MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2308 to 2357 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
apg3p; pc3-96 protein. [refseq;acc:nm_022488]	71	ATG3	Squared	Subtracted	129597	73157.5	56439.5
	135		Measured	Divided	21785.2	16426.1	1.32626
	169		Ranked		82.5916	98.0548	1.18722
	207		Rooted		140.508	122.878	1.14348
	489		Ranked	Subtracted	82.5916	98.0548	15.4632
apical-like protein (apxl protein). [swissprot;acc:q13796]	331	SHROOM2	Rooted	Divided	60.6697	67.2802	1.10896
	346		Ranked	Subtracted	231.492	211.136	20.356
	362			Divided			1.09641
	366		Rooted	Subtracted	60.6697	67.2802	6.6105
	595		Measured		6088.77	6834.87	746.1
	658			Divided			1.12254
	1290		Squared	Subtracted	30517.3	33442.4	2925.1
	1849			Divided			1.09585
apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576]	160	no value	Rooted		52.7642	61.9019	1.17318
	183		Measured		4069.83	5252.17	1.29051
	211		Ranked	Subtracted	237.302	212.41	24.892
	248			Divided			1.11719
	263		Rooted	Subtracted	52.7642	61.9019	9.1377
	287		Measured		4069.83	5252.17	1182.34
	383		Squared	Divided	15043.7	18560.1	1.23375
	983			Subtracted			3516.4
apolipoprotein a-i binding protein; apoa-i binding protein. [refseq;acc:nm_144772]	419	APOA1BP		Divided	24832.1	30242.8	1.21789
	468			Subtracted			5410.7
	586		Measured		6139.04	6893.7	754.66
	656			Divided			1.12293
	1001		Rooted	Subtracted	65.4147	68.8149	3.4002
	1044			Divided			1.05198
	1606		Ranked		207.916	204.662	1.0159
	1609			Subtracted			3.254
apolipoprotein b-100 precursor (apo b-100) [contains: apolipoprotein b-48 (apo b-48)]. [swissprot;acc:p04114]	1294	APOB	Squared		26174.3	29098.4	2924.1
	1563			Divided			1.11172
	1644		Measured		5782.92	6186.39	1.06977
	1681			Subtracted			403.47
	2104		Rooted	Divided	61.9958	63.5389	1.02489
	2113			Subtracted			1.5431
	2128		Ranked		217.871	219.366	1.495
	2151			Divided			1.00686
apopain precursor (ec 3.4.22.-) (cysteine protease cpp32) (yama protein) (cpp-32) (caspase-3) (casp-3) (srebp cleavage activity 1) (sca-1). [swissprot;acc:p42574]	949	CASP3	Measured		4633.48	5084.24	1.09728
	1026		Rooted		55.3631	58.2965	1.05298
	1160			Subtracted			2.9334
	1166		Ranked		233.942	228.46	5.482
	1293			Divided			1.024
	1338		Squared		18648.8	21012.8	1.12676
	1416		Measured	Subtracted	4633.48	5084.24	450.76
	1706		Squared		18648.8	21012.8	2364
apoptosis antagonizing transcription factor. [refseq;acc:nm_012138]	853	AATF	Measured	Divided	4078.45	4502.32	1.10393
	861		Rooted		51.8245	55.0559	1.06235
	929		Ranked	Subtracted	243.045	235.422	7.623
	1014			Divided			1.03238
	1049		Rooted	Subtracted	51.8245	55.0559	3.2314

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.