MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Network Comparison Type	Gene	Value Type	Hugo	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 2308 to 2357 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	red	network_comparison	green
glycine receptor alpha-3 chain precursor. [swissprot;acc:o75311]	2920	Subtracted	GLRA3	0	0	0
glycine receptor beta chain precursor (glycine receptor 58 kda subunit). [swissprot;acc:p48167]	3083	Divided	GLRB	0.00001	1	0.00001
		Subtracted		0	0	0
glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216]	19	Divided	PYGB	185.678	1.32082	245.247
	55	Subtracted			59.569
glycogen phosphorylase, liver form (ec 2.4.1.1). [swissprot;acc:p06737]	20	Divided	PYGL		1.32082
	56	Subtracted			59.569
glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [swissprot;acc:p11217]	22	Divided	PYGM		1.32082
	58	Subtracted			59.569
glycogen synthase kinase-3 alpha (ec 2.7.1.37) (gsk-3 alpha). [swissprot;acc:p49840]	2186	Divided	GSK3A	211.713	1.00663	210.318
	2190	Subtracted			1.395
glycogen synthase kinase-3 beta (ec 2.7.1.37) (gsk-3 beta). [swissprot;acc:p49841]	2187	Divided	GSK3B		1.00663
	2191	Subtracted			1.395
glycogen [starch] synthase, liver (ec 2.4.1.11). [swissprot;acc:p54840]	1324	Divided	GYS2	159.993	1.02284	156.421
	1574	Subtracted			3.572
glycogen [starch] synthase, muscle (ec 2.4.1.11). [swissprot;acc:p13807]	1319	Divided	GYS1	159.75	1.02304	156.153
	1569	Subtracted			3.597
glycogenin-1 (ec 2.4.1.186). [swissprot;acc:p46976]	2562	Divided	GYG1	208.429	1.00168	208.779
	2563	Subtracted			0.35
glycogenin-2 (ec 2.4.1.186) (gn-2) (gn2). [swissprot;acc:o15488]	2565	Divided	GYG2		1.00168
	2566	Subtracted			0.35
glycyl-trna synthetase (ec 6.1.1.14) (glycine--trna ligase) (glyrs). [swissprot;acc:p41250]	1431		GARS	221.412	4.213	217.199
	1472	Divided			1.0194
gmp synthase [glutamine-hydrolyzing] (ec 6.3.5.2) (glutamine amidotransferase) (gmp synthetase). [swissprot;acc:p49915]	1676	Subtracted	GMPS	218.937	2.966	215.971
	1694	Divided			1.01373
golgi complex associated protein 1; golgi resident protein gcp60; peripherial benzodiazepine receptor associated protein; golgi phosphoprotein 1; pbr associated protein; pka (rialpha)-associated protein. [refseq;acc:nm_022735]	1152	Subtracted	ACBD3	218.186	5.514	212.672
	1177	Divided			1.02593
golgi membrane protein sb140; smooth muscle cell associated protein 5. [refseq;acc:nm_030799]	1930	Subtracted	YIPF5	211.633	2.07	213.703
	1960	Divided			1.00978
golgi reassembly stacking protein 2; golgi reassembly stacking protein 2, 55 kda. [refseq;acc:nm_015530]	1835		GORASP2	194.573	1.01132	192.396
	1905	Subtracted			2.177
goodpasture antigen-binding protein (ec 2.7.1.37) (gpbp) (collagen type iv alpha 3 binding protein) (star-related lipid transfer protein 11) (stard11) (start domain-containing protein 11). [swissprot;acc:q9y5p4]	1994	Divided	COL4A3BP	189.011	1.0094	190.787
	2049	Subtracted			1.776
gpi transamidase component pig-s (phosphatidylinositol-glycan biosynthesis, class s protein). [swissprot;acc:q96s52]	3165	Divided	PIGS	0.00001	1	0.00001
		Subtracted		0	0	0
grancalcin. [swissprot;acc:p28676]	942	Divided	GCA	212.442	1.03586	205.088
		Subtracted			7.354
grb2-related adaptor protein 2 (gads protein) (growth factor receptor binding protein) (grblg) (grf40 adaptor protein) (grf-40) (grb-2-like protein) (grb2l) (grbx) (p38) (hematopoietic cell-associated adaptor protein grpl) (adapter protein grid) (sh3-sh2-sh3 adaptor mona). [swissprot;acc:o75791]	551	Divided	GRAP2	207.261	1.06645	194.347
	598	Subtracted			12.914
grb2-related adaptor protein. [swissprot;acc:q13588]	441	Divided	GRAP	223.457	1.07835	207.222
	454	Subtracted			16.235
growth arrest and dna-damage-inducible protein gadd45 alpha (dna- damage inducible transcript 1) (ddit1). [swissprot;acc:p24522]	995		GADD45A	251.863	6.966	258.829
	1114	Divided			1.02766
growth arrest and dna-damage-inducible protein gadd45 beta (negative growth-regulatory protein myd118) (myeloid differentiation primary response protein myd118). [swissprot;acc:o75293]	997	Subtracted	GADD45B		6.966
	1116	Divided			1.02766
growth arrest and dna-damage-inducible protein gadd45 gamma (cytokine responsive protein cr6). [swissprot;acc:o95257]	994	Subtracted	GADD45G		6.966
	1113	Divided			1.02766
growth factor receptor-bound protein 2 (grb2 adapter protein) (sh2/sh3 adapter grb2) (ash protein). [swissprot;acc:p29354]	446		GRB2	224.049	1.07827	207.785
		Subtracted			16.264
growth-arrest-specific protein 7 (gas-7). [swissprot;acc:o60861]	1348		GAS7	218.47	4.594	213.876

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.