MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1930 to 1979 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	network_comparison	green
barrier-to-autointegration factor (breakpoint cluster region protein 1). [swissprot;acc:o75531]	3579	BANF1	Divided	Low confidence	202.517	1.01447	199.628
basic helix-loop-helix domain containing, class b, 5; trinucleotide repeat containing 20. [refseq;acc:nm_152414]	933	BHLHB5		High confidence	159.165	1.03635	164.951
	1111		Subtracted			5.786
	4972		Divided	Low confidence	197.202	1.00084	197.037
	4973		Subtracted			0.165
basic leucine zipper nuclear factor 1 (jem-1); basic-leucine zipper nuclear factor; likely ortholog of mouse golgin-45. [refseq;acc:nm_003666]	4086	BLZF1	Divided		201.76	1.01096	199.573
			Subtracted			2.187
basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811]	1702	no value			201.552	4.035	197.517
	1732		Divided			1.02043
	2715			High confidence	216.018	1.00053	215.903
			Subtracted			0.115
bax inhibitor-1 (bi-1) (testis enhanced gene transcript). [swissprot;acc:p55061]	2950	TEGT	Divided		0.00001	1	0.00001
			Subtracted		0	0	0
	3005		Divided	Low confidence	140.432	1.01672	138.122
	4012		Subtracted			2.31
bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]	2776	BCOR	Divided	High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
	4959		Divided	Low confidence	202.187	1.00107	201.971
	4961		Subtracted			0.216
bcl2-related ovarian killer. [refseq;acc:nm_032515]	17	BOK			265.638	42.403	223.235
	30		Divided			1.18995
bcl2/adenovirus e1b 19-kda protein-interacting protein 1. [swissprot;acc:q12981]	4492	BNIP1	Subtracted		202.09	1.763	203.853
	4497		Divided			1.00872
beclin 1 (coiled-coil myosin-like bcl2-interacting protein) (protein gt197). [swissprot;acc:q14457]	1636	BECN1		High confidence	202.358	1.01479	199.408
	1681		Subtracted			2.95
	2036		Divided	Low confidence	199.664	1.01938	195.869
	2082		Subtracted			3.795
bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	11	BEST1	Divided		37.318	1.30966	28.4944
	273		Subtracted			8.8236
bet3 homolog. [swissprot;acc:o43617]	327	TRAPPC3	Divided		197.221	1.04034	189.574
	348		Subtracted			7.647
	567		Divided	High confidence	129.219	1.06563	121.261
	910		Subtracted			7.958
bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8]	1058	TRAPPC1	Divided	Low confidence	198.804	1.02401	194.142
	1093		Subtracted			4.662
beta adducin (erythrocyte adducin beta subunit). [swissprot;acc:p35612]	1448	ADD2			205.847	4.27	201.577
	1549		Divided			1.02118
	1897		Subtracted	High confidence	224.343	2.192	222.151
	1945		Divided			1.00987
beta enolase (ec 4.2.1.11) (2-phospho-d-glycerate hydro-lyase) (skeletal muscle enolase) (mse) (enolase 3). [swissprot;acc:p13929]	2361	ENO3			207.186	1.00415	208.046
	2364		Subtracted			0.86
	4628		Divided	Low confidence	201.961	1.00667	200.622
	4633		Subtracted			1.339
beta tubulin 1, class vi. [refseq;acc:nm_030773]	2985	TUBB1	Divided		200.1	1.01678	196.798
	3000		Subtracted			3.302
beta-1,3-galactosyltransferase 5 (ec 2.4.1.-) (beta-1,3-galtase 5) (beta3gal-t5) (b3gal-t5) (udp-galactose:beta-n-acetylglucosamine beta- 1,3-galactosyltransferase 5) (udp-gal:beta-glcnac beta-1,3- galactosyltransferase 5) (beta-3-gx-t5). [swissprot;acc:q9y2c3]	3631	B3GALT5	Divided		200.633	1.01418	197.828
	3639		Subtracted			2.805
beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	301	ALG1	Divided	High confidence	150.982	1.10193	166.372
	492		Subtracted			15.39
	4906		Divided	Low confidence	179.202	1.00195	179.551

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.