MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 3101 to 3150 of 8289 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1

Rank	Hugo	description	Interaction Map	red	green	network_comparison
1551	SLC25A4	adp,atp carrier protein, heart/skeletal muscle isoform t1 (adp/atp translocase 1) (adenine nucleotide translocator 1) (ant 1). [swissprot;acc:p12235]	High confidence	225.159	221.424	1.01687
	ZNHIT3	thyroid receptor interacting protein 3 (trip-3) (fragment). [swissprot;acc:q15649]	Low confidence	201.491	197.313	1.02117
1552	HOXA6	homeobox protein hox-a6 (hox-1b). [swissprot;acc:p31267]		203.119	198.908
	SLC25A5	adp,atp carrier protein, fibroblast isoform (adp/atp translocase 2) (adenine nucleotide translocator 2) (ant 2). [swissprot;acc:p05141]	High confidence	225.159	221.424	1.01687
1553	ABCD1	adrenoleukodystrophy protein (aldp). [swissprot;acc:p33897]	Low confidence	202.418	206.704	1.02117
	AHCY	adenosylhomocysteinase (ec 3.3.1.1) (s-adenosyl-l-homocysteine hydrolase) (adohcyase). [swissprot;acc:p23526]	High confidence	215.389	211.833	1.01679
1554	CTBP1	c-terminal binding protein 1 (ctbp1). [swissprot;acc:q13363]		196.215	193.018	1.01656
	RAB6B	ras-related protein rab-6b. [swissprot;acc:q9nrw1]	Low confidence	200.567	196.41	1.02116
1555	ATP6V1G3	vacuolar atp synthase subunit g 3 (ec 3.6.3.14) (v-atpase g subunit 3) (vacuolar proton pump g subunit 3) (v-atpase 13 kda subunit 3). [swissprot;acc:q96lb4]		202.345	198.152
	PASK	pas domain containing serine/threonine kinase; pas-serine/threonine kinase. [refseq;acc:nm_015148]	High confidence	196.192	192.996	1.01656
1556	no value	selenoprotein t. [swissprot;acc:q9nzj3]	Low confidence	205.836	201.572	1.02115
	BCL6	b-cell lymphoma 6 protein (bcl-6) (zinc finger protein 51) (laz-3 protein) (bcl-5). [swissprot;acc:p41182]	High confidence	196.192	192.996	1.01656
1557	SNAI2	zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623]
	TDH	l-threonine dehydrogenase; l-threonine 3-dehydrogenase. [refseq;acc:nm_152566]	Low confidence	205.836	201.572	1.02115
1558	CTBP2	c-terminal binding protein 2 (ctbp2). [swissprot;acc:p56545]	High confidence	196.171	192.977	1.01655
	RAB6C	ras-related protein rab-6a (rab-6). [swissprot;acc:p20340]	Low confidence	200.545	196.394	1.02114
1559	BCL6B	b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [refseq;acc:nm_181844]	High confidence	196.191	192.996	1.01655
	ZNF330	nucleolar cysteine-rich protein; zinc finger autoantigen 330. [refseq;acc:nm_014487]	Low confidence	205.98	201.716	1.02114
1560	GATAD2A	p66 alpha. [refseq;acc:nm_017660]	High confidence	167.687	170.455	1.01651
	HAS2	hyaluronan synthase 2 (ec 2.4.1.212) (hyaluronate synthase 2) (hyaluronic acid synthase 2) (ha synthase 2). [swissprot;acc:q92819]	Low confidence	197.747	193.656	1.02113
1561	CTDSP2	nuclear lim interactor-interacting factor 2 (nli-interacting factor 2) (protein os-4). [swissprot;acc:o14595]		201.534	197.366	1.02112
	GATAD2B	transcription repressor p66 beta component of the mecp1 complex. [refseq;acc:nm_020699]	High confidence	167.687	170.455	1.01651
1562	no value	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]
	NFKBIE	nf-kappab inhibitor epsilon (nf-kappa-bie) (i-kappa-b-epsilon) (ikappabepsilon) (ikb-epsilon) (ikbe). [swissprot;acc:o00221]	Low confidence	199.989	195.852	1.02112
1563	ATP5C1	atp synthase gamma chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p36542]	High confidence	218.277	214.739	1.01648
	HAS1	hyaluronan synthase 1 (ec 2.4.1.212) (hyaluronate synthase 1) (hyaluronic acid synthase 1) (ha synthase 1) (huhas1). [swissprot;acc:q92839]	Low confidence	197.752	193.661	1.02112
