607	1.02088
	2067		High confidence	193.226	191.639	1.00828
adenylosuccinate synthase-like 1. [refseq;acc:nm_152328]	1192	ADSSL1	Low confidence	199.02	194.529	1.02309
	1661		High confidence	204.437	201.551	1.01432
adenylosuccinate synthetase (ec 6.3.4.4) (imp--aspartate ligase) (adss) (ampsase). [swissprot;acc:p30520]	1200	ADSS	Low confidence	198.973	194.493	1.02303
	1665		High confidence	204.433	201.564	1.01423
adenylyl cyclase-associated protein 1 (cap 1). [swissprot;acc:q01518]	1701	CAP1	Low confidence	201.46	197.403	1.02055
	1850		High confidence	215.931	213.587	1.01097
adenylyl cyclase-associated protein 2 (cap 2). [swissprot;acc:p40123]	1699	CAP2	Low confidence	201.425	197.367	1.02056
	1895		High confidence	215.853	213.639	1.01036
adhesion regulating molecule 1 precursor (110 kda cell membrane glycoprotein) (gp110). [swissprot;acc:q16186]	2369	ADRM1		218.555	219.434	1.00402
	2525		Low confidence	203.221	199.602	1.01813
adipocyte plasma membrane-associated protein (bscv protein). [swissprot;acc:q9hdc9]	813	C20orf3	High confidence	212.386	221.785	1.04425
	3843		Low confidence	201.394	198.793	1.01308
adiponectin receptor 2. [refseq;acc:nm_024551]	104	ADIPOR2		219.277	204.212	1.07377
	185		High confidence	281.582	246.371	1.14292
adp,atp carrier protein, fibroblast isoform (adp/atp translocase 2) (adenine nucleotide translocator 2) (ant 2). [swissprot;acc:p05141]	1552	SLC25A5		225.159	221.424	1.01687
	1779		Low confidence	199.221	195.272	1.02022
adp,atp carrier protein, heart/skeletal muscle isoform t1 (adp/atp translocase 1) (adenine nucleotide translocator 1) (ant 1). [swissprot;acc:p12235]	1551	SLC25A4	High confidence	225.159	221.424	1.01687
	1772		Low confidence	199.226	195.276	1.02023
adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236]	1550	SLC25A6	High confidence	225.159	221.424	1.01687
	1780		Low confidence	199.201	195.256	1.0202
adp-ribose pyrophosphatase (ec 3.6.1.13) (adp-ribose diphosphatase) (adenosine diphosphoribose pyrophosphatase) (adpr-ppase) (adp-ribose phosphohydrolase) (nucleoside diphosphate-linked moiety x motif 9). [swissprot;acc:q9bw91]	2492	NUDT9		203.957	200.307	1.01822
adp-ribosylation factor 1. [swissprot;acc:p32889]	1229	ARF1		202.83	198.315	1.02277
	2128		High confidence	221.248	222.788	1.00696
adp-ribosylation factor 3. [swissprot;acc:p16587]	1164	ARF3	Low confidence	202.869	198.252	1.02329
	2130		High confidence	221.248	222.788	1.00696
adp-ribosylation factor 4. [swissprot;acc:p18085]	1165	ARF4	Low confidence	202.831	198.216	1.02328

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.