MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2475 to 2524 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
arginine/serine-rich splicing factor 10 (transformer-2-beta) (htra2- beta) (transformer 2 protein homolog) (silica-induced protein 41) (ra301). [swissprot;acc:q15815]	993	SFRS10	Measured	Divided	6499.89	7121.77	1.09568
	1045		Squared		31783.9	36463.3	1.14723
	1089		Rooted	Subtracted	64.9094	68.0692	3.1598
	1134			Divided			1.04868
	1460		Ranked	Subtracted	215.122	211.066	4.056
	1478			Divided			1.01922
argininosuccinate lyase (ec 4.3.2.1) (arginosuccinase) (asal). [swissprot;acc:p04424]	511	ASL	Squared	Subtracted	26048.6	31057.4	5008.8
	540			Divided			1.19229
	1068		Measured	Subtracted	5857.48	6380.4	522.92
	1123			Divided			1.08927
	2040		Rooted	Subtracted	62.6557	64.3308	1.6751
	2046			Divided			1.02673
	2096		Ranked	Subtracted	216.36	217.93	1.57
	2108			Divided			1.00726
argininosuccinate synthase (ec 6.3.4.5) (citrulline--aspartate ligase). [swissprot;acc:p00966]	929	ASS1	Squared	Subtracted	24976.9	28625.4	3648.5
	1084			Divided			1.14607
	1540		Ranked	Subtracted	217.769	221.474	3.705
	1546			Divided			1.01701
	1739		Measured		5695.57	6079.61	1.06743
	1802			Subtracted			384.04
	2428		Rooted		61.8651	62.7331	0.868
	2444			Divided			1.01403
arginyl-trna synthetase-like; arginine-trna ligase. [refseq;acc:nm_020320]	315	RARS2	Squared	Subtracted	31819.7	39222.2	7402.5
	389			Divided			1.23264
	592		Measured	Subtracted	7093.86	7842.67	748.81
	839			Divided			1.10556
	1264		Rooted	Subtracted	69.8799	72.6645	2.7846
	1396			Divided			1.03985
	2235		Ranked		200.95	199.711	1.0062
	2252			Subtracted			1.239
ariadne-2 protein homolog (ari-2) (triad1 protein) (ht005). [swissprot;acc:o95376]	2798	ARIH2	Measured	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Ranked	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Squared	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Rooted	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
armet protein precursor (arginine-rich protein). [swissprot;acc:p55145]	269	ARMET	Squared		35508.7	44191.4	8682.7
	350			Divided			1.24452
	489		Measured	Subtracted	7101.95	7949.85	847.9
	698			Divided			1.11939
	1006		Rooted	Subtracted	68.4309	71.8158	3.3849
	1111			Divided			1.04946
	1714		Ranked		206.549	203.844	1.01327
	1753			Subtracted			2.705
arp2/3 complex 16 kda subunit (p16-arc) (actin-related protein 2/3 complex subunit 5). [swissprot;acc:o15511]	1788	ARPC5	Measured	Divided	5386.49	5744.76	1.06651
	1886		Squared	Subtracted	24224.5	26398.4	2173.9
	1926		Measured		5386.49	5744.76	358.27
	2025		Rooted	Divided	59.3853	61.0095	1.02735

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.