MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 351 to 400 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Interaction Map	red	green	network_comparison
70 kda wd-repeat tumor rejection antigen homolog. [swissprot;acc:p57737]	3659	CORO7	Low confidence	201.605	198.82	1.01401
78 kda glucose-regulated protein precursor (grp 78) (immunoglobulin heavy chain binding protein) (bip) (endoplasmic reticulum lumenal ca(2+) binding protein grp78). [swissprot;acc:p11021]	4037	HSPA5		206.348	204.01	1.01146
80 kda nuclear cap binding protein (ncbp 80 kda subunit) (cbp80). [swissprot;acc:q09161]	3969	NCBP1		202.356	199.945	1.01206
85 kda calcium-independent phospholipase a2 (ec 3.1.1.4) (ipla2) (cai- pla2) (group vi phospholipase a2) (gvi pla2). [swissprot;acc:o60733]	1195	PLA2G6		202.297	197.738	1.02306
9 kda protein. [swissprot;acc:p13994]	1988	CCDC130	High confidence	219.26	217.193	1.00952
	2931		Low confidence	204.222	200.808	1.017
a kinase anchor protein 1, mitochondrial precursor (protein kinase a anchoring protein 1) (prka1) (a-kinase anchor protein 149 kda) (akap 149) (dual specificity a-kinase anchoring protein 1) (d-akap-1) (spermatid a-kinase anchor protein 84) (s-akap84). [swissprot;acc:q92667]	2167	AKAP1		202.625	198.833	1.01907
a kindred of iglon. [refseq;acc:nm_173808]	215	NEGR1		199.671	209.654	1.05
	804		High confidence	212.386	221.785	1.04425
a-kinase anchor protein 5 (a-kinase anchor protein 79 kda) (akap 79) (camp-dependent protein kinase regulatory subunit ii high affinity binding protein) (h21). [swissprot;acc:p24588]	1602	AKAP5	Low confidence	206.235	202.009	1.02092
	2788		High confidence	0.00001	0.00001	1
a-raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (a-raf-1) (proto-oncogene pks). [swissprot;acc:p10398]	957	ARAF		129.913	134.399	1.03453
	4840		Low confidence	184.234	183.595	1.00348
aarf domain containing kinase 1. [refseq;acc:nm_020421]	1575	ADCK1		199.725	195.6	1.02109
	1733		High confidence	215.336	212.567	1.01303
aarf domain containing kinase 2; putative ubiquinone biosynthesis protein aarf. [refseq;acc:nm_052853]	1572	ADCK2	Low confidence	199.725	195.6	1.02109
	1731		High confidence	215.336	212.567	1.01303
aarf domain containing kinase 4. [refseq;acc:nm_024876]	1574	ADCK4	Low confidence	199.725	195.6	1.02109
	1732		High confidence	215.336	212.567	1.01303
abhydrolase domain containing protein 2 (protein phps1-2). [swissprot;acc:p08910]	1935	ABHD2		218.43	216.279	1.00995
	2521		Low confidence	201.076	197.494	1.01814
abl-interactor 2; abl-interacting protein 1 (sh3-containing protein); abl binding protein 3; arg protein tyrosine kinase-binding protein; abl-interactor protein 2b; similar to spectrin sh3 domain binding protein 1. [refseq;acc:nm_005759]	779	ABI2		202.48	197.229	1.02662
	1845		High confidence	217.077	214.702	1.01106
abl-philin 2. [refseq;acc:nm_032327]	3025	ZDHHC16	Low confidence	202.348	199.029	1.01668
acetyl-coa acetyltransferase, mitochondrial precursor (ec 2.3.1.9) (acetoacetyl-coa thiolase) (t2). [swissprot;acc:p24752]	2259	ACAT1		199.914	196.214	1.01886
