MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2462 to 2511 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	green	network_comparison
carbohydrate (keratan sulfate gal-6) sulfotransferase 1; carbohydrate (chondroitin 6/keratan) sulfotransferase 1. [refseq;acc:nm_003654]	4546	CHST1	Divided	Low confidence	202.436	200.827	1.00801
carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 4; n-acetylglucosamine 6-o-sulfotransferase. [refseq;acc:nm_005769]	4547	CHST4	Subtracted				1.609
	4552		Divided				1.00801
carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 5; n-acetylglucosamine 6-o-sulfotransferase. [refseq;acc:nm_012126]	4549	CHST5	Subtracted				1.609
	4554		Divided				1.00801
carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [refseq;acc:nm_021615]	4540	CHST6	Subtracted				1.609
	4545		Divided				1.00801
carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 7; chondroitin 6-sulfotransferase-2. [refseq;acc:nm_019886]	4546	CHST7	Subtracted				1.609
	4551		Divided				1.00801
carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [refseq;acc:nm_004267]	4542	CHST2	Subtracted				1.609
	4547		Divided				1.00801
carbonic anhydrase-related protein 10 (carbonic anhydrase-related protein x) (carp x) (ca-rp x) (cerebral protein-15) (hucep-15). [swissprot;acc:q9ns85]	2190	CA10	Subtracted		205.17	201.427	3.743
	2360		Divided				1.01858
carbonic anhydrase-related protein 2 precursor (carp-2) (ca-rp ii) (ca-xi) (carbonic anhydrase-related protein 11) (carp xi) (ca-rp xi). [swissprot;acc:o75493]	2197	CA11	Subtracted		205.147	201.407	3.74
	2368		Divided				1.01857
carboxypeptidase a1 precursor (ec 3.4.17.1). [swissprot;acc:p15085]	1329	CPA1			187.586	183.516	1.02218
	1422			High confidence	203.979	208.229	1.02084
	1425		Subtracted				4.25
	1638			Low confidence	187.586	183.516	4.07
carboxypeptidase a4 precursor (ec 3.4.17.-) (carboxypeptidase a3). [swissprot;acc:q9ui42]	2760	CPA4	Divided		195.28	191.932	1.01744
	2940		Subtracted				3.348
carboxypeptidase a5. [refseq;acc:nm_080385]	1349	CPA5	Divided		187.671	183.613	1.0221
	1417			High confidence	203.979	208.229	1.02084
	1421		Subtracted				4.25
	1667			Low confidence	187.671	183.613	4.058
carboxypeptidase b precursor (ec 3.4.17.2) (pancreas-specific protein) (pasp). [swissprot;acc:p15086]	1352	CPB1	Divided		187.651	183.595	1.02209
	1418			High confidence	203.979	208.229	1.02084
	1422		Subtracted				4.25
	1672			Low confidence	187.651	183.595	4.056
carboxypeptidase b precursor. [refseq;acc:nm_020361]	509	CPA6	Divided	High confidence	177.698	190.239	1.07057
	617		Subtracted				12.541
	3976		Divided	Low confidence	192.47	190.192	1.01198
	4035		Subtracted				2.278
carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	1	CPD	Divided		16	32	2
	88		Subtracted				16
carboxypeptidase h precursor (ec 3.4.17.10) (cph) (carboxypeptidase e) (cpe) (enkephalin convertase) (prohormone processing carboxypeptidase). [swissprot;acc:p16870]	691	CPE		High confidence	223.121	211.685	11.436
	717		Divided				1.05402
	3371		Subtracted	Low confidence	201.399	198.351	3.048
	3381		Divided				1.01537
carboxypeptidase n 83 kda chain (carboxypeptidase n regulatory subunit) (fragment). [swissprot;acc:p22792]	4834	CPN2			184.376	183.711	1.00362
	4841		Subtracted				0.665
carboxypeptidase n catalytic chain precursor (ec 3.4.17.3) (arginine carboxypeptidase) (kininase 1) (serum carboxypeptidase n) (scpn) (anaphylatoxin inactivator) (plasma carboxypeptidase b). [swissprot;acc:p15169]	689	CPN1		High confidence	223.121	211.685	11.436
	715		Divided				1.05402
	3409		Subtracted	Low confidence	201.289	198.276	3.013
	3432		Divided				1.0152
carcinoma related gene. [refseq;acc:nm_016041]	3179	DERL2		High confidence	0.00001	0.00001	1
			Subtracted		0	0	0
	5058		Divided	Low confidence	0.00001	0.00001	1
			Subtracted		0	0	0
carnitine o-acetyltransferase (ec 2.3.1.7) (carnitine acetylase) (cat). [swissprot;acc:p43155]	1692	CRAT		High confidence	217.624	214.69	2.934

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.