MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Network Comparison Type	Rank	Gene	description	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 223 to 272 of 2061 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Hugo	Value Type
2811	vascular endothelial growth factor b precursor (vegf-b) (vegf related factor) (vrf). [swissprot;acc:p49765]	VEGFB	Squared
			Rooted
2812	mob-lak. [refseq;acc:nm_130807]	MOBKL2A	Measured
			Ranked
			Squared
			Rooted
2813	histone deacetylase 3 (hd3) (rpd3-2). [swissprot;acc:o15379]	HDAC3	Measured
			Ranked
			Squared
			Rooted
2814	spry domain-containing socs box protein ssb-1. [refseq;acc:nm_025106]	SPSB1	Measured
			Ranked
			Squared
			Rooted
2815	g protein-coupled receptor 66. [refseq;acc:nm_006056]	NMUR1	Measured
			Ranked
			Squared
			Rooted
2816	tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702]	TIGD1	Measured
			Ranked
			Squared
			Rooted
2817	tubulin-specific chaperone a (tubulin-folding cofactor a) (cfa) (tcp1-chaperonin cofactor a). [swissprot;acc:o75347]	TBCA	Measured
			Ranked
			Squared
			Rooted
2818	udp-glucuronosyltransferase 2b7 precursor, microsomal (ec 2.4.1.17) (udpgt) (3,4-catechol estrogen specific) (udpgth-2). [swissprot;acc:p16662]	UGT2B7	Measured
			Ranked
			Squared
			Rooted
2819	udp-glucuronosyltransferase 2b11 precursor, microsomal (ec 2.4.1.17) (udpgt). [swissprot;acc:o75310]	no value	Measured
			Ranked
			Squared
			Rooted
2820	peregrin (bromodomain and phd finger-containing protein 1) (br140 protein). [swissprot;acc:p55201]		Measured
			Ranked
			Squared
			Rooted
2821	vacuolar proton-atpase subunit. [sptrembl;acc:q8nhe4]	ATP6V0E2	Measured
			Ranked
			Squared
			Rooted
2822	zinc transporter 1 (znt-1). [swissprot;acc:q9y6m5]	SLC30A1	Measured
			Ranked
			Squared
			Rooted
2823	nuclear factor related to kappa b binding protein. [refseq;acc:nm_006165]	NFRKB	Measured
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.