MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Network Comparison Type	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

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Showing element 2501 to 2550 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	Interaction Map	red	green	network_comparison
carboxypeptidase n 83 kda chain (carboxypeptidase n regulatory subunit) (fragment). [swissprot;acc:p22792]	4834	Divided	CPN2	Low confidence	184.376	183.711	1.00362
	4841	Subtracted					0.665
carboxypeptidase n catalytic chain precursor (ec 3.4.17.3) (arginine carboxypeptidase) (kininase 1) (serum carboxypeptidase n) (scpn) (anaphylatoxin inactivator) (plasma carboxypeptidase b). [swissprot;acc:p15169]	689		CPN1	High confidence	223.121	211.685	11.436
	715	Divided					1.05402
	3409	Subtracted		Low confidence	201.289	198.276	3.013
	3432	Divided					1.0152
carcinoma related gene. [refseq;acc:nm_016041]	3179		DERL2	High confidence	0.00001	0.00001	1
		Subtracted			0	0	0
	5058	Divided		Low confidence	0.00001	0.00001	1
		Subtracted			0	0	0
carnitine o-acetyltransferase (ec 2.3.1.7) (carnitine acetylase) (cat). [swissprot;acc:p43155]	1692		CRAT	High confidence	217.624	214.69	2.934
	1698	Divided					1.01367
	4302	Subtracted		Low confidence	202.986	201.152	1.834
	4463	Divided					1.00912
carnitine o-palmitoyltransferase i, mitochondrial liver isoform (ec 2.3.1.21) (cpt i) (cpti-l). [swissprot;acc:p50416]	1058	Subtracted	CPT1A		203.519	198.789	4.73
	1099	Divided					1.02379
carnitine o-palmitoyltransferase i, mitochondrial muscle isoform (ec 2.3.1.21) (cpt i) (cpti-m) (carnitine palmitoyltransferase i like protein). [swissprot;acc:q92523]	1631		CHKB		199.793	195.725	1.02078
	1644	Subtracted					4.068
carnitine o-palmitoyltransferase ii, mitochondrial precursor (ec 2.3.1.21) (cpt ii). [swissprot;acc:p23786]	2885	Divided	CPT2	High confidence	0.00001	0.00001	1
		Subtracted			0	0	0
	3335	Divided		Low confidence	196.512	193.497	1.01558
	3406	Subtracted					3.015
carnitine palmitoyltransferase i related c. [refseq;acc:nm_152359]	1057		CPT1C		203.519	198.789	4.73
	1091	Divided					1.02379
cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]	141	Subtracted	COMP	High confidence	239.991	269.238	29.247
	226	Divided					1.12187
	4692	Subtracted		Low confidence	213.766	214.907	1.141
	4745	Divided					1.00534
casein kinase i alpha s-like. [refseq;acc:nm_145203]	1427	Subtracted	CSNK1A1L	High confidence	229.459	225.237	4.222
	1495	Divided					1.01874
	3590			Low confidence	199.578	196.734	1.01446
	3616	Subtracted					2.844
casein kinase i, alpha isoform (ec 2.7.1.-) (cki-alpha) (ck1). [swissprot;acc:p48729]	1428		CSNK1A1	High confidence	229.459	225.237	4.222
	1496	Divided					1.01874
	3591			Low confidence	199.578	196.734	1.01446
	3617	Subtracted					2.844
casein kinase i, delta isoform (ec 2.7.1.-) (cki-delta) (ckid). [swissprot;acc:p48730]	1679		CSNK1D	High confidence	227.125	224.164	2.961
	1721	Divided					1.01321
	3521			Low confidence	199.471	196.561	1.0148
	3551	Subtracted					2.91
casein kinase i, epsilon isoform (ec 2.7.1.-) (cki-epsilon) (ckie). [swissprot;acc:p49674]	1663		no value	High confidence	227.225	224.21	3.015
	1710	Divided					1.01345
	3527			Low confidence	199.463	196.557	1.01478
	3553	Subtracted					2.906
casein kinase i, gamma 1 isoform (ec 2.7.1.-) (cki-gamma 1). [swissprot;acc:q9hcp0]	2830	Divided	CSNK1G1	High confidence	0.00001	0.00001	1
		Subtracted			0	0	0
	4010	Divided		Low confidence	196.478	194.223	1.01161
	4049	Subtracted					2.255
casein kinase i, gamma 2 isoform (ec 2.7.1.-) (cki-gamma 2). [swissprot;acc:p78368]	2986	Divided	CSNK1G2	High confidence	0.00001	0.00001	1
		Subtracted			0	0	0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.