MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Network Comparison Type	Rank	Gene	Hugo	description	Value Type	Interaction Map	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 380 to 429 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
red  : 0
green  : 0

Rank	Hugo	description	Value Type
2850	CDK5	cell division protein kinase 5 (ec 2.7.1.-) (tau protein kinase ii catalytic subunit) (tpkii catalytic subunit) (serine/threonine protein kinase pssalre). [swissprot;acc:q00535]	Rooted
2851	ORC5L	origin recognition complex subunit 5. [swissprot;acc:o43913]	Measured
			Ranked
			Squared
			Rooted
2852	HIST1H2AA	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured
			Ranked
			Squared
			Rooted
2853	TIGD6	tigger transposable element derived 6. [refseq;acc:nm_030953]	Measured
			Ranked
			Squared
			Rooted
2854	NARG1	transcriptional coactivator tubedown-100 isoform 1; putative n-acetyltransferase; gastric cancer antigen ga19. [refseq;acc:nm_057175]	Measured
			Ranked
			Squared
			Rooted
2855	HPGD	15-hydroxyprostaglandin dehydrogenase [nad(+)] (ec 1.1.1.141) (pgdh). [swissprot;acc:p15428]	Measured
			Ranked
			Squared
			Rooted
2856	HMGB2	high mobility group protein 2 (hmg-2). [swissprot;acc:p26583]	Measured
			Ranked
			Squared
			Rooted
2857	PRKCD	protein kinase c, delta type (ec 2.7.1.-) (npkc-delta). [swissprot;acc:q05655]	Measured
			Ranked
			Squared
			Rooted
2858	RYK	tyrosine-protein kinase ryk precursor (ec 2.7.1.112). [swissprot;acc:p34925]	Measured
			Ranked
			Squared
			Rooted
2859	NKX6-1	homeobox protein nkx-6.1. [swissprot;acc:p78426]	Measured
			Ranked
			Squared
			Rooted
2860	no value	importin 9. [refseq;acc:nm_018085]	Measured
			Ranked
			Squared
			Rooted
2861	GNPDA2	glucosamine-6-phosphate isomerase. [refseq;acc:nm_138335]	Measured
			Ranked
			Squared
			Rooted
2862	SDC3	syndecan-3 (synd3). [swissprot;acc:o75056]	Measured
			Ranked
			Squared
			Rooted
2863	no value	high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.