MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	red	Network Comparison Type	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1962 to 2011 of 2060 in total

red  : 0
Network Comparison Type  : Subtracted
network_comparison  : 0
Interaction Map  : High confidence
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type
udp-glucuronosyltransferase 2b7 precursor, microsomal (ec 2.4.1.17) (udpgt) (3,4-catechol estrogen specific) (udpgth-2). [swissprot;acc:p16662]	2818	UGT2B7	Ranked
			Squared
			Rooted
uncharacterized bone marrow protein bm033. [refseq;acc:nm_018452]	3030	C6orf35	Measured
			Ranked
			Squared
			Rooted
uridine diphosphate glucose pyrophosphatase. [refseq;acc:nm_177533]	2772	NUDT14	Measured
			Ranked
			Squared
			Rooted
uroporphyrinogen decarboxylase (ec 4.1.1.37) (uro-d) (upd). [swissprot;acc:p06132]	3010	UROD	Measured
			Ranked
			Squared
			Rooted
vaccinia related kinase 1; vaccinia-related kinase-1. [refseq;acc:nm_003384]	3136	VRK1	Measured
			Ranked
			Squared
			Rooted
vaccinia related kinase 2; vaccinia-related kinase-2. [refseq;acc:nm_006296]	3204	VRK2	Measured
			Ranked
			Squared
			Rooted
vacuolar atp synthase membrane sector associated protein m8-9 (v-atpase m8.9 subunit). [swissprot;acc:o75787]	2782	ATP6AP2	Measured
			Ranked
			Squared
			Rooted
vacuolar atp synthase subunit h (ec 3.6.3.14) (v-atpase h subunit) (vacuolar proton pump h subunit) (v-atpase m9.2 subunit) (v-atpase 9.2 kda membrane accessory protein). [swissprot;acc:o15342]	3055	ATP6V0E1	Measured
			Ranked
			Squared
			Rooted
vacuolar protein sorting factor 4a; skd1-homolog; vacuolar sorting protein 4. [refseq;acc:nm_013245]	2993	VPS4A	Measured
			Ranked
			Squared
			Rooted
vacuolar proton-atpase subunit. [sptrembl;acc:q8nhe4]	2821	ATP6V0E2	Measured
			Ranked
			Squared
			Rooted
vascular endothelial growth factor a precursor (vegf-a) (vascular permeability factor) (vpf). [swissprot;acc:p15692]	3066	VEGFA	Measured
			Ranked
			Squared
			Rooted
vascular endothelial growth factor b precursor (vegf-b) (vegf related factor) (vrf). [swissprot;acc:p49765]	2811	VEGFB	Measured
			Ranked
			Squared
			Rooted
vasopressin-activated calcium-mobilizing receptor (vacm-1) (cullin homolog 5) (cul-5). [swissprot;acc:q93034]	2840	CUL5	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.