MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2451 to 2500 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Hugo	red	green	network_comparison
2451	secretory carrier-associated membrane protein 2. [swissprot;acc:o15127]	SCAMP2	204.688	205.333	1.00315
2452	secretory carrier-associated membrane protein 3. [swissprot;acc:o14828]	SCAMP3
2453	secretory carrier-associated membrane protein 1. [swissprot;acc:o15126]	SCAMP1		205.332
2454	solute carrier family 13, member 4 (na+/sulfate cotransporter sut-1). [swissprot;acc:q9ukg4]	SLC13A4	204.683	205.326	1.00314
2455	solute carrier family 13, member 3 (sodium-dependent high-affinity dicarboxylate transporter 2) (na(+)/dicarboxylate cotransporter 3) (nadc-3) (hnadc3). [swissprot;acc:q8wwt9]	SLC13A3
2456	solute carrier family 13, member 1 (renal sodium/sulfate cotransporter) (na(+)/sulfate cotransporter) (hnasi-1). [swissprot;acc:q9bzw2]	SLC13A1
2457	vesicle-fusing atpase (ec 3.6.4.6) (vesicular-fusion protein nsf) (n- ethylmaleimide sensitive fusion protein) (nem-sensitive fusion protein). [swissprot;acc:p46459]	NSF	213.588	212.92
2458	solute carrier family 13, member 2 (renal sodium/dicarboxylate cotransporter) (na(+)/dicarboxylate cotransporter 1) (nadc-1). [swissprot;acc:q13183]	SLC13A2	204.683	205.326
2459	phosphatidate cytidylyltransferase 1 (ec 2.7.7.41) (cdp-diglyceride synthetase 1) (cdp-diglyceride pyrophosphorylase 1) (cdp- diacylglycerol synthase 1) (cds 1) (ctp:phosphatidate cytidylyltransferase 1) (cdp-dag synthase 1) (cdp-dg synthetase 1). [swissprot;acc:q92903]	CDS1	204.653	205.286	1.00309
2460	pepsin a precursor (ec 3.4.23.1). [swissprot;acc:p00790]	no value	235.812	235.088	1.00308
2461	solute carrier family 20 (phosphate transporter), member 2; glvr-2; pit-2; gibbon ape leukemia virus receptor 2; murine leukemia virus, amphotropic; receptor. [refseq;acc:nm_006749]	SLC20A2
2462	farnesyl pyrophosphate synthetase (fpp synthetase) (fps) (farnesyl diphosphate synthetase) [includes: dimethylallyltransferase (ec 2.5.1.1); geranyltranstransferase (ec 2.5.1.10)]. [swissprot;acc:p14324]	FDPS
2463	protocadherin 15 precursor. [swissprot;acc:q96qu1]	PCDH15
2464	solute carrier family 20 (phosphate transporter), member 1; glvr-1; pit-1; gibbon ape leukemia virus receptor 1. [refseq;acc:nm_005415]	SLC20A1
2465	lipocalin-interacting membrane receptor. [refseq;acc:nm_018113]	LMBR1L
2466	zinc finger protein gli1 (glioma-associated oncogene) (oncogene gli). [swissprot;acc:p08151]	GLI1
2467	suppressor of fused. [refseq;acc:nm_016169]	SUFU
2468	zinc finger protein gli3. [swissprot;acc:p10071]	GLI3
2469	limb region 1 protein; limb region 1. [refseq;acc:nm_022458]	LMBR1
2470	gastricsin precursor (ec 3.4.23.3) (pepsinogen c). [swissprot;acc:p20142]	PGC
2471	zinc finger protein gli2 (tax helper protein). [swissprot;acc:p10070]	GLI2
2472	tumor endothelial marker 6; thyroid specific ptb domain protein; tensin 3. [refseq;acc:nm_022748]	TNS3	218.218	217.564	1.00301
2473	c-jun-amino-terminal kinase interacting protein 3 (jnk-interacting protein 3) (jip-3) (jnk map kinase scaffold protein 3) (mitogen- activated protein kinase 8-interacting protein 3). [swissprot;acc:q9upt6]	MAPK8IP3	218.644	217.991	1.003
