MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Filtered	Gene	Rank	Value Type	Network Comparison Type	green	Interaction Map	red	network_comparison

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Showing element 51 to 100 of 77072 in total

Filtered  : 1

description	Rank	Value Type	Network Comparison Type	green	Interaction Map	red	network_comparison
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	307	Measured	Subtracted	8636.87	High confidence	7556.75	1080.12
	508		Divided				1.14293
	609	Rooted	Subtracted	79.1931		74.3877	4.8054
	773	Measured		8587.03	Low confidence	8256.68	330.35
	804	Rooted	Divided	79.1931	High confidence	74.3877	1.0646
	880	Measured		8587.03	Low confidence	8256.68	1.04001
	977	Rooted	Subtracted	76.3467		73.5068	2.8399
	1032	Ranked	Divided	180.943	High confidence	186.664	1.03162
	1084	Rooted		76.3467	Low confidence	73.5068	1.03863
	1115	Ranked	Subtracted	180.943	High confidence	186.664	5.721
	1322		Divided	194.014	Low confidence	198.322	1.0222
	1406		Subtracted				4.308
	4523	Squared		45740.5		46616.1	875.6
	4569		Divided				1.01914
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	210	Measured	Subtracted	9081.29		8530.51	550.78
	237		Divided				1.06457
	280	Squared	Subtracted	38866.5	High confidence	30566.4	8300.1
	311		Divided				1.27154
	319	Measured	Subtracted	8532.02		7477	1055.02
	331	Rooted		79.5804	Low confidence	75.8843	3.6961
	378		Divided				1.04871
	514	Measured		8532.02	High confidence	7477	1.1411
	588	Ranked		185.859	Low confidence	191.507	1.03039
	631	Rooted	Subtracted	78.5795	High confidence	73.8577	4.7218
	664	Ranked		185.859	Low confidence	191.507	5.648
	822	Rooted	Divided	78.5795	High confidence	73.8577	1.06393
	1048	Ranked		182.308		187.96	1.031
	1128		Subtracted				5.652
	3936	Squared		47372.8	Low confidence	46138.2	1234.6
	4138		Divided				1.02676
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	230	Measured	Subtracted	9018.94		8492.92	526.02
	252		Divided				1.06194
	279	Squared	Subtracted	38919.9	High confidence	30596.2	8323.7
	308		Divided				1.27205
	318	Measured	Subtracted	8543.66		7485.08	1058.58
	369	Rooted		79.1997	Low confidence	75.6219	3.5778
	427		Divided				1.04731
	513	Measured		8543.66	High confidence	7485.08	1.14143
	616	Rooted	Subtracted	78.6514		73.9102	4.7412
	637	Ranked	Divided	186.751	Low confidence	192.166	1.029
	737		Subtracted				5.415
	811	Rooted	Divided	78.6514	High confidence	73.9102	1.06415
	1043	Ranked		182.137		187.834	1.03128
	1121		Subtracted				5.697
	4331	Squared		47088.3	Low confidence	46049.4	1038.9
	4418		Divided				1.02256
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	1941	Measured	Subtracted	8323.04		8065.05	257.99
	2035		Divided				1.03199
	2688	Rooted	Subtracted	74.9741		72.5914	2.3827
	2766		Divided				1.03282

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.