MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	description	Network Comparison Type	Rank	Interaction Map	Value Type	red	green	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Rank	Interaction Map	Value Type	red	green	Filtered	network_comparison
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	18	High confidence	Ranked	185.678	245.247	1	1.32082
	37		Measured	334.401	934.348	0	2.79409
			Squared	101.05	1034.13		10.2338
	53		Rooted	11.844	18.0183		1.5213
	60		Measured	4489.19	2765.82	1	1.6231
	64		Rooted	63.8686	47.2654		1.35128
	131	Low confidence	Measured	645.504	851.77	0	1.31954
	146		Squared	775.72	1268.51		1.63527
	242	High confidence	Ranked	15260.6	13895.8		1.09822
	245		Squared	8875.01	6768.05	1	1.31131
	537	Low confidence	Rooted	16.298	17.0804	0	1.04801
	629		Ranked	13205.3	13590.3		1.02915
	1119		Squared	43628.5	41688.5	1	1.04654
	4130		Ranked	199.383	201.5		1.01062
	4914		Measured	7853.62	7900.54		1.00597
			Rooted	71.9496	72.6287		1.00944
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	295	High confidence	Squared	30807.7	39351.7		1.27733
	509		Measured	7551.8	8630.06		1.14278
	805		Rooted	74.3557	79.1513		1.0645
	885	Low confidence	Measured	8255.95	8585.64		1.03993
	1038	High confidence	Ranked	186.741	181.041		1.03148
	1092	Low confidence	Rooted	73.5001	76.3375		1.0386
	1328		Ranked	198.342	194.038		1.02218
	4562		Squared	46617.7	45736		1.01928
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	294	High confidence		30826.5	39383.9		1.2776
	508		Measured	7556.75	8636.87		1.14293
	804		Rooted	74.3877	79.1931		1.0646
	880	Low confidence	Measured	8256.68	8587.03		1.04001
	1032	High confidence	Ranked	186.664	180.943		1.03162
	1084	Low confidence	Rooted	73.5068	76.3467		1.03863
	1322		Ranked	198.322	194.014		1.0222
	4569		Squared	46616.1	45740.5		1.01914
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	237		Measured	8530.51	9081.29		1.06457
	311	High confidence	Squared	30566.4	38866.5		1.27154
	378	Low confidence	Rooted	75.8843	79.5804		1.04871
	514	High confidence	Measured	7477	8532.02		1.1411
	588	Low confidence	Ranked	191.507	185.859		1.03039
	822	High confidence	Rooted	73.8577	78.5795		1.06393
	1048		Ranked	187.96	182.308		1.031
	4138	Low confidence	Squared	46138.2	47372.8		1.02676
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	252		Measured	8492.92	9018.94		1.06194
	308	High confidence	Squared	30596.2	38919.9		1.27205
	427	Low confidence	Rooted	75.6219	79.1997		1.04731
	513	High confidence	Measured	7485.08	8543.66		1.14143
	637	Low confidence	Ranked	192.166	186.751		1.029
	811	High confidence	Rooted	73.9102	78.6514		1.06415
	1043		Ranked	187.834	182.137		1.03128
	4418	Low confidence	Squared	46049.4	47088.3		1.02256
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	2035		Measured	8065.05	8323.04		1.03199
	2766		Rooted	72.5914	74.9741		1.03282

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.