1564	ATP5O	atp synthase oligomycin sensitivity conferral protein, mitochondrial precursor (ec 3.6.3.14) (oscp). [swissprot;acc:p48047]	High confidence	218.277	214.739	1.01648
	HAS3	hyaluronan synthase 3 (ec 2.4.1.212) (hyaluronate synthase 3) (hyaluronic acid synthase 3) (ha synthase 3). [swissprot;acc:o00219]	Low confidence	197.74	193.65	1.02112
1565	BCL3	b-cell lymphoma 3-encoded protein (bcl-3 protein). [swissprot;acc:p20749]		199.975	195.839
	EIF3K	eukaryotic translation initiation factor 3 subunit 11 (eif-3 p25) (eif3k) (muscle specific gene m9 protein) (ptd001) (hspc029) (arg134). [swissprot;acc:q9ubq5]	High confidence	221.128	224.767	1.01646
1566	CTDSPL	nuclear lim interactor-interacting factor 1 (nli-interacting factor 1) (nif-like protein) (ya22 protein) (hya22). [swissprot;acc:o15194]	Low confidence	201.54	197.374	1.02111
	SLMO1	erythroid differentiation and denucleation factor 1. [swissprot;acc:o60584]	High confidence	221.128	224.767	1.01646
1567	BBS7	bardet-biedl syndrome 7 protein isoform a; bbs2-like 1. [refseq;acc:nm_176824]
	NFKB1	nuclear factor nf-kappa-b p105 subunit (dna-binding factor kbf1) (ebp- 1) [contains: nuclear factor nf-kappa-b p50 subunit]. [swissprot;acc:p19838]	Low confidence	199.973	195.838	1.02111
1568	no value	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	High confidence	221.128	224.767	1.01646
	NFKBIB	nf-kappab inhibitor beta (nf-kappa-bib) (i-kappa-b-beta) (ikappabbeta) (ikb-beta) (ikb-b) (thyroid receptor interacting protein 9) (tr- interacting protein 9). [swissprot;acc:q15653]	Low confidence	199.973	195.838	1.02111
1569	no value	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	High confidence	221.128	224.767	1.01646
	NFKB2	nuclear factor nf-kappa-b p100/p49 subunits (h2tf1) (oncogene lyt-10) (lyt10) [contains: nuclear factor nf-kappa-b p52 subunit]. [swissprot;acc:q00653]	Low confidence	199.973	195.838	1.02111
1570	CABC1	chaperone-activity of bc1 complex-like, mitochondrial precursor (chaperone-abc1-like). [swissprot;acc:q8ni60]		199.725	195.6	1.02109
	SLMO2	protein c20orf45 (cgi-107). [swissprot;acc:q9y3b1]	High confidence	221.128	224.767	1.01646
1571	EIF3EIP	eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [swissprot;acc:q9y262]
	PDCL	phosducin-like protein (phlp). [swissprot;acc:q13371]	Low confidence	203.614	199.408	1.02109
1572	ADCK2	aarf domain containing kinase 2; putative ubiquinone biosynthesis protein aarf. [refseq;acc:nm_052853]		199.725	195.6
	RBM7	putative rna-binding protein 7 (rna binding motif protein 7). [swissprot;acc:q9y580]	High confidence	221.128	224.767	1.01646
1573	ATP8A1	potential phospholipid-transporting atpase ia (ec 3.6.3.1) (chromaffin granule atpase ii) (atpase class i type 8a member 1). [swissprot;acc:q9y2q0]	Low confidence	201.121	196.967	1.02109
	R3HDM1	r3h domain protein 1. [swissprot;acc:q15032]	High confidence	218.105	214.573	1.01646
1574	ADCK4	aarf domain containing kinase 4. [refseq;acc:nm_024876]	Low confidence	199.725	195.6	1.02109
	TMF1	tata element modulatory factor (tmf). [swissprot;acc:p82094]	High confidence	222.585	218.982	1.01645
1575	ADCK1	aarf domain containing kinase 1. [refseq;acc:nm_020421]	Low confidence	199.725	195.6	1.02109
	SCYL1	scy1-like 1; telomerase regulation-associated protein; ht019 protein; telomerase regulation-associated protein; n-terminal kinase-like protein; teratoma-associated tyrosine kinase; n-terminal kinase-like. [refseq;acc:nm_020680]	High confidence	222.585	218.982	1.01645

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.