MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Network Comparison Type	Rank	Value Type	Hugo	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 3658 to 3707 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Network Comparison Type	Rank	Hugo	red	network_comparison	green
neurotrimin precursor (hnt). [swissprot;acc:q9p121]	Subtracted	1446	no value	224.022	4.098	219.924
neurotrypsin precursor (ec 3.4.21.-) (motopsin) (leydin). [swissprot;acc:p56730]	Divided	1649	PRSS12	219.062	1.01445	215.942
	Subtracted	1641			3.12
neutral and basic amino acid transport protein rbat (b(0,+)-type amino acid transport protein) (nbat) (d2h). [swissprot;acc:q07837]	Divided	1419	SLC3A1	203.979	1.02084	208.229
	Subtracted	1423			4.25
nf-kappab inhibitor alpha (major histocompatibility complex enhancer- binding protein mad3) (i-kappa-b-alpha) (ikappabalpha) (ikb-alpha). [swissprot;acc:p25963]	Divided	2616	NFKBIA	202.821	1.00139	202.54
	Subtracted	2631			0.281
nf-kappab inhibitor beta (nf-kappa-bib) (i-kappa-b-beta) (ikappabbeta) (ikb-beta) (ikb-b) (thyroid receptor interacting protein 9) (tr- interacting protein 9). [swissprot;acc:q15653]	Divided	2653	NFKBIB	201.452	1.0011	201.674
	Subtracted	2659			0.222
nf-kappab inhibitor epsilon (nf-kappa-bie) (i-kappa-b-epsilon) (ikappabepsilon) (ikb-epsilon) (ikbe). [swissprot;acc:o00221]	Divided	2651	NFKBIE	201.37	1.00111	201.594
	Subtracted	2657			0.224
ngd5 protein homolog (cgi-53). [swissprot;acc:q9y366]	Divided	3133	IFT52	0.00001	1	0.00001
	Subtracted			0	0	0
nhp2-like protein 1 (high mobility group-like nuclear protein 2 homolog 1) ([u4/u6.u5] tri-snrnp 15.5 kda protein) (otk27). [swissprot;acc:p55769]	Divided	1622	NHP2L1	228.611	1.01521	225.185
	Subtracted	1594			3.426
nicotinamide nucleotide adenylyltransferase 3; pyridine nucleotide adenylyltransferase 3. [refseq;acc:nm_178177]	Divided	2301	NMNAT3	217.392	1.00509	218.498
	Subtracted	2285			1.106
nicotinate-nucleotide pyrophosphorylase [carboxylating] (ec 2.4.2.19) (quinolinate phosphoribosyltransferase [decarboxylating]) (qaprtase) (qprtase). [swissprot;acc:q15274]	Divided	2257	QPRT	212.563	1.00591	211.315
	Subtracted	2251			1.248
nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]	Divided	2649	no value	213.63	1.00114	213.874
	Subtracted	2644			0.244
nin one binding protein; adenocarcinoma antigen recognized by t lymphocytes 4. [refseq;acc:nm_014062]	Divided	2499	NOB1	231.414	1.00283	230.76
	Subtracted	2461			0.654
nipsnap1 protein. [swissprot;acc:q9bpw8]	Divided	2770	NIPSNAP1	0.00001	1	0.00001
	Subtracted			0	0	0
nipsnap2 protein (glioblastoma amplified sequence). [swissprot;acc:o75323]	Divided	2918	GBAS	0.00001	1	0.00001
	Subtracted			0	0	0
nitrilase 1. [refseq;acc:nm_005600]	Divided	2579	NIT1	213.422	1.00154	213.75
	Subtracted				0.328
nitrogen fixation cluster-like. [refseq;acc:nm_014301]	Divided	1269	ISCU	171.231	1.02425	167.177
	Subtracted	1467			4.054
nk6 transcription factor related, locus 2; nk homeobox family 6, b; glial and testis-specific homeobox protein; homeobox 6b. [refseq;acc:nm_177400]	Divided	2909	NKX6-2	0.00001	1	0.00001
	Subtracted			0	0	0
nnp-1 protein (novel nuclear protein 1) (nucleolar protein nop52) (nop52) (d21s2056e). [swissprot;acc:p56182]	Divided	526	RRP1	250.538	1.06884	234.401
	Subtracted	459			16.137
nonspecific lipid-transfer protein, mitochondrial precursor (nsl-tp) (sterol carrier protein 2) (scp-2) (sterol carrier protein x) (scp-x) (scpx). [swissprot;acc:p22307]	Divided	800	SCP2	221.965	1.04501	212.404
	Subtracted	777			9.561
nostrin. [refseq;acc:nm_052946]	Divided	162	NOSTRIN	209.299	1.19058	249.187
	Subtracted	106			39.888
nov protein homolog precursor (novh) (nephroblastoma overexpressed gene protein homolog). [swissprot;acc:p48745]	Divided	2970	NOV	0.00001	1	0.00001
	Subtracted			0	0	0
ns1-associated protein 1. [refseq;acc:nm_006372]	Divided	249	SYNCRIP	237.302	1.11719	212.41
	Subtracted	212			24.892
nuclear autoantigen sp-100 (speckled 100 kda) (nuclear dot-associated sp100 protein) (lysp100b). [swissprot;acc:p23497]	Divided	3184	SP100	0.00001	1	0.00001
	Subtracted			0	0	0
nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	Divided	147	no value	50.7983	1.2009	42.3003
	Subtracted	859			8.498
nuclear factor (erythroid-derived 2)-like 3; nf-e2-related factor 3. [refseq;acc:nm_004289]	Divided	2743	NFE2L3	198.278	1.00022	198.321
	Subtracted				0.043
nuclear factor erythroid 2 related factor 1 (nf-e2 related factor 1) (nfe2-related factor 1) (nuclear factor, erythroid derived 2, like 1) (transcription factor 11) (transcription factor hbz17) (transcription factor lcr-f1) (locus control region-factor 1). [swissprot;acc:q14494]	Divided	2742	NFE2L1		1.00022

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.