MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

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Showing element 201 to 250 of 9634 in total

Value Type  : Measured
Network Comparison Type  : Divided

description	Rank	Interaction Map	Filtered	red	green	network_comparison
40s ribosomal protein s28. [swissprot;acc:p25112]	385	High confidence	0	387.486	405.367	1.04615
	550	Low confidence		890.008	936.963	1.05276
	700	High confidence	1	7161.14	8015.92	1.11936
	3584	Low confidence		8199.31	8409.22	1.0256
40s ribosomal protein s29. [swissprot;acc:p30054]	297	High confidence	0	1711.6	1895.38	1.10737
	356	Low confidence		1965.77	2217.3	1.12795
	1756	High confidence	1	3582.57	3357.6	1.067
	4862	Low confidence		7407.06	7472.73	1.00887
40s ribosomal protein s3. [swissprot;acc:p23396]	2235	High confidence		3674.29	3508.13	1.04736
	4486	Low confidence		7494.6	7635.68	1.01882
40s ribosomal protein s30. [swissprot;acc:q05472]	1145	High confidence		5893.97	6416.07	1.08858
	2921	Low confidence		7903.47	8127.82	1.02839
40s ribosomal protein s3a. [swissprot;acc:p49241]	439		0	1910.16	2069.56	1.08345
	447	High confidence		2929.51	2879.55	1.01735
	2263		1	4918.64	5145.39	1.0461
	3677	Low confidence		7857.88	8053.5	1.02489
40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750]	255	High confidence	0	1317.84	1495.22	1.1346
	416	Low confidence		1512.43	1653.68	1.09339
	1974	High confidence	1	3678.62	3470.64	1.05993
	4806	Low confidence		7229.75	7306.45	1.01061
40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47]	254	High confidence	0	1318.22	1495.66	1.13461
	415	Low confidence		1509.52	1651.01	1.09373
	1967	High confidence	1	3678.56	3470.55	1.05994
	4808	Low confidence		7228.89	7305.35	1.01058
40s ribosomal protein s5. [swissprot;acc:p46782]	2343	High confidence		3672.17	3516.98	1.04413
	4222	Low confidence		7495.04	7645.87	1.02012
40s ribosomal protein s7 (s8). [swissprot;acc:p23821]	1642	High confidence		5782.92	6186.39	1.06977
	2244	Low confidence		7780.28	8023.9	1.03131
40s ribosomal protein s8. [swissprot;acc:p09058]	1471	High confidence		5659.45	6087.55	1.07564
	4923	Low confidence		8525.9	8569.5	1.00511
40s ribosomal protein s9. [swissprot;acc:p46781]	2628	High confidence		3933.74	3877.14	1.0146
	3586	Low confidence		7711.01	7908.36	1.02559
40s ribosomal protein sa (p40) (34/67 kda laminin receptor) (colon carcinoma laminin-binding protein) (nem/1chd4) (multidrug resistance- associated protein mgr1-ag). [swissprot;acc:p08865]	315	High confidence	0	1212.82	1104.61	1.09796
	743	Low confidence		827.585	838.364	1.01302
	2402	High confidence	1	5078.5	5275.76	1.03884
	3484	Low confidence		7919.03	8125.51	1.02607
43 kda receptor-associated protein of the synapse (rapsyn) (acetylcholine receptor-associated 43 kda protein) (43 kda postsynaptic protein). [swissprot;acc:q13702]	1402	High confidence		6160.06	6640.78	1.07804
	3491	Low confidence		8052.19	8261.9	1.02604
44050 protein. [refseq;acc:nm_178832]	376	High confidence		17385.9	14889.2	1.16769
	4703	Low confidence		8386.63	8507.06	1.01436
45 kda calcium-binding protein precursor (cab45) (stromal cell-derived factor 4) (sdf-4). [swissprot;acc:q9brk5]	587			7995.61	8360.72	1.04566
	972	High confidence		7813.48	8570.11	1.09684
5'-amp-activated protein kinase, beta-1 subunit (ampk beta-1 chain) (ampkb). [swissprot;acc:q9y478]	691			6920.69	7747.63	1.11949
	3556	Low confidence		8139.14	8348.29	1.0257
5'-amp-activated protein kinase, beta-2 subunit (ampk beta-2 chain). [swissprot;acc:o43741]	689	High confidence		6920.69	7747.63	1.11949
	3509	Low confidence		8136.52	8347.85	1.02597
5'-amp-activated protein kinase, catalytic alpha-1 chain (ec 2.7.1.-) (ampk alpha-1 chain). [swissprot;acc:q13131]	688	High confidence		6920.67	7747.6	1.11949
	3045	Low confidence		8168.9	8396.61	1.02788
5'-amp-activated protein kinase, catalytic alpha-2 chain (ec 2.7.1.-) (ampk alpha-2 chain). [swissprot;acc:p54646]	687	High confidence		6920.71	7747.65	1.11949
	3059	Low confidence		8169.23	8396.61	1.02783

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.