MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	description	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 208 to 257 of 473 in total

Value Type  : Ranked
Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
Filtered  : 1
green  : 0
network_comparison  : 0

description	Rank	Hugo
mitochondrial ribosomal protein s7; 30s ribosomal protein s7 homolog. [refseq;acc:nm_015971]	3016	MRPS7
mitochondrial solute carrier protein. [refseq;acc:nm_016612]	2915	SLC25A37
mitogen-activated protein kinase kinase 1 interacting protein 1 (mek binding partner 1) (mp1) (pro2783). [swissprot;acc:q9uha4]	3084	MAP2K1IP1
mo25 protein (cgi-66). [swissprot;acc:q9y376]	2976	CAB39
mo25-like protein. [swissprot;acc:q9h9s4]	3116	CAB39L
mob-lak. [refseq;acc:nm_130807]	2812	MOBKL2A
mondoa. [refseq;acc:nm_014938]	2800	MLXIP
mothers against decapentaplegic homolog interacting protein (madh-interacting protein) (smad anchor for receptor activation) (receptor activation anchor) (hsara) (novel serine protease) (nsp). [swissprot;acc:o95405]	2887	ZFYVE9
muts protein homolog 4. [swissprot;acc:o15457]	3194	MSH4
muts protein homolog 5. [swissprot;acc:o43196]	3148	no value
myeloblast kiaa0230 (fragment). [sptrembl;acc:q92626]	3000	PXDN
myosin heavy chain, nonmuscle type a (cellular myosin heavy chain, type a) (nonmuscle myosin heavy chain-a) (nmmhc-a). [swissprot;acc:p35579]	3140	MYH9
myosin heavy chain, nonmuscle type b (cellular myosin heavy chain, type b) (nonmuscle myosin heavy chain-b) (nmmhc-b). [swissprot;acc:p35580]	2988	MYH10
myosin heavy chain, smooth muscle isoform (smmhc). [swissprot;acc:p35749]	2985	MYH11
myotubularin-related protein 1 (ec 3.1.3.-). [swissprot;acc:q13613]	3190	MTMR1
myotubularin-related protein 2 (ec 3.1.3.-). [swissprot;acc:q13614]	3166	MTMR2
n-acetylglucosamine kinase (ec 2.7.1.59) (glcnac kinase). [swissprot;acc:q9uj70]	3022	NAGK
nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]	3005	NDUFA5
nadh-ubiquinone oxidoreductase 24 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3). [swissprot;acc:p19404]	2795	NDUFV2
nadh-ubiquinone oxidoreductase 30 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-30kd) (ci-30kd). [swissprot;acc:o75489]	3081	PTPMT1
nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	2954	NDUFA9
nadh-ubiquinone oxidoreductase 49 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-49kd) (ci-49kd). [swissprot;acc:o75306]	2878	NDUFS2
nanos (fragment). [sptrembl;acc:q8wy41]	2803	no value
neuromedin u receptor 2. [refseq;acc:nm_020167]	2991	NMUR2
ngd5 protein homolog (cgi-53). [swissprot;acc:q9y366]	3133	IFT52
nipsnap1 protein. [swissprot;acc:q9bpw8]	2770	NIPSNAP1
nipsnap2 protein (glioblastoma amplified sequence). [swissprot;acc:o75323]	2918	GBAS
nk6 transcription factor related, locus 2; nk homeobox family 6, b; glial and testis-specific homeobox protein; homeobox 6b. [refseq;acc:nm_177400]	2909	NKX6-2
nov protein homolog precursor (novh) (nephroblastoma overexpressed gene protein homolog). [swissprot;acc:p48745]	2970	NOV
nuclear autoantigen sp-100 (speckled 100 kda) (nuclear dot-associated sp100 protein) (lysp100b). [swissprot;acc:p23497]	3184	SP100
nuclear factor related to kappa b binding protein. [refseq;acc:nm_006165]	2823	NFRKB
nuclear pore complex protein nup214 (nucleoporin nup214) (214 kda nucleoporin) (can protein). [swissprot;acc:p35658]	3008	NUP214
nuclear transport factor 2 (ntf-2) (placental protein 15) (pp15). [swissprot;acc:p13662]	3113	NUTF2
nucleolar phosphoprotein p130 (nucleolar 130 kda protein) (140 kda nucleolar phosphoprotein) (nopp140) (nucleolar and coiled-body phosphoprotein 1). [swissprot;acc:q14978]	2842	NOLC1
nucleophosmin (npm) (nucleolar phosphoprotein b23) (numatrin) (nucleolar protein no38). [swissprot;acc:p06748]	2785	NPM1
nucleoplasmin 3. [swissprot;acc:o75607]	3096	NPM3
nucleoporin 50 kda (nuclear pore-associated protein 60 kda-like) (pro1146). [swissprot;acc:q9ukx7]	3154	NUP50
nucleosome assembly protein 1-like 1 (nap-1 related protein). [swissprot;acc:p55209]	2757	NAP1L1
nucleosome assembly protein 1-like 2 (brain-specific protein, x- linked). [swissprot;acc:q9ulw6]	2758	NAP1L2
nucleosome assembly protein 1-like 4 (nucleosome assembly protein 2) (nap2). [swissprot;acc:q99733]	3080	no value
origin recognition complex subunit 2. [swissprot;acc:q13416]	3047	ORC2L
origin recognition complex subunit 5. [swissprot;acc:o43913]	2851	ORC5L
orphan nuclear receptor nr5a2 (alpha-1-fetoprotein transcription factor) (hepatocytic transcription factor) (b1-binding factor) (hb1f) (cyp7a promoter binding factor). [swissprot;acc:o00482]	3042	NR5A2
pak1 interacting protein 1; pak1-interacting protein; pak/plc-interacting protein 1. [refseq;acc:nm_017906]	3072	PAK1IP1
pantothenate kinase 4 (ec 2.7.1.33) (pantothenic acid kinase 4) (hpank4). [swissprot;acc:q9nve7]	2883	PANK4
peptide deformylase, mitochondrial precursor (ec 3.5.1.88) (pdf) (polypeptide deformylase). [swissprot;acc:q9hbh1]	2884	PDF
peregrin (bromodomain and phd finger-containing protein 1) (br140 protein). [swissprot;acc:p55201]	2820	no value
pericentrin 1; frount; nucleoporin nup75. [refseq;acc:nm_024844]	3015	NUP85
phosphate carrier protein, mitochondrial precursor (ptp). [swissprot;acc:q00325]	3176	SLC25A3
phosphatidylethanolamine-binding protein (pebp) (prostatic binding protein) (hcnppp) (neuropolypeptide h3) (raf kinase inhibitor protein) (rkip) [contains: hippocampal cholinergic neurostimulating peptide (hcnp)]. [swissprot;acc:p30086]	3162	PEBP1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.