2474	26s protease regulatory subunit 6a (tat-binding protein 1) (tbp-1) (proteasome subunit p50). [swissprot;acc:p17980]	PSMC3	216.64	217.285	1.00298
2475	c1 domain-containing phosphatase and tensin-like protein isoform 2; putative protein tyrosine phosphatase; c1 domain-containing phosphatase and tensin-like protein; tensin 2. [refseq;acc:nm_015319]	TENC1	218.219	217.571
2476	xylulokinase homolog; xylulokinase (h. influenzae) homolog. [refseq;acc:nm_005108]	XYLB	211.205	210.577
2477	mitochondrial ribosomal protein l30 isoform a. [refseq;acc:nm_145212]	MRPL30	216.177	216.801	1.00289
2478	26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	PSMC6
2479	rho-gtpase-activating protein 8. [swissprot;acc:q9nsg0]	PRR5	218.093	218.72	1.00287
2480	rho-gtpase-activating protein 1 (gtpase-activating protein rhoogap) (rho-related small gtpase protein activator) (cdc42 gtpase-activating protein) (p50-rhogap). [swissprot;acc:q07960]	ARHGAP1
2481	kinesin light chain 2 (klc 2). [swissprot;acc:q9h0b6]	KLC2
2482	kinesin heavy chain (ubiquitous kinesin heavy chain) (ukhc). [swissprot;acc:p33176]	KIF5B
2483	kinesin heavy chain isoform 5c (kinesin heavy chain neuron-specific 2). [swissprot;acc:o60282]	KIF5C
2484	neuronal kinesin heavy chain (nkhc) (kinesin heavy chain isoform 5a) (kinesin heavy chain neuron-specific 1). [swissprot;acc:q12840]	KIF5A
2485	kinesin light chain 1 (klc 1). [swissprot;acc:q07866]	KLC1
2486	transcription factor iiia (factor a) (tfiiia). [swissprot;acc:q92664]	GTF3A
2487	exocyst complex component sec3 (bm-012). [swissprot;acc:q9nv70]	EXOC1
2488	hepatitis c virus core-binding protein 6; cervical cancer oncogene 3. [refseq;acc:nm_023934]	no value	194.527	195.08	1.00284
2489	dc11 protein. [refseq;acc:nm_020186]
2490	amyloid beta precursor protein-binding protein 1; amyloid protein-binding protein 1. [refseq;acc:nm_003905]	APPBP1
2491	5-aminolevulinic acid synthase, erythroid-specific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-e). [swissprot;acc:p22557]	ALAS2
2492	ubiquitin-activating enzyme e1c (uba3 homolog, yeast); ubiquitin-activating enzyme e1c (homologous to yeast uba3). [refseq;acc:nm_003968]	UBE1C
2493	ubiquitin-activating enzyme e1 (a1s9 protein). [swissprot;acc:p22314]	UBE1
2494	calcium-binding mitochondrial carrier protein aralar1 (solute carrier family 25, member 12). [swissprot;acc:o75746]	SLC25A12
2495	melanoma antigen recognized by t cells 2. [refseq;acc:nm_018194]	HHAT
2496	5-aminolevulinic acid synthase, nonspecific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-h). [swissprot;acc:p13196]	ALAS1
2497	calcium-binding mitochondrial carrier protein aralar2 (solute carrier family 25, member 13) (citrin). [swissprot;acc:q9ujs0]	SLC25A13
2498	acyl carrier protein, mitochondrial precursor (acp) (nadh-ubiquinone oxidoreductase 9.6 kda subunit) (ci-sdap). [swissprot;acc:o14561]	NDUFAB1
2499	nin one binding protein; adenocarcinoma antigen recognized by t lymphocytes 4. [refseq;acc:nm_014062]	NOB1	231.414	230.76	1.00283
2500	baculoviral iap repeat-containing protein 5 (apoptosis inhibitor survivin) (apoptosis inhibitor 4). [swissprot;acc:o15392]	BIRC5	218.949	219.552	1.00275

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.