MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 451 to 500 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Interaction Map  : High confidence
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type
dynein 2 light intermediate chain. [refseq;acc:nm_016008]	2962	DYNC2LI1	Squared
			Rooted
dynein intermediate chain 1, axonemal (axonemal dynein intermediate chain 1). [swissprot;acc:q9ui46]	3029	DNAI1	Measured
			Ranked
			Squared
			Rooted
ecotropic virus integration 1 site protein. [swissprot;acc:q03112]	3170	EVI1	Measured
			Ranked
			Squared
			Rooted
ell-associated factor 2; uncharacterized bone marrow protein bm040; testosterone regulated apoptosis inducer and tumor suppressor. [refseq;acc:nm_018456]	2921	EAF2	Measured
			Ranked
			Squared
			Rooted
elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]	3027	TSFM	Measured
			Ranked
			Squared
			Rooted
endosome-associated fyve-domain protein. [refseq;acc:nm_014733]	3200	ZFYVE16	Measured
			Ranked
			Squared
			Rooted
enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800]	3090	EZH1	Measured
			Ranked
			Squared
			Rooted
enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910]	3098	EZH2	Measured
			Ranked
			Squared
			Rooted
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	3177	LMAN1	Measured
			Ranked
			Squared
			Rooted
erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	3095	C10orf137	Measured
			Ranked
			Squared
			Rooted
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]	2868	SNORA67	Measured
			Ranked
			Squared
			Rooted
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]	2888	EIF4A2	Measured
			Ranked
			Squared
			Rooted
exocyst complex component exo70. [swissprot;acc:q9upt5]	2781	EXOC7	Measured
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.