MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 3101 to 3150 of 3228 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
red  : 0.00001
green  : 0.00001
network_comparison  : 1

Rank	description	Hugo
3101	gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	no value
3102	protein cgi-140 (protein ptd008) (my006 protein). [swissprot;acc:q9y284]	C19orf56
3103	dna ligase i (ec 6.5.1.1) (polydeoxyribonucleotide synthase [atp]). [swissprot;acc:p18858]	LIG1
3104	glioma tumor suppressor candidate region gene 2 protein (p60). [swissprot;acc:q9nzm5]	SNORD23
3105	transforming growth factor beta 1 precursor (tgf-beta 1). [swissprot;acc:p01137]	TGFB1
3106	prostate tumor overexpressed gene 1; prostate tumor over expressed gene 1. [refseq;acc:nm_017432]	PTOV1
3107	lyl-1 protein (lymphoblastic leukemia derived sequence 1). [swissprot;acc:p12980]	LYL1
3108	sorting nexin 16. [swissprot;acc:p57768]	SNX16
3109	wnt1 inducible signaling pathway protein 1 isoform 1 precursor; wnt-1 signaling pathway protein 1; wnt1 signaling pathway protein 1; wnt-1 inducible signaling pathway protein 1. [refseq;acc:nm_003882]	WISP1
3110	ras-related protein rab-2a. [swissprot;acc:p08886]	RAB2A
3111	serine/threonine protein kinase 3 (ec 2.7.1.37) (ste20-like kinase mst2) (mst-2) (mammalian ste20-like protein kinase 2) (serine/threonine protein kinase krs-1). [swissprot;acc:q13188]	STK3
3112	ras-related protein rab-11a (rab-11) (24kg) (yl8). [swissprot;acc:p24410]	RAB11A
3113	nuclear transport factor 2 (ntf-2) (placental protein 15) (pp15). [swissprot;acc:p13662]	NUTF2
3114	regulatory protein tsc-22 (tgfb stimulated clone 22 homolog). [swissprot;acc:q15714]	TSC22D1
3115	serine/threonine protein kinase 24 (ec 2.7.1.37) (ste20-like kinase mst3) (mst-3) (mammalian ste20-like protein kinase 3). [swissprot;acc:q9y6e0]	STK24
3116	mo25-like protein. [swissprot;acc:q9h9s4]	CAB39L
3117	ba203i16.1 (hypothetical protein kiaa0970). [sptrembl;acc:q9h1w1]	FNDC3A
3118	spermine synthase (ec 2.5.1.22) (spermidine aminopropyltransferase) (spmsy). [swissprot;acc:p52788]	SMS
3119	rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150]	no value
3120	sex comb on midleg-like 2; sex comb on midleg like 2. [refseq;acc:nm_006089]	SCML2
3121	glycine receptor alpha-2 chain precursor. [swissprot;acc:p23416]	GLRA2
3122	ribose-phosphate pyrophosphokinase ii (ec 2.7.6.1) (phosphoribosyl pyrophosphate synthetase ii) (ppribp) (prs-ii). [swissprot;acc:p11908]	PRPS2
3123	vesicle-associated membrane protein-associated protein a (vamp- associated protein a) (vamp-a) (vap-a) (33 kda vamp-associated protein) (vap-33). [swissprot;acc:q9p0l0]	VAPA
3124	sam domain and hd domain-containing protein 1 (dendritic cell-derived ifng-induced protein) (dcip) (monocyte protein 5) (mop-5). [swissprot;acc:q9y3z3]	SAMHD1
3125	gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488]	POFUT1
3126	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	PLCB4
3127	protein transport protein sec23b (sec23-related protein b). [swissprot;acc:q15437]	SEC23B
3128	bone morphogenetic protein 7 precursor (bmp-7) (osteogenic protein 1) (op-1). [swissprot;acc:p18075]	BMP7
3129	cleavage stimulation factor, 50 kda subunit (cstf 50 kda subunit) (cf-1 50 kda subunit). [swissprot;acc:q05048]	CSTF1
3130	prefoldin subunit 4 (protein c-1). [swissprot;acc:q9nqp4]	PFDN4
3131	protein c20orf24 (rab5-interacting protein) (rip5) (pnas-11). [swissprot;acc:q9buv8]	C20orf24
3132	r3h domain (binds single-stranded nucleic acids) containing-like. [refseq;acc:nm_178491]	R3HDML
3133	ngd5 protein homolog (cgi-53). [swissprot;acc:q9y366]	IFT52
3134	rab geranylgeranyltransferase alpha subunit (ec 2.5.1.-) (rab geranyl- geranyltransferase alpha subunit) (rab gg transferase alpha) (rab ggtase alpha). [swissprot;acc:q92696]	RABGGTA
3135	protein transport protein sec23a (sec23-related protein a). [swissprot;acc:q15436]	SEC23A
3136	vaccinia related kinase 1; vaccinia-related kinase-1. [refseq;acc:nm_003384]	VRK1
3137	serine/threonine-protein kinase kkialre (ec 2.7.1.-) (cyclin-dependent kinase-like 1). [swissprot;acc:q00532]	CDKL1
3138	hcdi protein. [refseq;acc:nm_020195]	C14orf124
3139	bromodomain-containing protein 1 (br140-like protein). [swissprot;acc:o95696]	BRD1
3140	myosin heavy chain, nonmuscle type a (cellular myosin heavy chain, type a) (nonmuscle myosin heavy chain-a) (nmmhc-a). [swissprot;acc:p35579]	MYH9
3141	tubulin tyrosine ligase-like protein 1. [swissprot;acc:o95922]	TTLL1
3142	protein kinase c and casein kinase substrate in neurons protein 2. [swissprot;acc:q9unf0]	PACSIN2
3143	prkca-binding protein (protein kinase c-alpha binding protein) (protein interacting with c kinase 1). [swissprot;acc:q9nrd5]	PICK1
3144	high mobility group protein 1-like 10 (hmg-1l10). [swissprot;acc:q9ugv6]	HMG1L10
3145	beta-ureidopropionase (ec 3.5.1.6) (beta-alanine synthase) (n-carbamoyl-beta-alanine amidohydrolase) (bup-1). [swissprot;acc:q9ubr1]	UPB1
3146	putative nadh oxidoreductase complex i subunit homolog. [sptrembl;acc:q96q80]	DERL3
3147	3 beta-hydroxy-delta 5-c27-steroid oxidoreductase. [refseq;acc:nm_025193]	HSD3B7
3148	muts protein homolog 5. [swissprot;acc:o43196]	no value
3149	bromodomain and phd finger-containing protein 3 (fragment). [swissprot;acc:q9uld4]	BRPF3
3150	cysteine-rich secretory protein-3 precursor (crisp-3) (sgp28 protein). [swissprot;acc:p54108]	CRISP3

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.