	2306		High confidence	191.571	192.544	1.00508
acetyl-coa carboxylase 1 (ec 6.4.1.2) (acc-alpha) [includes: biotin carboxylase (ec 6.3.4.14)]. [swissprot;acc:q13085]	2143	ACACA	Low confidence	197.608	193.896	1.01914
	2319		High confidence	194.842	195.8	1.00492
acetyl-coa carboxylase 2 (ec 6.4.1.2) (acc-beta) [includes: biotin carboxylase (ec 6.3.4.14)]. [swissprot;acc:o00763]	2144	ACACB	Low confidence	197.602	193.891	1.01914
	2315		High confidence	194.825	195.787	1.00494
acetyl-coenzyme a acetyltransferase 2; acetoacetyl coenzyme a thiolase. [refseq;acc:nm_005891]	4559	ACAT2	Low confidence	201.714	200.117	1.00798
acetyl-coenzyme a synthetase, cytoplasmic (ec 6.2.1.1) (acetate--coa ligase) (acyl-activating enzyme) (acetyl-coa synthetase) (acs) (acecs). [swissprot;acc:q9nr19]	2039	ACSS2	High confidence	190.551	192.191	1.00861
	2376		Low confidence	199.85	196.211	1.01855
acetyl-coenzyme a transporter. [refseq;acc:nm_004733]	2713	SLC33A1		201.627	198.156	1.01752
acid ceramidase precursor (ec 3.5.1.23) (acylsphingosine deacylase) (n-acylsphingosine amidohydrolase) (ac) (putative 32 kda heart protein) (php32). [swissprot;acc:q13510]	1421	ASAH1	High confidence	207.076	211.391	1.02084
	2275		Low confidence	203.735	199.972	1.01882
acid sphingomyelinase-like phosphodiesterase 3a (ec 3.1.4.-) (asm-like phosphodiesterase 3a) (fragment). [swissprot;acc:q92484]	2956	SMPDL3A		201.732	198.377	1.01691
acid sphingomyelinase-like phosphodiesterase 3b precursor (ec 3.1.4.-) (asm-like phosphodiesterase 3b). [swissprot;acc:q92485]	2960	SMPDL3B
acidic 82 kda protein mrna. [refseq;acc:nm_014597]	4677	DNTTIP2		202.475	201.278	1.00595
acidic leucine-rich nuclear phosphoprotein 32 family member a (potent heat-stable protein phosphatase 2a inhibitor i1pp2a) (hla-dr associated protein i) (phapi) (acidic nuclear phosphoprotein pp32) (cerebellar leucine rich acidic nuclear protein). [swissprot;acc:p39687]	569	ANP32A		206.46	200.275	1.03088
acidic leucine-rich nuclear phosphoprotein 32 family member b (phapi2 protein) (silver-stainable protein ssp29) (acidic protein rich in leucines). [swissprot;acc:q92688]	572	ANP32B
acidic leucine-rich nuclear phosphoprotein 32 family member c (tumorigenic protein pp32r1). [swissprot;acc:o43423]	567	ANP32C
acidic leucine-rich nuclear phosphoprotein 32 family member d (tumorigenic protein pp32r2). [swissprot;acc:o95626]	570	ANP32D
aconitate hydratase, mitochondrial precursor (ec 4.2.1.3) (citrate hydro-lyase) (aconitase). [swissprot;acc:q99798]	1299	ACO2		200.342	195.959	1.02237
acrc protein; putative nuclear protein. [refseq;acc:nm_052957]	2101	ACRC	High confidence	211.71	213.27	1.00737
	2308		Low confidence	201.265	197.572	1.01869
actin binding lim protein 2. [refseq;acc:nm_032432]	660	ABLIM2	High confidence	229.072	216.576	1.0577
	820		Low confidence	208.488	203.181	1.02612
actin, alpha cardiac. [swissprot;acc:p04270]	3962	ACTC1		200.879	198.479	1.01209
actin, aortic smooth muscle (alpha-actin 2). [swissprot;acc:p03996]	3964	ACTA2		200.877	198.477

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.