MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 351 to 400 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

Rank	description	Hugo	Interaction Map	red	green	network_comparison
176	dna polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4). [swissprot;acc:q9nr33]	POLE4	High confidence	275.754	235.908	1.1689
	tumor endothelial marker 6; thyroid specific ptb domain protein; tensin 3. [refseq;acc:nm_022748]	TNS3	Low confidence	219.336	207.703	1.05601
177	dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]	NCBP2L	High confidence	229.406	196.695	1.1663
	ribonuclease p protein subunit p20 (ec 3.1.26.5) (rnasep protein p20) (hpop7). [swissprot;acc:o75817]	POP7	Low confidence	209.954	221.607	1.0555
178	3'(2'), 5'-bisphosphate nucleotidase 1; bisphosphate 3'-nucleotidase; bpntase; pap-inositol-1,4-phosphatase. [refseq;acc:nm_006085]	BPNT1
	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	no value	High confidence	226.887	194.72	1.1652
179	60s ribosomal protein l6 (tax-responsive enhancer element binding protein 107) (taxreb107) (neoplasm-related protein c140). [swissprot;acc:q02878]	RPL6	Low confidence	209.954	221.607	1.0555
	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	no value	High confidence	226.884	194.79	1.16476
180	protocadherin 16 precursor (cadherin 19) (cadherin fibroblast 1). [swissprot;acc:q96jq0]	DCHS1	Low confidence	218.925	207.441	1.05536
	tar dna-binding protein-43 (tdp-43). [swissprot;acc:q13148]	TARDBP	High confidence	256.228	298.438	1.16474
181	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]	STAMBPL1	Low confidence	196.362	206.979	1.05407
	b9 protein; likely ortholog of mouse endothelial precursor protein b9. [refseq;acc:nm_015681]	B9D1	High confidence	229.818	267.265	1.16294
182	histone acetyltransferase type b catalytic subunit (ec 2.3.1.48). [swissprot;acc:o14929]	HAT1		277.546	240.461	1.15422
	px serine/threonine kinase. [refseq;acc:nm_017771]	PXK	Low confidence	196.372	206.947	1.05385
183	20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298]	NCBP2	High confidence	228.306	198.011	1.153
	bromodomain adjacent to zinc finger domain protein 1a (atp-utilizing chromatin assembly and remodeling factor 1) (hacf1) (atp-dependent chromatin remodelling protein) (williams syndrome transcription factor-related chromatin remodeling factor 180) (wcrf180) (hwalp1) (chrac subunit acf1) (hspc317). [swissprot;acc:q9nrl2]	no value	Low confidence	196.372	206.947	1.05385
184	odd-skipped related 1; odz (odd oz/ten-m) related 1. [refseq;acc:nm_145260]	OSR1	High confidence	274.027	237.79	1.15239
	testis specific, 10. [refseq;acc:nm_025244]	TSGA10	Low confidence	196.373	206.946	1.05384
185	adiponectin receptor 2. [refseq;acc:nm_024551]	ADIPOR2	High confidence	281.582	246.371	1.14292
	f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755]	no value	Low confidence	212.589	201.755	1.0537
186	associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463]	STAMBP		196.381	206.921	1.05367
	filamin b, beta (actin binding protein 278); beta filamin; filamin 1 (actin-binding protein-280)-like; filamin b, beta (actin-binding protein-278); filamin b, beta. [refseq;acc:nm_001457]	FLNB	High confidence	226.582	198.444	1.14179
187	rev1-like; rev1 protein; rev1 (yeast homolog)- like. [refseq;acc:nm_016316]	REV1
	ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464]	no value	Low confidence	189.373	179.829	1.05307
188	protein arginine n-methyltransferase 1 (ec 2.1.1.-) (interferon receptor 1-bound protein 4). [swissprot;acc:q99873]	PRMT1	High confidence	226.582	198.444	1.14179
	ribosomal protein s6 kinase, 52kda, polypeptide 1; ribosomal protein s6 kinase, 52kd, polypeptide 1. [refseq;acc:nm_012424]	RPS6KC1	Low confidence	189.45	179.944	1.05283
189	axonemal dynein light intermediate polypeptide 1 (inner dynein arm light chain, axonemal) (hp28). [swissprot;acc:o14645]	DNALI1		214.779	204.039	1.05264
	protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22]	PRMT8	High confidence	226.582	198.444	1.14179
190	dimethylaniline monooxygenase [n-oxide forming] 5 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 5) (fmo 5) (dimethylaniline oxidase 5). [swissprot;acc:p49326]	FMO5	Low confidence	210.557	200.074	1.0524
	u1 small nuclear ribonucleoprotein 70 kda (u1 snrnp 70 kda) (snrnp70) (u1-70k). [swissprot;acc:p08621]	SNRP70	High confidence	226.582	198.444	1.14179
191	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]	no value
	oligopeptide transporter, kidney isoform (peptide transporter 2) (kidney h+/peptide cotransporter) (solute carrier family 15, member 2). [swissprot;acc:q16348]	SLC15A2	Low confidence	201.43	191.43	1.05224
192	membrane-associated nucleic acid binding protein. [refseq;acc:nm_018835]	RC3H2		217.341	206.571	1.05214
	musashi 2 isoform a. [refseq;acc:nm_138962]	MSI2	High confidence	227.491	199.458	1.14055
193	hbs1-like. [refseq;acc:nm_006620]	HBS1L	Low confidence	206.166	216.913	1.05213
	musashi 1. [refseq;acc:nm_002442]	MSI1	High confidence	227.491	199.458	1.14055
194	conserved oligomeric golgi complex subunit 5 (13s golgi transport complex 90 kda subunit) (gtc-90) (golgi transport complex 1). [swissprot;acc:q9up83]	COG5	Low confidence	215.723	205.046	1.05207
	nuclear protein ukp68. [refseq;acc:nm_024824]	ZC3H14	High confidence	227.491	199.458	1.14055
195	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-7 subunit. [swissprot;acc:o60262]	no value	Low confidence	211.679	222.623	1.0517
	huntingtin interacting protein c. [refseq;acc:nm_012272]	PRPF40B	High confidence	227.971	200.417	1.13748
196	forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	FOXP4		263.215	231.407	1.13745
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6]	GNG12	Low confidence	211.679	222.623	1.0517
197	60s ribosomal protein l27. [swissprot;acc:p08526]	RPL27		211.912	201.556	1.05138
	forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]	FOXP1	High confidence	263.215	231.407	1.13745
198	forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	FOXP3		263.191	231.394	1.13741
	heat-shock 20 kda like-protein p20. [swissprot;acc:o14558]	HSPB6	Low confidence	219.606	208.904	1.05123
199	alpha crystallin a chain. [swissprot;acc:p02489]	CRYAA		219.589	208.895	1.05119
	palmitoyl-protein thioesterase 2 precursor (ec 3.1.2.22) (palmitoyl- protein hydrolase 2) (ppt-2) (g14). [swissprot;acc:q9umr5]	EGFL8	High confidence	242.735	276.059	1.13729
200	alpha crystallin b chain (alpha(b)-crystallin) (rosenthal fiber component). [swissprot;acc:p02511]	CRYAB	Low confidence	219.543	208.868	1.05111
	egf-like-domain, multiple 7; neu1 protein. [refseq;acc:nm_016215]	EGFL7	High confidence	242.718	276.018	1.1372

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.