MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Network Comparison Type	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

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Showing element 2101 to 2150 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	Interaction Map	red	green	network_comparison
bone morphogenetic protein 6 precursor (bmp-6). [swissprot;acc:p22004]	2843	Subtracted	BMP6	Low confidence	203.481	200.077	3.404
	2896	Divided		High confidence	0.00001	0.00001	1
		Subtracted			0	0	0
	2923	Divided		Low confidence	203.481	200.077	1.01701
bone morphogenetic protein 7 precursor (bmp-7) (osteogenic protein 1) (op-1). [swissprot;acc:p18075]	2864	Subtracted	BMP7		203.455	200.059	3.396
	2943	Divided					1.01697
	3128			High confidence	0.00001	0.00001	1
		Subtracted			0	0	0
bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820]	2773	Divided	BMP8A		0.00001	0.00001	1
		Subtracted			0	0	0
	2841			Low confidence	203.494	200.087	3.407
	2910	Divided					1.01703
brachyury protein (t protein). [swissprot;acc:o15178]	54	Subtracted	T		224.922	202.592	22.33
	56	Divided					1.11022
	2040			High confidence	210.586	208.803	1.00854
	2043	Subtracted					1.783
brain link protein-1 precursor. [swissprot;acc:q9gzv7]	2561		HAPLN2	Low confidence	203.73	200.174	3.556
	2642	Divided					1.01776
brain protein 16. [refseq;acc:nm_016458]	1835	Subtracted	no value	High confidence	216.811	219.195	2.384
	1847	Divided					1.011
	2180			Low confidence	188.304	184.788	1.01903
	2611	Subtracted					3.516
brain protein 44-like protein (hspc040) (cgi-129) (pnas-115). [swissprot;acc:q9y5u8]	1080	Divided	BRP44L		196.378	191.803	1.02385
	1154	Subtracted					4.575
brain protein 44. [swissprot;acc:o95563]	742	Divided	BRP44	High confidence	126.215	120.078	1.05111
	1040			Low confidence	182.902	178.58	1.0242
	1062	Subtracted		High confidence	126.215	120.078	6.137
	1381			Low confidence	182.902	178.58	4.322
branched-chain amino acid aminotransferase, cytosolic (ec 2.6.1.42) (bcat(c)) (eca39 protein). [swissprot;acc:p54687]	1867	Divided	BCAT1		199.922	196.027	1.01987
	1907	Subtracted					3.895
	2672	Divided		High confidence	210.957	210.741	1.00102
		Subtracted					0.216
branched-chain amino acid aminotransferase, mitochondrial precursor (ec 2.6.1.42) (bcat(m)) (placental protein 18) (pp18). [swissprot;acc:o15382]	1877	Divided	BCAT2	Low confidence	199.88	195.99	1.01985
	1914	Subtracted					3.89
	2681			High confidence	210.939	210.755	0.184
	2687	Divided					1.00087
brca1 associated protein. [refseq;acc:nm_006768]	3161		BRAP		0.00001	0.00001	1
		Subtracted			0	0	0
	4538	Divided		Low confidence	177.657	176.223	1.00814
	4604	Subtracted					1.434
brca1-associated ring domain protein 1 (bard-1). [swissprot;acc:q99728]	1745		BARD1	High confidence	216.271	218.991	2.72
	1752	Divided					1.01258
	3479			Low confidence	199.172	196.226	1.01501
	3509	Subtracted					2.946
brca2 and cdkn1a-interacting protein isoform bccipalpha; brca2 and cdkn1a-interacting protein; cdk inhibitor p21 binding protein; bccipalpha; bccipbeta; tok-1alpha; tok-1beta. [refseq;acc:nm_016567]	209		BCCIP	High confidence	240.782	265.717	24.935
	294	Divided					1.10356
	1466	Subtracted		Low confidence	202.583	198.329	4.254
	1490	Divided					1.02145
breast cancer antiestrogen resistance 3. [refseq;acc:nm_003567]	229		BCAR3	High confidence	226.401	202.094	1.12028
	232	Subtracted					24.307

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.