MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Network Comparison Type	Hugo	Value Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1908 to 1957 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	Interaction Map	red	network_comparison	green
bai1-associated protein 3; bai-associated protein 3. [refseq;acc:nm_003933]	890	Divided	BAIAP3	Low confidence	202.277	1.02546	197.255
band 3 anion transport protein (anion exchange protein 1) (ae 1) (cd233 antigen). [swissprot;acc:p02730]	3861	Subtracted	SLC4A1		204.576	2.576	202
	3885	Divided				1.01275
band 4.1-like protein 1 (neuronal protein 4.1) (4.1n). [swissprot;acc:q9h4g0]	2144		EPB41L1	High confidence	206.443	1.00688	207.864
	2163	Subtracted				1.421
	2665	Divided		Low confidence	199.624	1.01768	196.156
	2688	Subtracted				3.468
band 4.1-like protein 2 (generally expressed protein 4.1) (4.1g). [swissprot;acc:o43491]	2146	Divided	EPB41L2	High confidence	206.443	1.00688	207.864
	2164	Subtracted				1.421
	2666	Divided		Low confidence	199.624	1.01768	196.156
	2689	Subtracted				3.468
band 4.1-like protein 3 (4.1b) (differentially expressed in adenocarcinoma of the lung protein 1) (dal-1). [swissprot;acc:q9y2j2]	2145	Divided	EPB41L3	High confidence	206.442	1.00688	207.862
	2166	Subtracted				1.42
	2661	Divided		Low confidence	199.622	1.01769	196.153
	2685	Subtracted				3.469
bardet-biedl syndrome 7 protein isoform a; bbs2-like 1. [refseq;acc:nm_176824]	607		BBS7		207.763	5.881	201.882
	635	Divided				1.02913
	1550	Subtracted		High confidence	221.128	3.639	224.767
	1567	Divided				1.01646
barrier-to-autointegration factor (breakpoint cluster region protein 1). [swissprot;acc:o75531]	2804		BANF1		0.00001	1	0.00001
		Subtracted			0	0	0
	3566			Low confidence	202.517	2.889	199.628
	3579	Divided				1.01447
basic helix-loop-helix domain containing, class b, 5; trinucleotide repeat containing 20. [refseq;acc:nm_152414]	933		BHLHB5	High confidence	159.165	1.03635	164.951
	1111	Subtracted				5.786
	4972	Divided		Low confidence	197.202	1.00084	197.037
	4973	Subtracted				0.165
basic leucine zipper nuclear factor 1 (jem-1); basic-leucine zipper nuclear factor; likely ortholog of mouse golgin-45. [refseq;acc:nm_003666]	4086	Divided	BLZF1		201.76	1.01096	199.573
		Subtracted				2.187
basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811]	1702		no value		201.552	4.035	197.517
	1732	Divided				1.02043
	2715			High confidence	216.018	1.00053	215.903
		Subtracted				0.115
bax inhibitor-1 (bi-1) (testis enhanced gene transcript). [swissprot;acc:p55061]	2950	Divided	TEGT		0.00001	1	0.00001
		Subtracted			0	0	0
	3005	Divided		Low confidence	140.432	1.01672	138.122
	4012	Subtracted				2.31
bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]	2776	Divided	BCOR	High confidence	0.00001	1	0.00001
		Subtracted			0	0	0
	4959	Divided		Low confidence	202.187	1.00107	201.971
	4961	Subtracted				0.216
bcl2-related ovarian killer. [refseq;acc:nm_032515]	17		BOK		265.638	42.403	223.235
	30	Divided				1.18995
bcl2/adenovirus e1b 19-kda protein-interacting protein 1. [swissprot;acc:q12981]	4492	Subtracted	BNIP1		202.09	1.763	203.853
	4497	Divided				1.00872
beclin 1 (coiled-coil myosin-like bcl2-interacting protein) (protein gt197). [swissprot;acc:q14457]	1636		BECN1	High confidence	202.358	1.01479	199.408
	1681	Subtracted				2.95
	2036	Divided		Low confidence	199.664	1.01938	195.869
	2082	Subtracted				3.795
bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	11	Divided	BEST1		37.318	1.30966	28.4944

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.