MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Network Comparison Type	Gene	Value Type	Hugo	Interaction Map	red	Filtered	green	network_comparison

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Showing element 2512 to 2561 of 66312 in total

Filtered  : 1

description	Rank	Network Comparison Type	Value Type	Hugo	Interaction Map	red	green	network_comparison
60s ribosomal protein l32. [swissprot;acc:p02433]	2338	Subtracted	Measured	SNORA7A	High confidence	3618.02	3394.29	223.73
	2523		Squared			12314	13403.2	1089.2
	2575				Low confidence	41067.2	39442.3	1624.9
	2900		Ranked			207.568	210.937	3.369
	3156	Divided						1.01623
	4750		Measured			7365.11	7460.59	1.01296
	4779	Subtracted						95.48
	4911	Divided	Rooted			68.7786	69.4465	1.00971
	4921	Subtracted						0.6679
60s ribosomal protein l34, mitochondrial precursor (l34mt). [swissprot;acc:q9bq48]	1174	Divided		MRPL34	High confidence	60.9172	63.8009	1.04734
	1192	Subtracted						2.8837
	1296		Ranked			220.681	215.78	4.901
	1300	Divided	Measured			5589.33	6047.9	1.08204
	1333		Ranked			220.681	215.78	1.02271
	1366	Subtracted	Measured			5589.33	6047.9	458.57
	1993		Squared			24896.2	26952.9	2056.7
	2238	Divided						1.08261
	2366		Measured		Low confidence	7787.79	8027.95	1.03084
	2473	Subtracted						240.16
	3117	Divided	Squared			44268.2	42776.8	1.03486
	3161	Subtracted						1491.4
	3175	Divided	Rooted			70.7822	73.0131	1.03152
	3300	Subtracted						2.2309
	3823		Ranked			204.301	201.678	2.623
	3852	Divided						1.01301
60s ribosomal protein l34. [swissprot;acc:p49207]	224	Subtracted		RPL34	High confidence	242.153	266.673	24.52
	308	Divided						1.10126
	389		Rooted			50.3345	45.6718	1.10209
	660	Subtracted						4.6627
	2005	Divided	Squared			12429.9	13562.6	1.09113
	2077		Measured			3614.91	3423.89	1.05579
	2394	Subtracted						191.02
	2506		Squared			12429.9	13562.6	1132.7
	3929	Divided	Measured		Low confidence	7780.25	7959.81	1.02308
	3940	Subtracted	Squared			44208.8	42975.3	1233.5
	3956	Divided						1.0287
	4134	Subtracted	Measured			7780.25	7959.81	179.56
	4606	Divided	Rooted			70.7448	72.1958	1.02051
	4639	Subtracted						1.451
	4901		Ranked			204.23	204.633	0.403
	4903	Divided						1.00197
60s ribosomal protein l35. [swissprot;acc:p42766]	218	Subtracted		RPL35	High confidence	242.333	266.999	24.666
	303	Divided						1.10179
	375		Rooted			50.2545	45.5637	1.10295
	640	Subtracted						4.6908
	1992	Divided	Squared			12384	13518	1.09157
	2065		Measured			3602.25	3410.23	1.05631
	2389	Subtracted						192.02
	2499		Squared			12384	13518	1134
	2527	Divided			Low confidence	42005.9	40454.5	1.03835

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.