MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2225 to 2274 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Interaction Map	red	green	network_comparison
dynein 2 light intermediate chain. [refseq;acc:nm_016008]	4645	DYNC2LI1	Low confidence	205.746	204.424	1.00647
dynein heavy chain, cytosolic (dyhc) (cytoplasmic dynein heavy chain 1) (dhc1) (fragment). [swissprot;acc:q14204]	3040	no value		200.28	197.007	1.01661
dynein intermediate chain 1, axonemal (axonemal dynein intermediate chain 1). [swissprot;acc:q9ui46]	2379	DNAI1		201.741	198.068	1.01854
	3029		High confidence	0.00001	0.00001	1
dynein intermediate chain 1, cytosolic (dh ic-1) (cytoplasmic dynein intermediate chain 1). [swissprot;acc:o14576]	332	DYNC1I1	Low confidence	209.495	201.474	1.03981
	1005		High confidence	225.448	218.232	1.03307
dynein intermediate chain 2, cytosolic (dh ic-2) (cytoplasmic dynein intermediate chain 2). [swissprot;acc:q13409]	346	DYNC1I2	Low confidence	209.221	201.38	1.03894
	998		High confidence	225.557	218.271	1.03338
dynein light chain 1, cytoplasmic (8 kda dynein light chain) (dlc8) (protein inhibitor of neuronal nitric oxide synthase) (pin). [swissprot;acc:q15701]	2469	DYNLL1	Low confidence	200.964	197.356	1.01828
dynein light chain 2. [refseq;acc:nm_080677]	647	DYNLL2	High confidence	216.731	229.549	1.05914
	3775		Low confidence	203.61	200.926	1.01336
dynein light chain-a. [refseq;acc:nm_016141]	4650	DYNC1LI1		201.044	199.779	1.00633
dynein light intermediate chain 2, cytosolic (lic53/55) (lic-2). [swissprot;acc:o43237]	4651	DYNC1LI2
dyskerin (nucleolar protein nap57) (cbf5 homolog). [swissprot;acc:o60832]	1085	DKC1	High confidence	231.007	237.864	1.02968
	3195		Low confidence	201.952	198.76	1.01606
dystrobrevin alpha (dystrobrevin-alpha). [swissprot;acc:q9y4j8]	2583	DTNA	High confidence	213.415	213.743	1.00154
	3273		Low confidence	202.385	199.257	1.0157
dystrobrevin beta (beta-dystrobrevin) (dtn-b). [swissprot;acc:o60941]	2581	DTNB	High confidence	213.428	213.756	1.00154
	3289		Low confidence	202.385	199.26	1.01568
dystrobrevin binding protein 1; dysbindin. [refseq;acc:nm_032122]	951	DTNBP1		203.779	198.841	1.02483
	1599		High confidence	217.871	214.404	1.01617
dystrophin. [swissprot;acc:p11532]	2584	no value		213.422	213.75	1.00154
	2983		Low confidence	202.535	199.191	1.01679
e-1 enzyme. [refseq;acc:nm_021204]	1836	ENOPH1		199.38	195.479	1.01996
	2251		High confidence	208.315	207.061	1.00606
e1a binding protein p400; p400 swi2/snf2-related protein; cagh32 protein; trinucleotide repeat containing 12. [refseq;acc:nm_015409]	1984	EP400		219.26	217.193	1.00952
	3366		Low confidence	201.397	198.331	1.01546
e1b-55kda-associated protein 5 isoform a. [refseq;acc:nm_007040]	484	HNRPUL1	High confidence	237.109	254.667	1.07405
	1073		Low confidence	210.723	205.809	1.02388
e2a-pbx1-associated protein; putative 47 kda protein. [refseq;acc:nm_020140]	442	ANKS1B	High confidence	223.802	207.55	1.0783
	1851		Low confidence	203.171	199.205	1.01991
eap30 subunit of ell complex. [refseq;acc:nm_007241]	163	SNF8	High confidence	209.299	249.187	1.19058
	4022		Low confidence	201.796	199.494	1.01154
early endosome antigen 1, 162kd; early endosome-associated protein. [refseq;acc:nm_003566]	1660	EEA1	High confidence	228.654	231.933	1.01434
	2795		Low confidence	201.281	197.852	1.01733
early growth response protein 1 (egr-1) (krox-24 protein) (zif268) (nerve growth factor-induced protein a) (ngfi-a) (transcription factor etr103) (zinc finger protein 225) (at225). [swissprot;acc:p18146]	3530	EGR1		200.601	197.684	1.01476
early growth response protein 2 (egr-2) (krox-20 protein) (at591). [swissprot;acc:p11161]	3535	EGR2		200.624	197.712	1.01473
early growth response protein 3 (egr-3) (zinc finger protein pilot). [swissprot;acc:q06889]	3533	EGR3		200.623	197.711
early growth response protein 4 (egr-4) (at133). [swissprot;acc:q05215]	3538	EGR4		200.628	197.717	1.01472
early hematopoietic zinc finger. [refseq;acc:nm_015461]	825	no value		204.914	199.706	1.02608
ebna-2 co-activator (100kd). [refseq;acc:nm_014390]	2177			201.91	198.138	1.01904
ebp50-pdz interactor of 64 kda (epi64 protein). [swissprot;acc:q9bxi6]	203	TBC1D10A	High confidence	201.515	228.752	1.13516
	1051		Low confidence	200.439	205.267	1.02409
ecotropic viral integration site 5; neuroblastoma stage 4s gene. [refseq;acc:nm_005665]	1437	EVI5	High confidence	218.829	214.493	1.02022
	2480		Low confidence	200.094	196.506	1.01826
ecotropic virus integration 1 site protein. [swissprot;acc:q03112]	1214	EVI1		203.266	198.72	1.02288
	3170		High confidence	0.00001	0.00001	1
ectonucleoside triphosphate diphosphohydrolase 6 (ec 3.6.1.6) (ntpdase6) (cd39 antigen-like 2). [swissprot;acc:o75354]	1269	no value	Low confidence	196.818	192.485	1.02251
eferin. [swissprot;acc:o75154]	154	RAB11FIP3		183.27	172.702	1.06119
egf-like-domain, multiple 7; neu1 protein. [refseq;acc:nm_016215]	200	EGFL7	High confidence	242.718	276.018	1.1372

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.