MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1901 to 1950 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	network_comparison	green
epsin 3. [refseq;acc:nm_017957]	2280	EPN3	Subtracted	218.153	1.131	219.284
	2297		Divided		1.00518
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	3177	LMAN1		0.00001	1	0.00001
			Subtracted	0	0	0
ero1-like. [refseq;acc:nm_014584]	905	no value		217.168	7.961	209.207
	911		Divided		1.03805
erythroid differentiation and denucleation factor 1. [swissprot;acc:o60584]	1549	SLMO1	Subtracted	221.128	3.639	224.767
	1566		Divided		1.01646
erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	3095	C10orf137		0.00001	1	0.00001
			Subtracted	0	0	0
espin. [refseq;acc:nm_031475]	1195	ESPNP		219.354	5.346	224.7
	1257		Divided		1.02437
esterase d (ec 3.1.1.1). [swissprot;acc:p10768]	2429	ESD		192.871	1.00355	193.555
	2446		Subtracted		0.684
estradiol 17 beta-dehydrogenase 1 (ec 1.1.1.62) (17-beta-hsd 1) (placental 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-hsd) (e2dh). [swissprot;acc:p14061]	1028	HSD17B1		211.449	6.549	217.998
	1050		Divided		1.03097
estradiol 17 beta-dehydrogenase 4 (ec 1.1.1.62) (17-beta-hsd 4) (17-beta-hydroxysteroid dehydrogenase 4). [swissprot;acc:p51659]	1768	HSD17B4		185.276	1.01219	187.534
	1876		Subtracted		2.258
estrogen-related receptor gamma (estrogen receptor related protein 3) (err gamma-2). [swissprot;acc:o75454]	1042	no value	Divided	186.799	1.03132	181.127
	1123		Subtracted		5.672
ethanolamine kinase (ec 2.7.1.82) (eki). [swissprot;acc:q9hbu6]	2375	ETNK1		212.724	0.85	213.574
	2378		Divided		1.004
ethanolamine kinase-like protein eki2 (flj10761). [swissprot;acc:q9nvf9]	2374	ETNK2	Subtracted		0.85
	2377		Divided		1.004
ethanolamine-phosphate cytidylyltransferase (ec 2.7.7.14) (phosphorylethanolamine transferase) (ctp:phosphoethanolamine cytidylyltransferase). [swissprot;acc:q99447]	1702	PCYT2	Subtracted	233.45	2.855	230.595
	1758		Divided		1.01238
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]	2868	SNORA67		0.00001	1	0.00001
			Subtracted	0	0	0
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]	2888	EIF4A2	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
eukaryotic peptide chain release factor subunit 1 (erf1) (eukaryotic release factor 1) (tb3-1) (c11 protein). [swissprot;acc:p46055]	753	ETF1		210.946	10.279	221.225
	772		Divided		1.04873
eukaryotic translation initiation factor 2 subunit 1 (eukaryotic translation initiation factor 2 alpha subunit) (eif-2-alpha) (eif- 2alpha) (eif-2a). [swissprot;acc:p05198]	1269	EIF2S1	Subtracted	226.433	5.058	231.491
	1341		Divided		1.02234
eukaryotic translation initiation factor 2 subunit 2 (eukaryotic translation initiation factor 2 beta subunit) (eif-2-beta). [swissprot;acc:p20042]	1798	EIF2S2	Subtracted	221.525	2.476	224.001
	1839		Divided		1.01118
eukaryotic translation initiation factor 2 subunit 3 (eukaryotic translation initiation factor 2 gamma subunit) (eif-2-gamma). [swissprot;acc:p41091]	1832	EIF2S3	Subtracted	221.639	2.407	224.046
	1865		Divided		1.01086
eukaryotic translation initiation factor 3 subunit 10 (eif-3 theta) (eif3 p167) (eif3 p180) (eif3 p185) (eif3a). [swissprot;acc:q14152]	816	EIF3A	Subtracted	246.354	9.131	237.223
	904		Divided		1.03849
eukaryotic translation initiation factor 3 subunit 11 (eif-3 p25) (eif3k) (muscle specific gene m9 protein) (ptd001) (hspc029) (arg134). [swissprot;acc:q9ubq5]	1548	EIF3K	Subtracted	221.128	3.639	224.767
	1565		Divided		1.01646
eukaryotic translation initiation factor 3 subunit 2 (eif-3 beta) (eif3 p36) (eif3i) (tgf-beta receptor interacting protein 1) (trip-1). [swissprot;acc:q13347]	666	EIF3I	Subtracted	250.465	12.085	238.38
	746		Divided		1.0507
eukaryotic translation initiation factor 3 subunit 4 (eif-3 delta) (eif3 p44) (eif-3 rna-binding subunit) (eif3 p42) (eif3g). [swissprot;acc:o75821]	815	EIF3G	Subtracted	246.354	9.131	237.223
	903		Divided		1.03849
eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [swissprot;acc:q9y262]	1554	EIF3EIP	Subtracted	221.128	3.639	224.767
	1571		Divided		1.01646
eukaryotic translation initiation factor 3 subunit 7 (eif-3 zeta) (eif3 p66) (eif3d). [swissprot;acc:o15371]	1904	EIF3D	Subtracted	219.753	2.179	217.574
	1931		Divided		1.01001

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.