MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 2180 to 2229 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	network_comparison	green
gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507]	658	GABRG2	Subtracted	214.256	12.116	202.14
gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928]	618	GABRG3	Divided		1.05994	202.139
	651		Subtracted		12.117
gamma-butyrobetaine,2-oxoglutarate dioxygenase (ec 1.14.11.1) (gamma-butyrobetaine hydroxylase) (gamma-bbh). [swissprot;acc:o75936]	1842	BBOX1	Divided	212.455	1.01115	210.113
	1854		Subtracted		2.342
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	3101	no value	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
gamma-sarcoglycan (gamma-sg) (35 kda dystrophin-associated glycoprotein) (35dag). [swissprot;acc:q13326]	1156	SGCG		218.186	5.514	212.672
	1181		Divided		1.02593
gamma-snap-associated factor 1; rab11-interacting protein. [refseq;acc:nm_015470]	1783	RAB11FIP5	Subtracted	220.462	2.536	217.926
	1817		Divided		1.01164
gamma-soluble nsf attachment protein (snap-gamma) (n-ethylmaleimide- sensitive factor attachment protein, gamma). [swissprot;acc:q99747]	110	NAPG	Subtracted	209.299	39.888	249.187
	166		Divided		1.19058
ganglioside-induced differentiation-associated protein 1-like 1. [refseq;acc:nm_024034]	1101	GDAP1L1	Subtracted	218.484	5.809	212.675
	1139		Divided		1.02731
ganglioside-induced differentiation-associated protein 1. [refseq;acc:nm_018972]	1103	GDAP1	Subtracted		5.809
	1141		Divided		1.02731
gastricsin precursor (ec 3.4.23.3) (pepsinogen c). [swissprot;acc:p20142]	2435	PGC	Subtracted	235.812	0.724	235.088
	2470		Divided		1.00308
gbp protein isoform a. [refseq;acc:nm_017870]	21	TMEM132A	Subtracted	325.586	69.094	256.492
	47		Divided		1.26938
gc-rich sequence dna-binding factor homolog. [swissprot;acc:q9y5b6]	2532	C21orf66	Subtracted	217.144	0.445	216.699
	2539		Divided		1.00205
gcn5-like protein 1 (rt14 protein). [swissprot;acc:p78537]	979	BLOC1S1		202.027	1.03399	195.386
	1023		Subtracted		6.641
gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488]	3125	POFUT1	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
gdp-mannose pyrophosphorylase a; mannose-1-phosphate guanylyltransferase (gdp). [refseq;acc:nm_013335]	1858	GMPPA		222.842	2.328	225.17
	1894		Divided		1.01045
gdp-mannose pyrophosphorylase b isoform 1; mannose-1-phosphate guanylyltransferase; amphoterin induced gene 3. [refseq;acc:nm_013334]	1857	GMPPB	Subtracted		2.328
	1893		Divided		1.01045
general control of amino acid synthesis protein 5-like 2 (ec 2.3.1.-) (histone acetyltransferase gcn5) (hsgcn5). [swissprot;acc:q92830]	2732	GCN5L2		202.233	1.00029	202.175
			Subtracted		0.058
general vesicular transport factor p115 (transcytosis associated protein) (tap) (vesicle docking protein). [swissprot;acc:o60763]	1890	USO1		220.659	2.207	218.452
	1923		Divided		1.0101
geranylgeranyl pyrophosphate synthetase (ggpp synthetase) (ggppsase) (geranylgeranyl diphosphate synthase) [includes: dimethylallyltransferase (ec 2.5.1.1); geranyltranstransferase (ec 2.5.1.10); farnesyltranstransferase (ec 2.5.1.29)]. [swissprot;acc:o95749]	2520	GGPS1	Subtracted	236.51	0.502	236.008
	2536		Divided		1.00213
geranylgeranyl transferase type i beta subunit (ec 2.5.1.-) (type i protein geranyl-geranyltransferase beta subunit) (ggtase-i-beta). [swissprot;acc:p53609]	1358	PGGT1B	Subtracted	225.039	4.534	229.573
	1438		Divided		1.02015
geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	2963	RABGGTB		0.00001	1	0.00001
			Subtracted	0	0	0
germ cell specific y-box binding protein; contrin. [refseq;acc:nm_015982]	2679	YBX2		208.438	0.197	208.635
	2685		Divided		1.00095
germ cell-less. [refseq;acc:nm_022471]	1780	no value		206.335	1.01206	203.877
	1804		Subtracted		2.458
gk001 protein. [refseq;acc:nm_020198]	2704	CCDC47	Divided	188.435	1.00066	188.311
	2712		Subtracted		0.124
glia maturation factor gamma (gmf-gamma). [swissprot;acc:o60234]	1323	GMFG		216.542	4.634	211.908
	1373		Divided		1.02187
glioma pathogenesis-related protein (glipr) (rtvp-1 protein). [swissprot;acc:p48060]	2953	GLIPR1		0.00001	1	0.00001

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.