MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	Gene	Value Type	Rank	Hugo	Interaction Map	red	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 462 to 511 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
Filtered  : 1
network_comparison  : 0
green  : 0

description	Value Type	Rank	Hugo
ell-associated factor 2; uncharacterized bone marrow protein bm040; testosterone regulated apoptosis inducer and tumor suppressor. [refseq;acc:nm_018456]	Ranked	2921	EAF2
	Squared
	Rooted
elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]	Measured	3027	TSFM
	Ranked
	Squared
	Rooted
endosome-associated fyve-domain protein. [refseq;acc:nm_014733]	Measured	3200	ZFYVE16
	Ranked
	Squared
	Rooted
enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800]	Measured	3090	EZH1
	Ranked
	Squared
	Rooted
enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910]	Measured	3098	EZH2
	Ranked
	Squared
	Rooted
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	Measured	3177	LMAN1
	Ranked
	Squared
	Rooted
erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	Measured	3095	C10orf137
	Ranked
	Squared
	Rooted
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]	Measured	2868	SNORA67
	Ranked
	Squared
	Rooted
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]	Measured	2888	EIF4A2
	Ranked
	Squared
	Rooted
exocyst complex component exo70. [swissprot;acc:q9upt5]	Measured	2781	EXOC7
	Ranked
	Squared
	Rooted
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]	Measured	3228	SCYL3
	Ranked
	Squared
	Rooted
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]	Measured	3181	ALDH3A2
	Ranked
	Squared
	Rooted
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]	Measured	3185	FECH
	Ranked
	Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.