MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 194 to 243 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998]	1481	PSMC2	Squared	Divided	26142.6	29163.8	1.11557
	1539		Measured		5783.97	6207.5	1.07322
	1622			Subtracted			423.53
	1979		Rooted	Divided	61.9542	63.6738	1.02776
	2006			Subtracted			1.7196
	2394		Ranked		218.192	219.014	0.822
	2395			Divided			1.00377
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	453	PSMC5	Squared	Subtracted	59318.4	53788.1	5530.3
	1637		Ranked	Divided	202.358	199.408	1.01479
	1682			Subtracted			2.95
	1721		Squared	Divided	59318.4	53788.1	1.10282
	1772		Rooted	Subtracted	74.9362	76.9113	1.9751
	2059			Divided			1.02636
	2602		Measured	Subtracted	9150.44	9234.09	83.65
	2651			Divided			1.00914
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	1280	PSMC6	Squared	Subtracted	27176.8	30113.9	2937.1
	1577		Measured	Divided	5923.66	6349.04	1.07181
	1599			Subtracted			425.38
	1630		Squared	Divided	27176.8	30113.9	1.10807
	1944		Rooted		62.7515	64.5421	1.02853
	1968			Subtracted			1.7906
	2478		Ranked	Divided	216.177	216.801	1.00289
	2486			Subtracted			0.624
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	1182	PSMD1	Squared		26860.7	29969	3108.3
	1476			Divided			1.11572
	1862		Measured	Subtracted	5826	6195.48	369.48
	1883			Divided			1.06342
	2129		Rooted		62.0038	63.5033	1.02418
	2140			Subtracted			1.4995
	2355		Ranked		218.555	219.434	0.879
	2368			Divided			1.00402
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	1249	PSMD10	Squared	Subtracted	26432.8	29419.4	2986.6
	1537			Divided			1.11299
	1609		Measured		5826.74	6242.44	1.07134
	1646			Subtracted			415.7
	2061		Rooted		62.2279	63.8594	1.6315
	2064			Divided			1.02622
	2256		Ranked	Subtracted	217.419	218.627	1.208
	2269			Divided			1.00556
26s proteasome non-atpase regulatory subunit 11 (26s proteasome regulatory subunit s9) (26s proteasome regulatory subunit p44.5). [swissprot;acc:o00231]	1278	PSMD11	Squared	Subtracted	26736.9	29677.3	2940.4
	1586			Divided			1.10998
	1592		Measured		5853.1	6271.79	1.07153
	1634			Subtracted			418.69
	2016		Rooted		62.2803	63.9816	1.7013
	2026			Divided			1.02732
	2353		Ranked	Subtracted	217.589	218.475	0.886
	2367			Divided			1.00407
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	1248	no value	Squared	Subtracted	26551.2	29539	2987.8
	1541			Divided			1.11253
	1579		Measured		5842.44	6261.87	1.07179

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.